SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2db6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D8C_A_SORA4000_0
(MALATE SYNTHASE G)		 2db6 SH3 AND CYSTEINE
RICH DOMAIN 3
(Homo
sapiens) 		3 / 3 GLN A  66
HIS A  18
PRO A  17
 None
ZN  A 201 (-3.2A)
None
 0.80A 1d8cA-2db6A:
undetectable		 1d8cA-2db6A:
8.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWZ_B_BEZB301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 2db6 SH3 AND CYSTEINE
RICH DOMAIN 3
(Homo
sapiens) 		3 / 3 MET A  65
GLN A  66
ARG A  67
 None
 0.99A 5ewzB-2db6A:
undetectable		 5ewzB-2db6A:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9Y_A_ACTA409_0
(UNCHARACTERIZED
PROTEIN KDOO)		 2db6 SH3 AND CYSTEINE
RICH DOMAIN 3
(Homo
sapiens) 		3 / 3 LYS A  16
PRO A  17
LYS A  19
 None
 0.83A 5y9yA-2db6A:
undetectable		 5y9yA-2db6A:
10.56