SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2dbb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9V_B_DXCB323_0
(INVASIN IPAD)		 2dbb PUTATIVE HTH-TYPE
TRANSCRIPTIONAL
REGULATOR PH0061
(Pyrococcus
horikoshii) 		4 / 7 ILE A  53
VAL A  15
LEU A  18
SER A  19
 None
 0.69A 3r9vA-2dbbA:
undetectable
3r9vB-2dbbA:
undetectable		 3r9vA-2dbbA:
21.72
3r9vB-2dbbA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_C_STRC603_2
(CYTOCHROME P450
21-HYDROXYLASE)		 2dbb PUTATIVE HTH-TYPE
TRANSCRIPTIONAL
REGULATOR PH0061
(Pyrococcus
horikoshii) 		3 / 3 LEU A  29
VAL A  10
ASP A  11
 None
 0.56A 4y8wC-2dbbA:
undetectable		 4y8wC-2dbbA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_D_CHDD401_0
(BILE SALT HYDROLASE)		 2dbb PUTATIVE HTH-TYPE
TRANSCRIPTIONAL
REGULATOR PH0061
(Pyrococcus
horikoshii) 		5 / 10 ILE A 131
LEU A 128
PHE A 127
LEU A 141
LEU A 113
 None
 1.17A 5y7pD-2dbbA:
undetectable		 5y7pD-2dbbA:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_H_CHDH401_0
(BILE SALT HYDROLASE)		 2dbb PUTATIVE HTH-TYPE
TRANSCRIPTIONAL
REGULATOR PH0061
(Pyrococcus
horikoshii) 		5 / 10 ILE A 131
LEU A 128
PHE A 127
LEU A 141
LEU A 113
 None
 1.14A 5y7pH-2dbbA:
undetectable		 5y7pH-2dbbA:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F7L_B_ACTB503_0
(AMINE OXIDASE LKCE)		 2dbb PUTATIVE HTH-TYPE
TRANSCRIPTIONAL
REGULATOR PH0061
(Pyrococcus
horikoshii) 		3 / 3 VAL A 137
GLU A 138
ILE A  74
 None
 0.66A 6f7lB-2dbbA:
undetectable		 6f7lB-2dbbA:
15.16