SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2dct'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FMJ_A_RTLA401_0
(RETINOL DEHYDRATASE)		 2dct HYPOTHETICAL PROTEIN
TTHA0104
(Thermus
thermophilus) 		5 / 11 TYR A  53
LEU A   6
HIS A  85
MET A  17
ILE A  20
 None
 1.25A 1fmjA-2dctA:
0.0		 1fmjA-2dctA:
13.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FMJ_B_RTLB501_0
(RETINOL DEHYDRATASE)		 2dct HYPOTHETICAL PROTEIN
TTHA0104
(Thermus
thermophilus) 		5 / 10 TYR A  53
LEU A   6
HIS A  85
MET A  17
ILE A  20
 None
 1.28A 1fmjB-2dctA:
0.0		 1fmjB-2dctA:
13.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA602_0
(THIOCYANATE
DEHYDROGENASE)		 2dct HYPOTHETICAL PROTEIN
TTHA0104
(Thermus
thermophilus) 		3 / 3 LYS A  51
HIS A  46
HIS A  85
 None
 1.39A 5oexA-2dctA:
undetectable		 5oexA-2dctA:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_B_CUB602_0
(THIOCYANATE
DEHYDROGENASE)		 2dct HYPOTHETICAL PROTEIN
TTHA0104
(Thermus
thermophilus) 		3 / 3 LYS A  51
HIS A  46
HIS A  85
 None
 1.40A 5oexB-2dctA:
undetectable		 5oexB-2dctA:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_C_CUC603_0
(THIOCYANATE
DEHYDROGENASE)		 2dct HYPOTHETICAL PROTEIN
TTHA0104
(Thermus
thermophilus) 		3 / 3 LYS A  51
HIS A  46
HIS A  85
 None
 1.40A 5oexC-2dctA:
undetectable		 5oexC-2dctA:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_D_CUD603_0
(THIOCYANATE
DEHYDROGENASE)		 2dct HYPOTHETICAL PROTEIN
TTHA0104
(Thermus
thermophilus) 		3 / 3 LYS A  51
HIS A  46
HIS A  85
 None
 1.36A 5oexD-2dctA:
undetectable		 5oexD-2dctA:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BTX_A_EDTA503_0
(SOLUTE CARRIER
FAMILY 39
(IRON-REGULATED
TRANSPORTER))		 2dct HYPOTHETICAL PROTEIN
TTHA0104
(Thermus
thermophilus) 		4 / 7 SER A  49
HIS A  46
GLY A  48
LEU A  29
 None
 1.10A 6btxA-2dctA:
undetectable		 6btxA-2dctA:
12.87