SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2dbh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2J9D_J_ACTJ1116_0 (HYPOTHETICAL NITROGEN REGULATORY PII-LIKE PROTEIN MJ0059)	2dbh	TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 21 (Homo sapiens)	4 / 8	LYS A 76 ILE A 73 GLU A 52 ILE A 72	None	0.75A	2j9dJ-2dbhA: undetectable 2j9dK-2dbhA: 1.1 2j9dL-2dbhA: undetectable	2j9dJ-2dbhA: 20.00 2j9dK-2dbhA: 20.00 2j9dL-2dbhA: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Z4C_A_IPHA903_0 (PROTEIN ARGONAUTE-2)	2dbh	TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 21 (Homo sapiens)	4 / 6	ARG A 68 ILE A 72 ILE A 59 ASP A 64	None	1.17A	4z4cA-2dbhA: undetectable	4z4cA-2dbhA: 8.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Z4D_A_IPHA902_0 (PROTEIN ARGONAUTE-2)	2dbh	TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 21 (Homo sapiens)	4 / 6	ARG A 68 ILE A 72 ILE A 59 ASP A 64	None	1.19A	4z4dA-2dbhA: undetectable	4z4dA-2dbhA: 8.84