SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2dba'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C12_F_SPMF1433_1
(NITROALKANE OXIDASE)		 2dba SMOOTH MUSCLE CELL
ASSOCIATED
PROTEIN-1, ISOFORM 2
(Homo
sapiens) 		5 / 11 LEU A 112
GLU A  85
ALA A  88
SER A 106
LEU A 109
 None
 1.31A 2c12F-2dbaA:
undetectable		 2c12F-2dbaA:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KMO_B_EAAB213_1
(GLUTATHIONE
S-TRANSFERASE P)		 2dba SMOOTH MUSCLE CELL
ASSOCIATED
PROTEIN-1, ISOFORM 2
(Homo
sapiens) 		4 / 7 TYR A 103
PHE A 135
VAL A 126
ASN A 141
 None
 1.14A 3kmoB-2dbaA:
undetectable		 3kmoB-2dbaA:
26.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3POC_B_ACRB665_1
(ALPHA-GLUCOSIDASE)		 2dba SMOOTH MUSCLE CELL
ASSOCIATED
PROTEIN-1, ISOFORM 2
(Homo
sapiens) 		4 / 6 ASP A  80
TYR A  81
ASP A  82
LYS A  83
 None
 1.03A 3pocB-2dbaA:
undetectable		 3pocB-2dbaA:
13.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_A_ACTA505_0
(RNA POLYMERASE
3D-POL)		 2dba SMOOTH MUSCLE CELL
ASSOCIATED
PROTEIN-1, ISOFORM 2
(Homo
sapiens) 		3 / 3 CYH A 125
ASN A 132
LYS A 100
 None
 1.11A 4k50A-2dbaA:
undetectable		 4k50A-2dbaA:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWV_A_BCZA513_1
(NEURAMINIDASE)		 2dba SMOOTH MUSCLE CELL
ASSOCIATED
PROTEIN-1, ISOFORM 2
(Homo
sapiens) 		3 / 3 ARG A 105
GLU A  93
ARG A 124
 None
 0.66A 4mwvA-2dbaA:
undetectable		 4mwvA-2dbaA:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_D_SORD1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 2dba SMOOTH MUSCLE CELL
ASSOCIATED
PROTEIN-1, ISOFORM 2
(Homo
sapiens) 		4 / 6 LYS A 100
GLY A  97
GLY A  96
ASP A  95
 None
 0.83A 5a06D-2dbaA:
undetectable		 5a06D-2dbaA:
21.43