SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2dgj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N4F_A_ASRA140_0
(LYSOZYME C)		 2dgj HYPOTHETICAL PROTEIN
EBHA
(Staphylococcus
aureus) 		3 / 3 ASN A 202
ALA A 206
ASN A 242
 None
 0.69A 1n4fA-2dgjA:
undetectable		 1n4fA-2dgjA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PIW_A_T3A932_1
(ANDROGEN RECEPTOR)		 2dgj HYPOTHETICAL PROTEIN
EBHA
(Staphylococcus
aureus) 		5 / 6 LEU A 132
VAL A 183
LYS A 180
ILE A 169
ILE A 136
 None
 1.48A 2piwA-2dgjA:
undetectable		 2piwA-2dgjA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BUF_A_AEGA394_0
(BETA-SECRETASE 1)		 2dgj HYPOTHETICAL PROTEIN
EBHA
(Staphylococcus
aureus) 		4 / 5 ASP A 126
ILE A 169
ILE A  94
GLY A 127
 None
 0.97A 3bufA-2dgjA:
undetectable		 3bufA-2dgjA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS6_B_EPAB1_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2dgj HYPOTHETICAL PROTEIN
EBHA
(Staphylococcus
aureus) 		5 / 12 ASN A 137
GLY A 127
ALA A 128
SER A 131
GLY A 134
 None
 0.89A 3hs6B-2dgjA:
undetectable		 3hs6B-2dgjA:
16.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9S_A_BEZA264_0
(CARNITINYL-COA
DEHYDRATASE)		 2dgj HYPOTHETICAL PROTEIN
EBHA
(Staphylococcus
aureus) 		4 / 6 ALA A 122
ILE A  94
LEU A 102
ALA A  84
 None
 0.77A 3r9sA-2dgjA:
undetectable		 3r9sA-2dgjA:
24.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9S_C_BEZC264_0
(CARNITINYL-COA
DEHYDRATASE)		 2dgj HYPOTHETICAL PROTEIN
EBHA
(Staphylococcus
aureus) 		4 / 6 ALA A 122
ILE A  94
LEU A 102
ALA A  84
 None
 0.82A 3r9sC-2dgjA:
undetectable		 3r9sC-2dgjA:
24.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_C_RBVC601_1
(RNA POLYMERASE)		 2dgj HYPOTHETICAL PROTEIN
EBHA
(Staphylococcus
aureus) 		5 / 11 ARG A  23
ASP A  24
LEU A  77
GLY A 114
ASP A 113
 None
None
None
SO4  A2002 ( 3.8A)
None
 1.25A 3sfuC-2dgjA:
undetectable		 3sfuC-2dgjA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_A_LNLA701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2dgj HYPOTHETICAL PROTEIN
EBHA
(Staphylococcus
aureus) 		5 / 12 ASN A 137
GLY A 127
ALA A 128
SER A 131
GLY A 134
 None
 0.77A 4e1gA-2dgjA:
undetectable		 4e1gA-2dgjA:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD9_A_ADNA501_1
(NUPC FAMILY PROTEIN)		 2dgj HYPOTHETICAL PROTEIN
EBHA
(Staphylococcus
aureus) 		5 / 12 GLY A 134
GLN A 133
ALA A 135
VAL A 190
TYR A 159
 None
 1.23A 4pd9A-2dgjA:
undetectable		 4pd9A-2dgjA:
21.05