SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2day'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ICU_A_NIOA221_1 (OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE)	2day	RING FINGER PROTEIN 25 (Homo sapiens)	4 / 6	SER A 123 PHE A 61 GLU A 120 GLY A 118	None	1.14A	1icuA-2dayA: undetectable 1icuB-2dayA: undetectable	1icuA-2dayA: 22.17 1icuB-2dayA: 22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KQB_A_BEZA524_0 (OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE)	2day	RING FINGER PROTEIN 25 (Homo sapiens)	4 / 6	SER A 123 PHE A 61 GLU A 120 GLY A 118	None	1.15A	1kqbA-2dayA: undetectable 1kqbB-2dayA: undetectable	1kqbA-2dayA: 21.63 1kqbB-2dayA: 21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3EM0_A_CHDA151_0 (ILEAL BILE ACID-BINDING PROTEIN)	2day	RING FINGER PROTEIN 25 (Homo sapiens)	5 / 10	ILE A 91 ILE A 94 LYS A 117 GLY A 118 VAL A 59	None	1.23A	3em0A-2dayA: undetectable	3em0A-2dayA: 23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NBQ_C_URFC400_1 (URIDINE PHOSPHORYLASE 1)	2day	RING FINGER PROTEIN 25 (Homo sapiens)	4 / 8	GLY A 118 LEU A 63 LEU A 46 ILE A 44	None	0.86A	3nbqC-2dayA: undetectable	3nbqC-2dayA: 17.18

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1ICU_A_NIOA221_1","OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE;OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE","2day","RING FINGER PROTEIN 25","Homo sapiens",4,"SER A 123;PHE A  61;GLU A 120;GLY A 118","None","1.14A","1icuA-2dayA:undetectable;1icuB-2dayA:undetectable","1icuA-2dayA:22.17;1icuB-2dayA:22.17"],["1KQB_A_BEZA524_0","OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE","2day","RING FINGER PROTEIN 25","Homo sapiens",4,"SER A 123;PHE A  61;GLU A 120;GLY A 118","None","1.15A","1kqbA-2dayA:undetectable;1kqbB-2dayA:undetectable","1kqbA-2dayA:21.63;1kqbB-2dayA:21.63"],["3EM0_A_CHDA151_0","ILEAL BILE ACID-BINDING PROTEIN","2day","RING FINGER PROTEIN 25","Homo sapiens",5,"ILE A  91;ILE A  94;LYS A 117;GLY A 118;VAL A  59","None","1.23A","3em0A-2dayA:undetectable","3em0A-2dayA:23.08"],["3NBQ_C_URFC400_1","URIDINE PHOSPHORYLASE 1","2day","RING FINGER PROTEIN 25","Homo sapiens",4,"GLY A 118;LEU A  63;LEU A  46;ILE A  44","None","0.86A","3nbqC-2dayA:undetectable","3nbqC-2dayA:17.18"]]