SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2de0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I7Z_A_COCA301_1
(CHIMERA OF IG KAPPA
CHAIN: HUMAN
CONSTANT REGION AND
MOUSE VARIABLE
REGION)		 2de0 ALPHA-(1,6)-FUCOSYLT
RANSFERASE
(Homo
sapiens) 		4 / 8 LEU X 306
LEU X 316
GLU X 477
TRP X 326
 None
 0.77A 1i7zA-2de0X:
undetectable		 1i7zA-2de0X:
15.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7T_F_5FWF1001_1
(SUPEROXIDE DISMUTASE
[CU-ZN])		 2de0 ALPHA-(1,6)-FUCOSYLT
RANSFERASE
(Homo
sapiens) 		4 / 6 GLU X 183
PRO X 484
LYS X 185
GLU X 181
 None
 1.24A 4a7tF-2de0X:
undetectable		 4a7tF-2de0X:
15.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7U_A_ALEA1001_1
(SUPEROXIDE DISMUTASE
[CU-ZN])		 2de0 ALPHA-(1,6)-FUCOSYLT
RANSFERASE
(Homo
sapiens) 		4 / 6 GLU X 183
PRO X 484
LYS X 185
GLU X 181
 None
 1.26A 4a7uA-2de0X:
0.0		 4a7uA-2de0X:
15.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTR_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 2de0 ALPHA-(1,6)-FUCOSYLT
RANSFERASE
(Homo
sapiens) 		5 / 11 PHE X 467
ASP X 495
ILE X 496
TYR X 476
TYR X 382
 None
 1.47A 4rtrA-2de0X:
undetectable		 4rtrA-2de0X:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G5G_C_ACTC1740_0
(PUTATIVE XANTHINE
DEHYDROGENASE YAGS
FAD-BINDING SUBUNIT)		 2de0 ALPHA-(1,6)-FUCOSYLT
RANSFERASE
(Homo
sapiens) 		4 / 4 VAL X 474
GLU X 477
GLY X 221
LEU X 224
 None
 1.37A 5g5gC-2de0X:
undetectable		 5g5gC-2de0X:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HI2_A_BAXA801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 2de0 ALPHA-(1,6)-FUCOSYLT
RANSFERASE
(Homo
sapiens) 		5 / 8 VAL X 359
VAL X 474
ILE X 451
ASP X 453
PHE X 456
 None
 1.39A 5hi2A-2de0X:
undetectable		 5hi2A-2de0X:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HRQ_E_IPHE101_0
(INSULIN A-CHAIN
INSULIN B-CHAIN)		 2de0 ALPHA-(1,6)-FUCOSYLT
RANSFERASE
(Homo
sapiens) 		4 / 7 ILE X 427
HIS X 455
LEU X 457
ALA X 460
 None
 0.98A 5hrqE-2de0X:
undetectable
5hrqF-2de0X:
undetectable
5hrqJ-2de0X:
undetectable		 5hrqE-2de0X:
4.65
5hrqF-2de0X:
5.64
5hrqJ-2de0X:
5.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_0
(TUBULIN BETA-2B
CHAIN)		 2de0 ALPHA-(1,6)-FUCOSYLT
RANSFERASE
(Homo
sapiens) 		5 / 11 VAL X 262
SER X 263
THR X 265
TYR X 334
LEU X 335
 None
 1.25A 5jh7B-2de0X:
undetectable		 5jh7B-2de0X:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_D_6K9D502_0
(TUBULIN BETA-2B
CHAIN)		 2de0 ALPHA-(1,6)-FUCOSYLT
RANSFERASE
(Homo
sapiens) 		5 / 11 VAL X 262
SER X 263
THR X 265
TYR X 334
LEU X 335
 None
 1.28A 5jh7D-2de0X:
2.5		 5jh7D-2de0X:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_A_ERMA2001_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 2de0 ALPHA-(1,6)-FUCOSYLT
RANSFERASE
(Homo
sapiens) 		5 / 12 LEU X 457
ASP X 453
VAL X 362
ALA X 349
LEU X 414
 None
 0.84A 5tudA-2de0X:
1.9		 5tudA-2de0X:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_A_RITA602_2
(CYTOCHROME P450 3A5)		 2de0 ALPHA-(1,6)-FUCOSYLT
RANSFERASE
(Homo
sapiens) 		3 / 3 ARG X 365
PHE X 456
LEU X 463
 None
 0.87A 5veuA-2de0X:
undetectable		 5veuA-2de0X:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XOO_A_ADNA506_1
(GLYCOSAMINOGLYCAN
XYLOSYLKINASE)		 2de0 ALPHA-(1,6)-FUCOSYLT
RANSFERASE
(Homo
sapiens) 		4 / 6 LEU X 406
LYS X 420
GLU X 416
LEU X 413
 None
 1.34A 5xooA-2de0X:
undetectable		 5xooA-2de0X:
8.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZSF_A_6T0A910_0
(TOLL-LIKE RECEPTOR 7)		 2de0 ALPHA-(1,6)-FUCOSYLT
RANSFERASE
(Homo
sapiens) 		4 / 7 THR X 408
ASP X 410
LEU X 413
TYR X 382
 None
 1.01A 5zsfA-2de0X:
undetectable
5zsfB-2de0X:
undetectable		 5zsfA-2de0X:
9.63
5zsfB-2de0X:
9.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA607_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 2de0 ALPHA-(1,6)-FUCOSYLT
RANSFERASE
(Homo
sapiens) 		4 / 4 GLY X 142
ARG X 147
ASN X 143
LEU X 145
 None
 1.50A 6b58A-2de0X:
5.8		 6b58A-2de0X:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_B_RFPB502_2
(RIFAMPIN
MONOOXYGENASE)		 2de0 ALPHA-(1,6)-FUCOSYLT
RANSFERASE
(Homo
sapiens) 		4 / 6 GLN X 480
VAL X 319
MET X 232
ARG X 337
 None
 1.32A 6brdB-2de0X:
undetectable		 6brdB-2de0X:
13.04