SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2dgr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MS9_A_STIA1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 2dgr RING FINGER AND KH
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		4 / 6 VAL A 154
VAL A 114
ILE A 130
ARG A 163
 None
 1.13A 3ms9A-2dgrA:
undetectable		 3ms9A-2dgrA:
15.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND7_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 2dgr RING FINGER AND KH
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		5 / 12 GLU A 166
HIS A 171
LEU A 174
ALA A 170
ARG A 132
 None
 1.16A 5nd7B-2dgrA:
undetectable		 5nd7B-2dgrA:
11.17