SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2dax'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNX_A_T44A501_1
(THYROID HORMONE
RECEPTOR ALPHA)		 2dax PROTEIN C21ORF6
(Homo
sapiens) 		4 / 6 SER A  96
GLN A 104
VAL A 132
THR A 129
 None
 1.37A 4lnxA-2daxA:
undetectable		 4lnxA-2daxA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)		 2dax PROTEIN C21ORF6
(Homo
sapiens) 		3 / 3 HIS A 135
GLU A 134
TRP A 131
 None
 0.79A 5odiD-2daxA:
undetectable		 5odiD-2daxA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODQ_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)		 2dax PROTEIN C21ORF6
(Homo
sapiens) 		3 / 3 HIS A 135
GLU A 134
TRP A 131
 None
 0.87A 5odqD-2daxA:
undetectable		 5odqD-2daxA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODR_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)		 2dax PROTEIN C21ORF6
(Homo
sapiens) 		3 / 3 HIS A 135
GLU A 134
TRP A 131
 None
 0.77A 5odrD-2daxA:
undetectable		 5odrD-2daxA:
18.67