SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2dbn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT6_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 2dbn HYPOTHETICAL PROTEIN
YBIU
(Escherichia
coli) 		5 / 11 LEU A 289
VAL A 288
TYR A 217
LEU A 311
ARG A 240
 None
 1.28A 1kt6A-2dbnA:
undetectable		 1kt6A-2dbnA:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)		 2dbn HYPOTHETICAL PROTEIN
YBIU
(Escherichia
coli) 		5 / 12 ILE A  90
ALA A 416
SER A 181
SER A 152
TYR A  66
 None
 1.25A 1nbhA-2dbnA:
undetectable		 1nbhA-2dbnA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_C_SAMC2293_0
(GLYCINE
N-METHYLTRANSFERASE)		 2dbn HYPOTHETICAL PROTEIN
YBIU
(Escherichia
coli) 		5 / 12 ILE A  90
ALA A 416
SER A 181
SER A 152
TYR A  66
 None
 1.25A 1nbhC-2dbnA:
undetectable		 1nbhC-2dbnA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_D_SAMD3293_0
(GLYCINE
N-METHYLTRANSFERASE)		 2dbn HYPOTHETICAL PROTEIN
YBIU
(Escherichia
coli) 		5 / 12 ILE A  90
ALA A 416
SER A 181
SER A 152
TYR A  66
 None
 1.24A 1nbhD-2dbnA:
undetectable		 1nbhD-2dbnA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_B_CTXB1283_1
(CES1 PROTEIN)		 2dbn HYPOTHETICAL PROTEIN
YBIU
(Escherichia
coli) 		4 / 7 TRP A  61
LEU A  53
GLY A  57
PRO A 329
 None
 0.92A 1ya4B-2dbnA:
undetectable		 1ya4B-2dbnA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_A_DGXA1_2
(NUCLEAR RECEPTOR
ROR-GAMMA)		 2dbn HYPOTHETICAL PROTEIN
YBIU
(Escherichia
coli) 		3 / 3 TRP A 212
VAL A 279
ARG A  85
 None
 0.88A 3b0wA-2dbnA:
undetectable		 3b0wA-2dbnA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LB3_A_4CHA191_0
(DEHALOPEROXIDASE A)		 2dbn HYPOTHETICAL PROTEIN
YBIU
(Escherichia
coli) 		4 / 6 PHE A 257
HIS A 239
THR A 241
VAL A 243
 None
 1.00A 3lb3A-2dbnA:
undetectable		 3lb3A-2dbnA:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CCQ_A_ACTA1317_0
(THIOREDOXIN
REDUCTASE)		 2dbn HYPOTHETICAL PROTEIN
YBIU
(Escherichia
coli) 		3 / 3 LEU A  10
GLU A 210
SER A   7
 None
 0.78A 4ccqA-2dbnA:
undetectable		 4ccqA-2dbnA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2dbn HYPOTHETICAL PROTEIN
YBIU
(Escherichia
coli) 		4 / 7 ASP A 116
ASN A 113
GLU A 397
ASP A 111
 None
 1.11A 4fevB-2dbnA:
undetectable		 4fevB-2dbnA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2dbn HYPOTHETICAL PROTEIN
YBIU
(Escherichia
coli) 		4 / 7 ASP A 116
ASN A 113
GLU A 397
ASP A 111
 None
 1.12A 4fewB-2dbnA:
undetectable		 4fewB-2dbnA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2dbn HYPOTHETICAL PROTEIN
YBIU
(Escherichia
coli) 		4 / 8 ASP A 116
ASN A 113
GLU A 397
ASP A 111
 None
 1.12A 4gkhD-2dbnA:
undetectable		 4gkhD-2dbnA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2dbn HYPOTHETICAL PROTEIN
YBIU
(Escherichia
coli) 		4 / 7 LEU A 276
ARG A 258
PRO A 135
SER A 197
 None
 1.24A 4klrA-2dbnA:
undetectable		 4klrA-2dbnA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A7M_A_ACTA1923_0
(BETA-XYLOSIDASE)		 2dbn HYPOTHETICAL PROTEIN
YBIU
(Escherichia
coli) 		3 / 3 ASP A 186
ARG A 187
TYR A 361
 None
None
SO4  A 703 ( 4.2A)
 0.76A 5a7mA-2dbnA:
undetectable		 5a7mA-2dbnA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A7M_B_ACTB1924_0
(BETA-XYLOSIDASE)		 2dbn HYPOTHETICAL PROTEIN
YBIU
(Escherichia
coli) 		3 / 3 ASP A 186
ARG A 187
TYR A 361
 None
None
SO4  A 703 ( 4.2A)
 0.79A 5a7mB-2dbnA:
undetectable		 5a7mB-2dbnA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JNH_A_ASCA202_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 2dbn HYPOTHETICAL PROTEIN
YBIU
(Escherichia
coli) 		3 / 3 ASN A 371
PRO A 366
GLN A 159
 None
 0.94A 6jnhA-2dbnA:
undetectable		 6jnhA-2dbnA:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JOG_A_ASCA202_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 2dbn HYPOTHETICAL PROTEIN
YBIU
(Escherichia
coli) 		3 / 3 ASN A 371
PRO A 366
GLN A 159
 None
 0.94A 6jogA-2dbnA:
undetectable		 6jogA-2dbnA:
16.34