SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2dg2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4S_A_TPVA201_2
(PROTEIN (HIV-1
PROTEASE))		 2dg2 APOLIPOPROTEIN A-I
BINDING PROTEIN
(Mus
musculus) 		4 / 8 GLY A 202
ILE A 203
PHE A 162
VAL A 166
 None
None
SO4  A1001 (-3.8A)
None
 0.80A 1d4sB-2dg2A:
undetectable		 1d4sB-2dg2A:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_A_SAMA2001_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 2dg2 APOLIPOPROTEIN A-I
BINDING PROTEIN
(Mus
musculus) 		5 / 12 LEU A 211
ASP A  39
VAL A  38
VAL A 233
TYR A 248
 None
 1.36A 2g70A-2dg2A:
3.8		 2g70A-2dg2A:
23.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKW_B_P1BB1475_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2dg2 APOLIPOPROTEIN A-I
BINDING PROTEIN
(Mus
musculus) 		4 / 6 LEU A 174
ILE A 157
ILE A 133
LEU A 136
 None
 0.90A 2xkwB-2dg2A:
undetectable		 2xkwB-2dg2A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_C_TFPC202_1
(PROTEIN S100-A4)		 2dg2 APOLIPOPROTEIN A-I
BINDING PROTEIN
(Mus
musculus) 		5 / 11 SER A 191
LEU A 207
SER A 186
ILE A  65
CYH A  97
 None
 1.35A 3ko0A-2dg2A:
undetectable
3ko0B-2dg2A:
undetectable
3ko0C-2dg2A:
undetectable
3ko0D-2dg2A:
undetectable		 3ko0A-2dg2A:
15.35
3ko0B-2dg2A:
15.35
3ko0C-2dg2A:
15.35
3ko0D-2dg2A:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_D_TFPD202_1
(PROTEIN S100-A4)		 2dg2 APOLIPOPROTEIN A-I
BINDING PROTEIN
(Mus
musculus) 		5 / 11 LEU A 207
SER A 186
ILE A  65
CYH A  97
SER A 191
 None
 1.34A 3ko0C-2dg2A:
undetectable
3ko0D-2dg2A:
undetectable
3ko0E-2dg2A:
undetectable
3ko0F-2dg2A:
undetectable		 3ko0C-2dg2A:
15.35
3ko0D-2dg2A:
15.35
3ko0E-2dg2A:
15.35
3ko0F-2dg2A:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_E_TFPE202_1
(PROTEIN S100-A4)		 2dg2 APOLIPOPROTEIN A-I
BINDING PROTEIN
(Mus
musculus) 		5 / 11 SER A 191
LEU A 207
SER A 186
ILE A  65
CYH A  97
 None
 1.35A 3ko0C-2dg2A:
undetectable
3ko0D-2dg2A:
undetectable
3ko0E-2dg2A:
undetectable
3ko0F-2dg2A:
undetectable		 3ko0C-2dg2A:
15.35
3ko0D-2dg2A:
15.35
3ko0E-2dg2A:
15.35
3ko0F-2dg2A:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_F_TFPF202_1
(PROTEIN S100-A4)		 2dg2 APOLIPOPROTEIN A-I
BINDING PROTEIN
(Mus
musculus) 		5 / 11 LEU A 207
SER A 186
ILE A  65
CYH A  97
SER A 191
 None
 1.37A 3ko0E-2dg2A:
undetectable
3ko0F-2dg2A:
undetectable
3ko0G-2dg2A:
undetectable
3ko0H-2dg2A:
undetectable		 3ko0E-2dg2A:
15.35
3ko0F-2dg2A:
15.35
3ko0G-2dg2A:
15.35
3ko0H-2dg2A:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_H_TFPH202_1
(PROTEIN S100-A4)		 2dg2 APOLIPOPROTEIN A-I
BINDING PROTEIN
(Mus
musculus) 		5 / 12 LEU A 207
SER A 186
ILE A  65
CYH A  97
SER A 191
 None
 1.33A 3ko0G-2dg2A:
undetectable
3ko0H-2dg2A:
undetectable
3ko0I-2dg2A:
undetectable
3ko0J-2dg2A:
undetectable		 3ko0G-2dg2A:
15.35
3ko0H-2dg2A:
15.35
3ko0I-2dg2A:
15.35
3ko0J-2dg2A:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_N_TFPN202_1
(PROTEIN S100-A4)		 2dg2 APOLIPOPROTEIN A-I
BINDING PROTEIN
(Mus
musculus) 		5 / 11 SER A 191
LEU A 207
SER A 186
ILE A  65
CYH A  97
 None
 1.34A 3ko0K-2dg2A:
undetectable
3ko0L-2dg2A:
undetectable
3ko0M-2dg2A:
undetectable
3ko0N-2dg2A:
undetectable		 3ko0K-2dg2A:
15.35
3ko0L-2dg2A:
15.35
3ko0M-2dg2A:
15.35
3ko0N-2dg2A:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_O_TFPO202_1
(PROTEIN S100-A4)		 2dg2 APOLIPOPROTEIN A-I
BINDING PROTEIN
(Mus
musculus) 		5 / 11 LEU A 207
SER A 186
ILE A  65
CYH A  97
SER A 191
 None
 1.38A 3ko0O-2dg2A:
undetectable
3ko0P-2dg2A:
undetectable
3ko0Q-2dg2A:
undetectable
3ko0R-2dg2A:
undetectable		 3ko0O-2dg2A:
15.35
3ko0P-2dg2A:
15.35
3ko0Q-2dg2A:
15.35
3ko0R-2dg2A:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_Q_TFPQ202_1
(PROTEIN S100-A4)		 2dg2 APOLIPOPROTEIN A-I
BINDING PROTEIN
(Mus
musculus) 		5 / 10 SER A 191
LEU A 207
SER A 186
ILE A  65
CYH A  97
 None
 1.41A 3ko0O-2dg2A:
undetectable
3ko0P-2dg2A:
undetectable
3ko0Q-2dg2A:
undetectable
3ko0R-2dg2A:
undetectable		 3ko0O-2dg2A:
15.35
3ko0P-2dg2A:
15.35
3ko0Q-2dg2A:
15.35
3ko0R-2dg2A:
15.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ROX_A_TEPA266_1
(APOLIPOPROTEIN
A-I-BINDING PROTEIN)		 2dg2 APOLIPOPROTEIN A-I
BINDING PROTEIN
(Mus
musculus) 		4 / 8 ALA A  35
VAL A  38
ASP A  39
LEU A  42
 None
 0.82A 3roxA-2dg2A:
43.3		 3roxA-2dg2A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ROX_A_TEPA266_1
(APOLIPOPROTEIN
A-I-BINDING PROTEIN)		 2dg2 APOLIPOPROTEIN A-I
BINDING PROTEIN
(Mus
musculus) 		7 / 8 ALA A  35
VAL A  38
LEU A  42
ASP A 188
LEU A 211
THR A 212
LYS A 215
 None
 0.25A 3roxA-2dg2A:
43.3		 3roxA-2dg2A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ROZ_A_NCAA266_0
(APOLIPOPROTEIN
A-I-BINDING PROTEIN)		 2dg2 APOLIPOPROTEIN A-I
BINDING PROTEIN
(Mus
musculus) 		6 / 6 ASP A  39
LEU A  42
ALA A  57
ASP A  93
LEU A 211
THR A 212
 None
 0.36A 3rozA-2dg2A:
42.5		 3rozA-2dg2A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPC_B_SAMB401_0
(PAVINE
N-METHYLTRANSFERASE)		 2dg2 APOLIPOPROTEIN A-I
BINDING PROTEIN
(Mus
musculus) 		5 / 12 GLY A  94
GLY A  92
ASP A 155
VAL A 154
ALA A  57
 None
 1.14A 5kpcB-2dg2A:
4.0		 5kpcB-2dg2A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZY_A_CE3A1103_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 2dg2 APOLIPOPROTEIN A-I
BINDING PROTEIN
(Mus
musculus) 		4 / 8 THR A 222
PRO A 205
ASP A 188
GLY A 192
 None
 0.89A 5nzyA-2dg2A:
2.8		 5nzyA-2dg2A:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXM_A_SAMA402_0
(DIPHTHAMIDE
BIOSYNTHESIS ENZYME
DPH2)		 2dg2 APOLIPOPROTEIN A-I
BINDING PROTEIN
(Mus
musculus) 		5 / 12 LEU A  56
GLY A 230
VAL A 154
CYH A  61
ASP A 188
 None
 1.04A 6bxmA-2dg2A:
3.4		 6bxmA-2dg2A:
20.66