SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2dg0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_E_MK1E902_2
(POL POLYPROTEIN)		 2dg0 DRP35
(Staphylococcus
aureus) 		3 / 3 ASP A 214
ILE A 178
VAL A 141
 None
 0.64A 2avvD-2dg0A:
undetectable		 2avvD-2dg0A:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		 2dg0 DRP35
(Staphylococcus
aureus) 		5 / 12 ARG A  80
LEU A  47
LEU A 309
ILE A  71
ILE A  78
 None
 1.00A 2bxqA-2dg0A:
undetectable		 2bxqA-2dg0A:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CPP_A_CAMA422_0
(CYTOCHROME P450-CAM)		 2dg0 DRP35
(Staphylococcus
aureus) 		4 / 7 TYR A 227
THR A 199
LEU A 257
VAL A 248
 None
 0.95A 2cppA-2dg0A:
undetectable		 2cppA-2dg0A:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_B_KLNB1498_1
(CYTOCHROME P450 3A4)		 2dg0 DRP35
(Staphylococcus
aureus) 		5 / 9 ARG A 205
LEU A 196
ILE A 178
ALA A 223
GLY A 263
 None
 1.19A 2v0mB-2dg0A:
undetectable		 2v0mB-2dg0A:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKW_A_P1BA1478_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2dg0 DRP35
(Staphylococcus
aureus) 		4 / 7 ILE A 266
GLN A 268
ALA A  34
ILE A 296
 None
 0.77A 2xkwA-2dg0A:
undetectable		 2xkwA-2dg0A:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KL3_A_DHIA403_0
(GLUCURONOXYLANASE
XYNC)		 2dg0 DRP35
(Staphylococcus
aureus) 		4 / 4 GLY A 106
TYR A 104
GLY A 113
ASP A 130
 None
 0.99A 3kl3A-2dg0A:
undetectable		 3kl3A-2dg0A:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R0L_D_ACTD127_0
(PHOSPHOLIPASE A2 CB)		 2dg0 DRP35
(Staphylococcus
aureus) 		4 / 5 PHE A 101
ILE A 127
GLY A 147
HIS A  95
 None
 1.27A 3r0lD-2dg0A:
undetectable		 3r0lD-2dg0A:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4A_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 2dg0 DRP35
(Staphylococcus
aureus) 		4 / 8 TYR A 227
THR A 199
LEU A 257
VAL A 248
 None
 0.93A 4l4aA-2dg0A:
undetectable		 4l4aA-2dg0A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKW_A_198A1001_2
(ANDROGEN RECEPTOR)		 2dg0 DRP35
(Staphylococcus
aureus) 		4 / 7 ASN A  51
LEU A 309
LEU A 294
ILE A  71
 None
 1.02A 4okwA-2dg0A:
undetectable		 4okwA-2dg0A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q5M_A_ROCA1101_3
(PROTEASE)		 2dg0 DRP35
(Staphylococcus
aureus) 		3 / 3 ASP A 236
ASP A 138
ASN A  88
 None
 0.79A 4q5mA-2dg0A:
undetectable		 4q5mA-2dg0A:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y80_A_IREA402_0
(CYCLIN-G-ASSOCIATED
KINASE)		 2dg0 DRP35
(Staphylococcus
aureus) 		5 / 11 ALA A 188
ASP A 236
SER A 237
VAL A 312
ILE A 296
 None
 1.31A 5y80A-2dg0A:
undetectable		 5y80A-2dg0A:
14.15