SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2dh7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PKK_A_2FAA501_2
(ADENOSINE KINASE)		 2dh7 NUCLEOLYSIN TIAR
(Homo
sapiens) 		4 / 4 ALA A 151
VAL A 143
PHE A 120
THR A 170
 None
 1.23A 2pkkA-2dh7A:
undetectable		 2pkkA-2dh7A:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZH_A_D2VA602_1
(CYTOCHROME P450 2R1)		 2dh7 NUCLEOLYSIN TIAR
(Homo
sapiens) 		5 / 12 THR A 170
PHE A 120
ALA A 126
ALA A 151
ILE A 108
 None
 1.04A 3czhA-2dh7A:
undetectable		 3czhA-2dh7A:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZH_B_D2VB602_1
(CYTOCHROME P450 2R1)		 2dh7 NUCLEOLYSIN TIAR
(Homo
sapiens) 		5 / 12 THR A 170
PHE A 120
ALA A 126
ALA A 151
ILE A 108
 None
 1.01A 3czhB-2dh7A:
undetectable		 3czhB-2dh7A:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DL9_B_V2HB602_0
(CYTOCHROME P450 2R1)		 2dh7 NUCLEOLYSIN TIAR
(Homo
sapiens) 		5 / 12 THR A 170
PHE A 120
ALA A 126
ALA A 151
ILE A 108
 None
 1.04A 3dl9B-2dh7A:
undetectable		 3dl9B-2dh7A:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J4V_C_SVRC301_1
(NUCLEOCAPSID PROTEIN)		 2dh7 NUCLEOLYSIN TIAR
(Homo
sapiens) 		4 / 8 GLY A 102
MET A 158
PHE A 117
ILE A 113
 None
 0.88A 4j4vC-2dh7A:
undetectable		 4j4vC-2dh7A:
16.32