SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2dd7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P91_A_SAMA1401_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE A)		 2dd7 GREEN FLUORESCENT
PROTEIN
(Chiridius
poppei) 		5 / 11 LEU A  95
GLY A 118
GLY A  93
ILE A 125
LEU A  21
 None
 1.17A 1p91A-2dd7A:
undetectable		 1p91A-2dd7A:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X91_A_LPRA1615_2
(ANGIOTENSIN
CONVERTING ENZYME)		 2dd7 GREEN FLUORESCENT
PROTEIN
(Chiridius
poppei) 		3 / 3 SER A  63
THR A  68
PHE A 174
 None
 0.75A 2x91A-2dd7A:
undetectable		 2x91A-2dd7A:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZBU_D_ADND504_1
(UNCHARACTERIZED
CONSERVED PROTEIN)		 2dd7 GREEN FLUORESCENT
PROTEIN
(Chiridius
poppei) 		3 / 3 PHE A 119
ASN A  15
PHE A 126
 None
 0.89A 2zbuD-2dd7A:
undetectable		 2zbuD-2dd7A:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HB6_A_DXCA75_0
(PPCA)		 2dd7 GREEN FLUORESCENT
PROTEIN
(Chiridius
poppei) 		4 / 8 LEU A  73
LYS A   5
ILE A   6
PHE A   4
 None
 0.86A 4hb6A-2dd7A:
undetectable		 4hb6A-2dd7A:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HB8_A_DXCA75_0
(PPCA)		 2dd7 GREEN FLUORESCENT
PROTEIN
(Chiridius
poppei) 		4 / 8 LEU A  73
LYS A   5
ILE A   6
PHE A   4
 None
 0.83A 4hb8A-2dd7A:
undetectable		 4hb8A-2dd7A:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_A_ADNA401_2
(ADENOSINE KINASE)		 2dd7 GREEN FLUORESCENT
PROTEIN
(Chiridius
poppei) 		4 / 4 LEU A  43
SER A  46
LEU A  14
LEU A  21
 None
 1.04A 4n09A-2dd7A:
undetectable		 4n09A-2dd7A:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R20_A_AERA602_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)		 2dd7 GREEN FLUORESCENT
PROTEIN
(Chiridius
poppei) 		4 / 8 ALA A  44
ILE A 115
GLU A  17
GLY A  16
 None
 0.84A 4r20A-2dd7A:
undetectable		 4r20A-2dd7A:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE2_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2dd7 GREEN FLUORESCENT
PROTEIN
(Chiridius
poppei) 		4 / 5 ALA A 153
TYR A 152
HIS A 198
PRO A 135
 None
CR2  A  56 ( 4.7A)
None
None
 1.29A 4ze2A-2dd7A:
undetectable		 4ze2A-2dd7A:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTI_F_LFXF101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 2dd7 GREEN FLUORESCENT
PROTEIN
(Chiridius
poppei) 		4 / 5 ARG A  31
GLY A  30
THR A   3
GLU A  28
 None
 1.15A 5btiC-2dd7A:
undetectable
5btiD-2dd7A:
undetectable		 5btiC-2dd7A:
14.99
5btiD-2dd7A:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESG_A_1YNA701_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2dd7 GREEN FLUORESCENT
PROTEIN
(Chiridius
poppei) 		5 / 12 TYR A 101
PHE A  45
ILE A 125
PHE A  19
GLY A 116
 CR2  A  56 ( 4.5A)
None
None
None
None
 1.36A 5esgA-2dd7A:
undetectable		 5esgA-2dd7A:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JLC_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2dd7 GREEN FLUORESCENT
PROTEIN
(Chiridius
poppei) 		5 / 12 ALA A 155
TYR A  59
PHE A 182
ILE A  71
TYR A  72
 None
CR2  A  56 ( 4.4A)
None
None
None
 1.16A 5jlcA-2dd7A:
undetectable		 5jlcA-2dd7A:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7P_B_9SCB601_1
(SERUM ALBUMIN)		 2dd7 GREEN FLUORESCENT
PROTEIN
(Chiridius
poppei) 		4 / 6 ASN A  15
PHE A 126
TYR A 164
LEU A  95
 None
 1.28A 6a7pB-2dd7A:
undetectable		 6a7pB-2dd7A:
15.21