SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2di3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OW9_A_HAEA502_1
(COLLAGENASE 3)		 2di3 BACTERIAL REGULATORY
PROTEINS, GNTR
FAMILY
(Corynebacterium
glutamicum) 		4 / 6 LEU A 141
HIS A 148
HIS A 218
HIS A 196
 None
ZN  A1002 (-3.3A)
ZN  A1002 (-3.3A)
ZN  A1002 (-3.3A)
 0.78A 2ow9A-2di3A:
undetectable		 2ow9A-2di3A:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_A_CHDA3_0
(FERROCHELATASE)		 2di3 BACTERIAL REGULATORY
PROTEINS, GNTR
FAMILY
(Corynebacterium
glutamicum) 		3 / 3 PRO A 183
LEU A 182
ARG A 178
 None
 0.85A 3aqiA-2di3A:
undetectable		 3aqiA-2di3A:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ERD_B_DESB800_1
(ESTROGEN RECEPTOR
ALPHA)		 2di3 BACTERIAL REGULATORY
PROTEINS, GNTR
FAMILY
(Corynebacterium
glutamicum) 		5 / 10 ALA A 123
GLU A 124
LEU A 203
LEU A 200
MET A 164
 None
 1.33A 3erdB-2di3A:
undetectable		 3erdB-2di3A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEC_A_HAEA272_1
(COLLAGENASE 3)		 2di3 BACTERIAL REGULATORY
PROTEINS, GNTR
FAMILY
(Corynebacterium
glutamicum) 		4 / 5 LEU A 141
HIS A 148
HIS A 218
HIS A 196
 None
ZN  A1002 (-3.3A)
ZN  A1002 (-3.3A)
ZN  A1002 (-3.3A)
 0.76A 3kecA-2di3A:
undetectable		 3kecA-2di3A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7B_A_HAEA1273_1
(COLLAGENASE 3)		 2di3 BACTERIAL REGULATORY
PROTEINS, GNTR
FAMILY
(Corynebacterium
glutamicum) 		4 / 6 LEU A 141
HIS A 148
HIS A 218
HIS A 196
 None
ZN  A1002 (-3.3A)
ZN  A1002 (-3.3A)
ZN  A1002 (-3.3A)
 0.82A 4a7bA-2di3A:
undetectable		 4a7bA-2di3A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RKU_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 2di3 BACTERIAL REGULATORY
PROTEINS, GNTR
FAMILY
(Corynebacterium
glutamicum) 		4 / 8 MET A 130
PHE A 140
ALA A 172
LEU A 141
 None
 1.04A 4rkuA-2di3A:
undetectable
4rkuJ-2di3A:
undetectable		 4rkuA-2di3A:
15.10
4rkuJ-2di3A:
12.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZN7_B_DESB600_1
(ESTROGEN RECEPTOR)		 2di3 BACTERIAL REGULATORY
PROTEINS, GNTR
FAMILY
(Corynebacterium
glutamicum) 		5 / 11 ALA A 123
GLU A 124
LEU A 203
LEU A 200
MET A 164
 None
 1.32A 4zn7B-2di3A:
undetectable		 4zn7B-2di3A:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L6E_B_ACTB401_0
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT
N6-ADENOSINE-METHYLT
RANSFERASE SUBUNIT
METTL14)		 2di3 BACTERIAL REGULATORY
PROTEINS, GNTR
FAMILY
(Corynebacterium
glutamicum) 		4 / 6 GLU A 106
LEU A 167
ARG A 168
ARG A 102
 None
 1.03A 5l6eA-2di3A:
undetectable
5l6eB-2di3A:
undetectable		 5l6eA-2di3A:
18.58
5l6eB-2di3A:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_A_BEZA502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 2di3 BACTERIAL REGULATORY
PROTEINS, GNTR
FAMILY
(Corynebacterium
glutamicum) 		4 / 6 VAL A 150
LEU A 203
LEU A 200
HIS A 196
 None
None
None
ZN  A1002 (-3.3A)
 0.69A 6e43A-2di3A:
undetectable		 6e43A-2di3A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_B_BEZB502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 2di3 BACTERIAL REGULATORY
PROTEINS, GNTR
FAMILY
(Corynebacterium
glutamicum) 		4 / 6 VAL A 150
LEU A 203
LEU A 200
HIS A 196
 None
None
None
ZN  A1002 (-3.3A)
 0.69A 6e43B-2di3A:
undetectable		 6e43B-2di3A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_C_BEZC502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 2di3 BACTERIAL REGULATORY
PROTEINS, GNTR
FAMILY
(Corynebacterium
glutamicum) 		4 / 6 VAL A 150
LEU A 203
LEU A 200
HIS A 196
 None
None
None
ZN  A1002 (-3.3A)
 0.69A 6e43C-2di3A:
undetectable		 6e43C-2di3A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_D_BEZD502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 2di3 BACTERIAL REGULATORY
PROTEINS, GNTR
FAMILY
(Corynebacterium
glutamicum) 		4 / 6 VAL A 150
LEU A 203
LEU A 200
HIS A 196
 None
None
None
ZN  A1002 (-3.3A)
 0.57A 6e43D-2di3A:
undetectable		 6e43D-2di3A:
22.28