SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2daz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BDM_A_TMIA503_1
(CYTOCHROME P450 2B4)		 2daz INAD-LIKE PROTEIN
(Homo
sapiens) 		4 / 8 LEU A  76
VAL A 103
LEU A  31
VAL A  55
 None
 1.02A 2bdmA-2dazA:
undetectable		 2bdmA-2dazA:
14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMZ_B_ROCB401_3
(PROTEASE)		 2daz INAD-LIKE PROTEIN
(Homo
sapiens) 		6 / 12 GLY A  62
ALA A  64
ASP A  67
ILE A  29
ILE A  96
ILE A  58
 None
 1.46A 2nmzB-2dazA:
undetectable		 2nmzB-2dazA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_I_ACHI323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)		 2daz INAD-LIKE PROTEIN
(Homo
sapiens) 		4 / 8 ILE A  83
GLU A  78
TYR A  19
LEU A  22
 None
 1.04A 3rqwI-2dazA:
undetectable
3rqwJ-2dazA:
undetectable		 3rqwI-2dazA:
16.61
3rqwJ-2dazA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_C_ACTC502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 2daz INAD-LIKE PROTEIN
(Homo
sapiens) 		3 / 3 PRO A  63
ASP A  34
GLU A  32
 None
 0.89A 3v4tC-2dazA:
undetectable		 3v4tC-2dazA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_B_STRB601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 2daz INAD-LIKE PROTEIN
(Homo
sapiens) 		6 / 12 LEU A 105
ALA A  92
GLY A  39
ALA A  43
ILE A  53
VAL A  55
 None
 1.24A 4nkxB-2dazA:
undetectable		 4nkxB-2dazA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_B_STRB601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 2daz INAD-LIKE PROTEIN
(Homo
sapiens) 		6 / 12 LEU A 105
ALA A  92
ILE A  58
ALA A  43
ILE A  53
VAL A  55
 None
 1.15A 4nkxB-2dazA:
undetectable		 4nkxB-2dazA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_J_CHDJ103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 2daz INAD-LIKE PROTEIN
(Homo
sapiens) 		5 / 11 LEU A  38
LEU A  40
LEU A 105
GLU A  78
LEU A  76
 None
 1.17A 4wg0J-2dazA:
undetectable
4wg0K-2dazA:
undetectable
4wg0L-2dazA:
undetectable		 4wg0J-2dazA:
14.58
4wg0K-2dazA:
14.58
4wg0L-2dazA:
14.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGY_A_ERYA403_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 2daz INAD-LIKE PROTEIN
(Homo
sapiens) 		5 / 12 ILE A  58
GLY A  62
ASN A  59
GLU A  75
ILE A  79
 None
 1.19A 5igyA-2dazA:
undetectable		 5igyA-2dazA:
17.26