SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2dc5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_B_BEZB503_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 2dc5 GLUTATHIONE
S-TRANSFERASE, MU 7
(Mus
musculus) 		4 / 6 ARG A  25
ALA A  21
ILE A  83
PRO A  68
 None
 1.23A 1oniB-2dc5A:
undetectable
1oniC-2dc5A:
undetectable		 1oniB-2dc5A:
20.99
1oniC-2dc5A:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_C_SAMC301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 2dc5 GLUTATHIONE
S-TRANSFERASE, MU 7
(Mus
musculus) 		5 / 12 LEU A  28
LEU A  87
ARG A  39
ASP A  16
ALA A  21
 None
 1.11A 2br4C-2dc5A:
undetectable		 2br4C-2dc5A:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_A_RALA600_2
(ESTROGEN RECEPTOR)		 2dc5 GLUTATHIONE
S-TRANSFERASE, MU 7
(Mus
musculus) 		4 / 5 LEU A 107
ASP A 113
MET A 142
LEU A 188
 None
 1.30A 2jfaA-2dc5A:
undetectable		 2jfaA-2dc5A:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_B_SALB1305_1
(LYSR-TYPE REGULATORY
PROTEIN)		 2dc5 GLUTATHIONE
S-TRANSFERASE, MU 7
(Mus
musculus) 		4 / 5 SER A 146
ARG A 143
PRO A 139
GLY A 140
 None
 1.35A 2y7kB-2dc5A:
undetectable		 2y7kB-2dc5A:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHN_A_ACTA108_0
(PROTEIN P-30)		 2dc5 GLUTATHIONE
S-TRANSFERASE, MU 7
(Mus
musculus) 		3 / 3 THR A 207
SER A 208
ARG A 209
 None
 0.60A 3phnA-2dc5A:
undetectable		 3phnA-2dc5A:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_C_MXMC606_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2dc5 GLUTATHIONE
S-TRANSFERASE, MU 7
(Mus
musculus) 		3 / 3 LEU A  28
ARG A  25
MET A 215
 None
 0.99A 4m11C-2dc5A:
undetectable		 4m11C-2dc5A:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MBS_B_MRVB1101_2
(CHIMERA PROTEIN OF
C-C CHEMOKINE
RECEPTOR TYPE 5 AND
RUBREDOXIN)		 2dc5 GLUTATHIONE
S-TRANSFERASE, MU 7
(Mus
musculus) 		4 / 5 TYR A  40
THR A  31
LEU A  87
THR A  78
 None
 1.50A 4mbsB-2dc5A:
undetectable		 4mbsB-2dc5A:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UY8_7_TRP71002_0
(TRYPTOPHANASE)		 2dc5 GLUTATHIONE
S-TRANSFERASE, MU 7
(Mus
musculus) 		4 / 4 ILE A 106
ASN A 109
ILE A 166
VAL A 163
 None
 0.98A 4uy87-2dc5A:
undetectable		 4uy87-2dc5A:
7.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_A_SORA1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 2dc5 GLUTATHIONE
S-TRANSFERASE, MU 7
(Mus
musculus) 		4 / 7 ARG A  25
PHE A 216
ARG A 173
TYR A  14
 None
 1.12A 5a06A-2dc5A:
undetectable		 5a06A-2dc5A:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_C_SORC1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 2dc5 GLUTATHIONE
S-TRANSFERASE, MU 7
(Mus
musculus) 		4 / 7 ARG A  25
PHE A 216
ARG A 173
TYR A  14
 None
 1.13A 5a06C-2dc5A:
undetectable		 5a06C-2dc5A:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_D_SORD1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 2dc5 GLUTATHIONE
S-TRANSFERASE, MU 7
(Mus
musculus) 		4 / 7 ARG A  25
PHE A 216
ARG A 173
TYR A  14
 None
 1.13A 5a06D-2dc5A:
undetectable		 5a06D-2dc5A:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_E_SORE1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 2dc5 GLUTATHIONE
S-TRANSFERASE, MU 7
(Mus
musculus) 		4 / 7 ARG A  25
PHE A 216
ARG A 173
TYR A  14
 None
 1.14A 5a06E-2dc5A:
undetectable		 5a06E-2dc5A:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_F_SORF1343_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 2dc5 GLUTATHIONE
S-TRANSFERASE, MU 7
(Mus
musculus) 		4 / 7 ARG A  25
PHE A 216
ARG A 173
TYR A  14
 None
 1.11A 5a06F-2dc5A:
undetectable		 5a06F-2dc5A:
18.59