SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2di8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GSS_A_EAAA212_1 (GLUTATHIONE S-TRANSFERASE P1-1)	2di8	FILAMIN-B (Homo sapiens)	4 / 7	PHE A 94 VAL A 96 ILE A 56 GLY A 20	None	0.94A	3gssA-2di8A: undetectable	3gssA-2di8A: 18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JB2_A_SAMA1102_1 (STRUCTURAL PROTEIN VP3)	2di8	FILAMIN-B (Homo sapiens)	3 / 3	ARG A 12 ASP A 38 ASP A 10	None	0.93A	3jb2A-2di8A: undetectable	3jb2A-2di8A: 6.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JB3_A_SAMA1102_1 (STRUCTURAL PROTEIN VP3)	2di8	FILAMIN-B (Homo sapiens)	3 / 3	ARG A 12 ASP A 38 ASP A 10	None	0.92A	3jb3A-2di8A: undetectable	3jb3A-2di8A: 6.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UCK_B_SAMB2409_0 (RNA-DIRECTED RNA POLYMERASE L)	2di8	FILAMIN-B (Homo sapiens)	5 / 12	GLY A 40 GLY A 7 ASP A 35 THR A 82 ALA A 11	None	1.13A	4uckB-2di8A: undetectable	4uckB-2di8A: 14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ERG_B_SAMB401_1 (TRNA (ADENINE(58)-N(1))-M ETHYLTRANSFERASE CATALYTIC SUBUNIT TRM61)	2di8	FILAMIN-B (Homo sapiens)	4 / 7	GLY A 9 GLY A 7 SER A 6 ASP A 38	None	0.68A	5ergB-2di8A: undetectable	5ergB-2di8A: 15.49

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3GSS_A_EAAA212_1","GLUTATHIONE S-TRANSFERASE P1-1","2di8","FILAMIN-B","Homo sapiens",4,"PHE A  94;VAL A  96;ILE A  56;GLY A  20","None","0.94A","3gssA-2di8A:undetectable","3gssA-2di8A:18.18"],["3JB2_A_SAMA1102_1","STRUCTURAL PROTEIN VP3","2di8","FILAMIN-B","Homo sapiens",3,"ARG A  12;ASP A  38;ASP A  10","None","0.93A","3jb2A-2di8A:undetectable","3jb2A-2di8A:6.74"],["3JB3_A_SAMA1102_1","STRUCTURAL PROTEIN VP3","2di8","FILAMIN-B","Homo sapiens",3,"ARG A  12;ASP A  38;ASP A  10","None","0.92A","3jb3A-2di8A:undetectable","3jb3A-2di8A:6.74"],["4UCK_B_SAMB2409_0","RNA-DIRECTED RNA POLYMERASE L","2di8","FILAMIN-B","Homo sapiens",5,"GLY A  40;GLY A   7;ASP A  35;THR A  82;ALA A  11","None","1.13A","4uckB-2di8A:undetectable","4uckB-2di8A:14.53"],["5ERG_B_SAMB401_1","TRNA (ADENINE(58)-N(1))-METHYLTRANSFERASE CATALYTIC SUBUNIT TRM61","2di8","FILAMIN-B","Homo sapiens",4,"GLY A   9;GLY A   7;SER A   6;ASP A  38","None","0.68A","5ergB-2di8A:undetectable","5ergB-2di8A:15.49"]]