SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2dfj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_A_CHDA1502_0
(FERROCHELATASE)		 2dfj DIADENOSINETETRAPHOS
PHATASE
(Shigella
flexneri) 		4 / 8 LEU A  38
PRO A  27
VAL A  59
GLY A  56
 None
 0.96A 1hrkA-2dfjA:
undetectable		 1hrkA-2dfjA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_B_CHDB2502_0
(FERROCHELATASE)		 2dfj DIADENOSINETETRAPHOS
PHATASE
(Shigella
flexneri) 		4 / 8 LEU A  38
PRO A  27
VAL A  59
GLY A  56
 None
 0.96A 1hrkB-2dfjA:
undetectable		 1hrkB-2dfjA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_A_ACTA1871_0
(FPRA)		 2dfj DIADENOSINETETRAPHOS
PHATASE
(Shigella
flexneri) 		4 / 7 PHE A 211
PRO A 200
ALA A 242
PHE A 225
 None
 1.14A 1lqtA-2dfjA:
undetectable		 1lqtA-2dfjA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_A_ACTA1428_0
(FPRA)		 2dfj DIADENOSINETETRAPHOS
PHATASE
(Shigella
flexneri) 		4 / 7 PHE A 211
PRO A 200
ALA A 242
PHE A 225
 None
 1.15A 1lquA-2dfjA:
undetectable		 1lquA-2dfjA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE1_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 2dfj DIADENOSINETETRAPHOS
PHATASE
(Shigella
flexneri) 		3 / 3 ASP A  37
HIS A  66
HIS A  10
 MN  A1001 ( 3.0A)
None
MN  A1002 (-3.3A)
 0.63A 1oe1A-2dfjA:
undetectable		 1oe1A-2dfjA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE3_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 2dfj DIADENOSINETETRAPHOS
PHATASE
(Shigella
flexneri) 		3 / 3 ASP A  37
HIS A  66
HIS A  10
 MN  A1001 ( 3.0A)
None
MN  A1002 (-3.3A)
 0.63A 1oe3A-2dfjA:
undetectable		 1oe3A-2dfjA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2dfj DIADENOSINETETRAPHOS
PHATASE
(Shigella
flexneri) 		4 / 8 LEU A  38
PRO A  27
VAL A  59
GLY A  56
 None
 0.93A 2po5B-2dfjA:
undetectable		 2po5B-2dfjA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_A_CUA1338_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 2dfj DIADENOSINETETRAPHOS
PHATASE
(Shigella
flexneri) 		3 / 3 ASP A  37
HIS A  66
HIS A  10
 MN  A1001 ( 3.0A)
None
MN  A1002 (-3.3A)
 0.64A 2xxgA-2dfjA:
undetectable		 2xxgA-2dfjA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_C_CUC1339_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 2dfj DIADENOSINETETRAPHOS
PHATASE
(Shigella
flexneri) 		3 / 3 ASP A  37
HIS A  66
HIS A  10
 MN  A1001 ( 3.0A)
None
MN  A1002 (-3.3A)
 0.64A 2xxgC-2dfjA:
undetectable		 2xxgC-2dfjA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AXZ_A_ADNA401_1
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 2dfj DIADENOSINETETRAPHOS
PHATASE
(Shigella
flexneri) 		5 / 12 LEU A 231
SER A 230
GLY A 246
SER A 199
GLY A 233
 None
 0.73A 3axzA-2dfjA:
undetectable		 3axzA-2dfjA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_B_RBVB601_1
(RNA POLYMERASE)		 2dfj DIADENOSINETETRAPHOS
PHATASE
(Shigella
flexneri) 		5 / 9 ASP A  37
THR A 181
ASN A  65
ASP A  67
LEU A 143
 MN  A1001 ( 3.0A)
None
MN  A1001 (-2.6A)
None
None
 1.48A 3sfuB-2dfjA:
undetectable		 3sfuB-2dfjA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HP1_A_PPFA602_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 2dfj DIADENOSINETETRAPHOS
PHATASE
(Shigella
flexneri) 		4 / 6 ARG A  41
ASP A 244
GLY A 246
ASP A   8
 None
MN  A1002 ( 4.5A)
None
MN  A1002 (-3.2A)
 1.08A 5hp1A-2dfjA:
undetectable		 5hp1A-2dfjA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_A_ROCA101_1
(PROTEASE PR5-SQV)		 2dfj DIADENOSINETETRAPHOS
PHATASE
(Shigella
flexneri) 		5 / 9 ASP A 244
GLY A 122
ILE A 123
THR A 236
PRO A 237
 MN  A1002 ( 4.5A)
None
None
None
None
 1.19A 5kr2A-2dfjA:
undetectable		 5kr2A-2dfjA:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_C_ROCC101_1
(PROTEASE PR5-SQV)		 2dfj DIADENOSINETETRAPHOS
PHATASE
(Shigella
flexneri) 		5 / 9 ASP A 244
GLY A 122
ILE A 123
THR A 236
PRO A 237
 MN  A1002 ( 4.5A)
None
None
None
None
 1.27A 5kr2C-2dfjA:
undetectable		 5kr2C-2dfjA:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NCD_D_ACTD301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 2dfj DIADENOSINETETRAPHOS
PHATASE
(Shigella
flexneri) 		4 / 4 ASP A  37
HIS A 120
HIS A 227
HIS A  66
 MN  A1001 ( 3.0A)
MN  A1001 (-3.4A)
MN  A1001 (-3.2A)
None
 1.49A 5ncdD-2dfjA:
undetectable		 5ncdD-2dfjA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_A_SAMA501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 2dfj DIADENOSINETETRAPHOS
PHATASE
(Shigella
flexneri) 		5 / 11 LEU A  38
GLY A   7
VAL A  62
ARG A  60
GLN A 109
 None
 1.12A 5o96A-2dfjA:
undetectable
5o96B-2dfjA:
undetectable		 5o96A-2dfjA:
24.21
5o96B-2dfjA:
24.21