SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2dgo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CD2_A_FOLA307_1
(DIHYDROFOLATE
REDUCTASE)		 2dgo CYTOTOXIC
GRANULE-ASSOCIATED
RNA BINDING PROTEIN
1
(Mus
musculus) 		3 / 3 GLU A 133
ILE A 136
ARG A 156
 None
 0.79A 1cd2A-2dgoA:
undetectable		 1cd2A-2dgoA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J4V_C_SVRC301_1
(NUCLEOCAPSID PROTEIN)		 2dgo CYTOTOXIC
GRANULE-ASSOCIATED
RNA BINDING PROTEIN
1
(Mus
musculus) 		4 / 8 GLY A  83
MET A 139
PHE A  98
ILE A  94
 None
 1.00A 4j4vC-2dgoA:
undetectable		 4j4vC-2dgoA:
16.46