SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2dck'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FIQ_C_SALC1335_1
(XANTHINE OXIDASE)		 2dck XYLANASE J
(Bacillus
sp.
41M-1) 		4 / 8 LEU A 258
PHE A 284
LEU A 236
ALA A 268
 None
 0.86A 1fiqC-2dckA:
undetectable		 1fiqC-2dckA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C2B_E_SAME500_0
(THREONINE SYNTHASE
1, CHLOROPLASTIC)		 2dck XYLANASE J
(Bacillus
sp.
41M-1) 		5 / 11 GLY A  25
SER A  26
PHE A  47
LEU A  46
ASP A  20
 None
 1.21A 2c2bE-2dckA:
0.0
2c2bF-2dckA:
0.0		 2c2bE-2dckA:
22.33
2c2bF-2dckA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LB3_B_4CHB192_0
(DEHALOPEROXIDASE A)		 2dck XYLANASE J
(Bacillus
sp.
41M-1) 		4 / 6 PHE A  94
PHE A 162
HIS A 161
VAL A  83
 None
 1.31A 3lb3B-2dckA:
undetectable		 3lb3B-2dckA:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M6W_A_SAMA465_0
(RRNA METHYLASE)		 2dck XYLANASE J
(Bacillus
sp.
41M-1) 		5 / 12 GLY A 276
GLY A 275
VAL A 310
VAL A 234
LEU A 321
 None
 1.08A 3m6wA-2dckA:
undetectable		 3m6wA-2dckA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BCS_A_ACTA1126_0
(CHIMERIC AVIDIN)		 2dck XYLANASE J
(Bacillus
sp.
41M-1) 		4 / 4 THR A 139
GLN A 141
ARG A 128
THR A 126
 None
 1.33A 4bcsA-2dckA:
0.0		 4bcsA-2dckA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_A_ACTA609_0
(NADH DEHYDROGENASE,
PUTATIVE)		 2dck XYLANASE J
(Bacillus
sp.
41M-1) 		3 / 3 VAL A  42
SER A  40
TRP A  39
 None
 0.97A 5jwaA-2dckA:
undetectable		 5jwaA-2dckA:
20.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TZO_A_7V7A202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 2dck XYLANASE J
(Bacillus
sp.
41M-1) 		5 / 12 TRP A  86
TYR A  95
PRO A 132
TRP A 144
GLY A 184
 None
 0.80A 5tzoA-2dckA:
25.6		 5tzoA-2dckA:
31.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TZO_B_7V7B201_2
(ENDO-1,4-BETA-XYLANA
SE A)		 2dck XYLANASE J
(Bacillus
sp.
41M-1) 		3 / 3 ARG A 128
PRO A 132
TYR A 185
 None
 0.88A 5tzoB-2dckA:
25.6		 5tzoB-2dckA:
31.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TZO_B_7V7B202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 2dck XYLANASE J
(Bacillus
sp.
41M-1) 		4 / 8 TYR A 124
ARG A 128
GLN A 142
TRP A 144
 None
 0.82A 5tzoB-2dckA:
25.6		 5tzoB-2dckA:
31.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TZO_B_7V7B202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 2dck XYLANASE J
(Bacillus
sp.
41M-1) 		4 / 8 TYR A 124
THR A 126
ARG A 128
GLN A 142
 None
 1.19A 5tzoB-2dckA:
25.6		 5tzoB-2dckA:
31.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TZO_C_7V7C201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 2dck XYLANASE J
(Bacillus
sp.
41M-1) 		5 / 12 TRP A  86
TYR A  95
PRO A 132
TRP A 144
GLY A 184
 None
 0.83A 5tzoC-2dckA:
25.5		 5tzoC-2dckA:
31.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JMJ_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 2dck XYLANASE J
(Bacillus
sp.
41M-1) 		4 / 5 GLY A 101
THR A 102
SER A 188
SER A 187
 None
 0.88A 6jmjA-2dckA:
undetectable		 6jmjA-2dckA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JNH_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 2dck XYLANASE J
(Bacillus
sp.
41M-1) 		4 / 7 GLY A 101
THR A 102
SER A 188
SER A 187
 None
 0.86A 6jnhA-2dckA:
undetectable		 6jnhA-2dckA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JOG_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 2dck XYLANASE J
(Bacillus
sp.
41M-1) 		4 / 6 GLY A 101
THR A 102
SER A 188
SER A 187
 None
 0.87A 6jogA-2dckA:
undetectable		 6jogA-2dckA:
17.82