SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2die'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_A_QPSA1001_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 2die AMYLASE
(Bacillus
sp.
(in:
Bacteria)) 		7 / 12 TYR A  58
LEU A 201
ASP A 236
ALA A 237
GLU A 266
HIS A 332
ASP A 333
 None
 0.67A 1dedA-2dieA:
26.1		 1dedA-2dieA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_B_QPSB1501_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 2die AMYLASE
(Bacillus
sp.
(in:
Bacteria)) 		7 / 12 TYR A  58
ARG A 234
ASP A 236
ALA A 237
GLU A 266
HIS A 332
ASP A 333
 None
 0.58A 1dedB-2dieA:
28.0		 1dedB-2dieA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQH_A_FLPA701_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 2die AMYLASE
(Bacillus
sp.
(in:
Bacteria)) 		6 / 12 VAL A  42
LEU A  34
GLY A  87
ALA A  88
SER A  91
LEU A  92
 None
 1.28A 1eqhA-2dieA:
undetectable		 1eqhA-2dieA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GAH_A_ACRA497_2
(GLUCOAMYLASE-471)		 2die AMYLASE
(Bacillus
sp.
(in:
Bacteria)) 		4 / 6 ALA A 300
TRP A 413
ARG A 359
LEU A 297
 None
 1.14A 1gahA-2dieA:
undetectable		 1gahA-2dieA:
21.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MXD_A_ACRA735_1
(ALPHA AMYLASE)		 2die AMYLASE
(Bacillus
sp.
(in:
Bacteria)) 		7 / 12 TRP A  15
TYR A  58
ARG A 234
ASP A 236
GLU A 266
TRP A 268
HIS A 332
 None
 1.00A 1mxdA-2dieA:
39.7		 1mxdA-2dieA:
31.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MXD_A_ACRA735_1
(ALPHA AMYLASE)		 2die AMYLASE
(Bacillus
sp.
(in:
Bacteria)) 		7 / 12 TRP A  15
TYR A  58
ARG A 234
ASP A 236
TRP A 268
HIS A 332
ASP A 333
 None
 0.98A 1mxdA-2dieA:
39.7		 1mxdA-2dieA:
31.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MXD_A_ACRA735_1
(ALPHA AMYLASE)		 2die AMYLASE
(Bacillus
sp.
(in:
Bacteria)) 		7 / 12 TRP A  15
TYR A  58
HIS A 107
ARG A 234
ASP A 236
HIS A 332
ASP A 333
 None
 0.59A 1mxdA-2dieA:
39.7		 1mxdA-2dieA:
31.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MXD_A_ACRA735_1
(ALPHA AMYLASE)		 2die AMYLASE
(Bacillus
sp.
(in:
Bacteria)) 		7 / 12 TYR A  58
ARG A 234
ASP A 236
LYS A 239
GLU A 266
TRP A 268
HIS A 332
 None
 1.12A 1mxdA-2dieA:
39.7		 1mxdA-2dieA:
31.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_5
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 2die AMYLASE
(Bacillus
sp.
(in:
Bacteria)) 		3 / 3 THR A 246
LEU A 250
VAL A 253
 None
 0.36A 1mz9E-2dieA:
undetectable		 1mz9E-2dieA:
6.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WG8_B_SAMB3141_1
(PREDICTED
S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 2die AMYLASE
(Bacillus
sp.
(in:
Bacteria)) 		3 / 3 HIS A 240
ASP A 166
ASN A 175
 None
 0.83A 1wg8B-2dieA:
undetectable		 1wg8B-2dieA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z2B_C_VLBC800_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)		 2die AMYLASE
(Bacillus
sp.
(in:
Bacteria)) 		4 / 8 VAL A 366
PRO A 364
TYR A 353
LEU A 357
 None
 1.02A 1z2bB-2dieA:
2.9		 1z2bB-2dieA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_E_MK1E902_2
(POL POLYPROTEIN)		 2die AMYLASE
(Bacillus
sp.
(in:
Bacteria)) 		3 / 3 ASP A 231
ILE A  39
VAL A 326
 None
 0.68A 2avvD-2dieA:
undetectable		 2avvD-2dieA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_A_DZPA2001_1
(SERUM ALBUMIN)		 2die AMYLASE
(Bacillus
sp.
(in:
Bacteria)) 		5 / 12 LEU A 230
TYR A 224
LEU A 228
VAL A  89
LEU A  85
 None
 1.14A 2bxfA-2dieA:
undetectable		 2bxfA-2dieA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DDW_B_PXLB1005_1
(PYRIDOXINE KINASE)		 2die AMYLASE
(Bacillus
sp.
(in:
Bacteria)) 		4 / 7 LEU A 426
THR A 414
HIS A 402
GLY A 468
 None
 1.02A 2ddwB-2dieA:
undetectable		 2ddwB-2dieA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OWC_A_ACRA600_1
(4-ALPHA-GLUCANOTRANS
FERASE)		 2die AMYLASE
(Bacillus
sp.
(in:
Bacteria)) 		5 / 11 TYR A  58
ASP A 236
HIS A 332
ASP A 333
TRP A  15
 None
 1.01A 2owcA-2dieA:
15.0		 2owcA-2dieA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OWW_A_ACRA600_1
(4-ALPHA-GLUCANOTRANS
FERASE)		 2die AMYLASE
(Bacillus
sp.
(in:
Bacteria)) 		5 / 11 TYR A  58
ASP A 236
HIS A 332
ASP A 333
TRP A  15
 None
 1.01A 2owwA-2dieA:
15.0		 2owwA-2dieA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_A_ACRA5044_1
(GLUCOSYLTRANSFERASE-
SI)		 2die AMYLASE
(Bacillus
sp.
(in:
Bacteria)) 		6 / 12 LEU A 201
ARG A 234
ASP A 236
ALA A 237
HIS A 332
ASP A 333
 None
 0.60A 3aicA-2dieA:
11.7		 3aicA-2dieA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_B_ACRB5044_1
(GLUCOSYLTRANSFERASE-
SI)		 2die AMYLASE
(Bacillus
sp.
(in:
Bacteria)) 		6 / 12 ARG A 234
ASP A 236
ALA A 237
GLU A 266
HIS A 332
ASP A 333
 None
 0.86A 3aicB-2dieA:
11.5		 3aicB-2dieA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_B_ACRB5044_1
(GLUCOSYLTRANSFERASE-
SI)		 2die AMYLASE
(Bacillus
sp.
(in:
Bacteria)) 		6 / 12 LEU A 201
ARG A 234
ASP A 236
ALA A 237
HIS A 332
ASP A 333
 None
 0.62A 3aicB-2dieA:
11.5		 3aicB-2dieA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_C_ACRC5044_1
(GLUCOSYLTRANSFERASE-
SI)		 2die AMYLASE
(Bacillus
sp.
(in:
Bacteria)) 		7 / 12 ARG A 234
ASP A 236
ALA A 237
GLU A 266
HIS A 332
ASP A 333
TYR A  58
 None
 0.85A 3aicC-2dieA:
11.7		 3aicC-2dieA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_D_ACRD5044_1
(GLUCOSYLTRANSFERASE-
SI)		 2die AMYLASE
(Bacillus
sp.
(in:
Bacteria)) 		6 / 12 ARG A 234
ASP A 236
ALA A 237
GLU A 266
HIS A 332
ASP A 333
 None
 0.88A 3aicD-2dieA:
11.7		 3aicD-2dieA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_D_ACRD5044_1
(GLUCOSYLTRANSFERASE-
SI)		 2die AMYLASE
(Bacillus
sp.
(in:
Bacteria)) 		6 / 12 LEU A 201
ARG A 234
ASP A 236
ALA A 237
HIS A 332
ASP A 333
 None
 0.66A 3aicD-2dieA:
11.7		 3aicD-2dieA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_E_ACRE5044_1
(GLUCOSYLTRANSFERASE-
SI)		 2die AMYLASE
(Bacillus
sp.
(in:
Bacteria)) 		6 / 12 ARG A 234
ASP A 236
ALA A 237
GLU A 266
HIS A 332
ASP A 333
 None
 0.86A 3aicE-2dieA:
11.7		 3aicE-2dieA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_E_ACRE5044_1
(GLUCOSYLTRANSFERASE-
SI)		 2die AMYLASE
(Bacillus
sp.
(in:
Bacteria)) 		6 / 12 LEU A 201
ARG A 234
ASP A 236
ALA A 237
HIS A 332
ASP A 333
 None
 0.65A 3aicE-2dieA:
11.7		 3aicE-2dieA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_F_ACRF5044_1
(GLUCOSYLTRANSFERASE-
SI)		 2die AMYLASE
(Bacillus
sp.
(in:
Bacteria)) 		6 / 12 LEU A 201
ARG A 234
ASP A 236
ALA A 237
HIS A 332
ASP A 333
 None
 0.64A 3aicF-2dieA:
11.6		 3aicF-2dieA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_G_ACRG5044_1
(GLUCOSYLTRANSFERASE-
SI)		 2die AMYLASE
(Bacillus
sp.
(in:
Bacteria)) 		6 / 12 LEU A 201
ARG A 234
ASP A 236
ALA A 237
HIS A 332
ASP A 333
 None
 0.62A 3aicG-2dieA:
11.7		 3aicG-2dieA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_H_ACRH5044_1
(GLUCOSYLTRANSFERASE-
SI)		 2die AMYLASE
(Bacillus
sp.
(in:
Bacteria)) 		6 / 12 ARG A 234
ASP A 236
ALA A 237
GLU A 266
HIS A 332
ASP A 333
 None
 0.89A 3aicH-2dieA:
11.7		 3aicH-2dieA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_H_ACRH5044_1
(GLUCOSYLTRANSFERASE-
SI)		 2die AMYLASE
(Bacillus
sp.
(in:
Bacteria)) 		6 / 12 LEU A 201
ARG A 234
ASP A 236
ALA A 237
HIS A 332
ASP A 333
 None
 0.69A 3aicH-2dieA:
11.7		 3aicH-2dieA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DVAD10_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 2die AMYLASE
(Bacillus
sp.
(in:
Bacteria)) 		3 / 3 GLY A 425
GLY A 399
GLY A 417
 None
 0.42A 3bogD-2dieA:
undetectable		 3bogD-2dieA:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8W_A_FLPA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 2die AMYLASE
(Bacillus
sp.
(in:
Bacteria)) 		5 / 12 VAL A  42
GLY A  87
ALA A  88
SER A  91
LEU A  92
 None
 1.01A 3n8wA-2dieA:
undetectable		 3n8wA-2dieA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Z_A_FLPA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 2die AMYLASE
(Bacillus
sp.
(in:
Bacteria)) 		5 / 12 VAL A  42
GLY A  87
ALA A  88
SER A  91
LEU A  92
 None
 0.93A 3n8zA-2dieA:
undetectable		 3n8zA-2dieA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGH_C_FLPC701_1
(CYCLOOXYGENASE-2)		 2die AMYLASE
(Bacillus
sp.
(in:
Bacteria)) 		5 / 12 VAL A  42
GLY A  87
ALA A  88
SER A  91
LEU A  92
 None
 0.86A 3pghC-2dieA:
undetectable		 3pghC-2dieA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RR3_A_FLRA700_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2die AMYLASE
(Bacillus
sp.
(in:
Bacteria)) 		5 / 12 VAL A  42
GLY A  87
ALA A  88
SER A  91
LEU A  92
 None
 0.96A 3rr3A-2dieA:
undetectable		 3rr3A-2dieA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RR3_B_FLRB700_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2die AMYLASE
(Bacillus
sp.
(in:
Bacteria)) 		5 / 12 VAL A  42
GLY A  87
ALA A  88
SER A  91
LEU A  92
 None
 0.96A 3rr3B-2dieA:
undetectable		 3rr3B-2dieA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZT_A_SAMA1472_1
(METHYLTRANSFERASE
WBDD)		 2die AMYLASE
(Bacillus
sp.
(in:
Bacteria)) 		3 / 3 GLN A 319
ASP A 403
GLN A 401
 None
 0.85A 4aztA-2dieA:
undetectable		 4aztA-2dieA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7N_A_ZMRA601_2
(NEURAMINIDASE)		 2die AMYLASE
(Bacillus
sp.
(in:
Bacteria)) 		3 / 3 ARG A 359
ARG A 415
TRP A 413
 None
 0.74A 4b7nA-2dieA:
undetectable		 4b7nA-2dieA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_C_ZMRC1470_2
(NEURAMINIDASE)		 2die AMYLASE
(Bacillus
sp.
(in:
Bacteria)) 		3 / 3 ARG A 359
ARG A 415
TRP A 413
 None
 0.85A 4cpzC-2dieA:
undetectable		 4cpzC-2dieA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_E_ZMRE1471_2
(NEURAMINIDASE)		 2die AMYLASE
(Bacillus
sp.
(in:
Bacteria)) 		3 / 3 ARG A 359
ARG A 415
TRP A 413
 None
 0.79A 4cpzE-2dieA:
undetectable		 4cpzE-2dieA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_F_ZMRF1470_2
(NEURAMINIDASE)		 2die AMYLASE
(Bacillus
sp.
(in:
Bacteria)) 		3 / 3 ARG A 359
ARG A 415
TRP A 413
 None
 0.74A 4cpzF-2dieA:
undetectable		 4cpzF-2dieA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_G_ZMRG1471_2
(NEURAMINIDASE)		 2die AMYLASE
(Bacillus
sp.
(in:
Bacteria)) 		3 / 3 ARG A 359
ARG A 415
TRP A 413
 None
 0.77A 4cpzG-2dieA:
undetectable		 4cpzG-2dieA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_H_ZMRH1470_2
(NEURAMINIDASE)		 2die AMYLASE
(Bacillus
sp.
(in:
Bacteria)) 		3 / 3 ARG A 359
ARG A 415
TRP A 413
 None
 0.78A 4cpzH-2dieA:
undetectable		 4cpzH-2dieA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PH9_A_IBPA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2die AMYLASE
(Bacillus
sp.
(in:
Bacteria)) 		5 / 10 VAL A  42
LEU A  34
GLY A  87
ALA A  88
LEU A  92
 None
 0.94A 4ph9A-2dieA:
undetectable		 4ph9A-2dieA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PH9_B_IBPB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2die AMYLASE
(Bacillus
sp.
(in:
Bacteria)) 		5 / 10 VAL A  42
LEU A  34
GLY A  87
ALA A  88
LEU A  92
 None
 0.95A 4ph9B-2dieA:
undetectable		 4ph9B-2dieA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE5_A_OBNA1104_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 2die AMYLASE
(Bacillus
sp.
(in:
Bacteria)) 		5 / 12 LEU A 293
GLU A 341
ALA A 352
PHE A 367
ILE A 356
 None
 1.28A 4xe5A-2dieA:
undetectable		 4xe5A-2dieA:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z53_F_TR6F101_1
(DNA TOPOISOMERASE 4
SUBUNIT B,DNA
TOPOISOMERASE 4
SUBUNIT A
E-SITE DNA)		 2die AMYLASE
(Bacillus
sp.
(in:
Bacteria)) 		4 / 6 GLY A 232
ASP A 231
GLY A 101
SER A 365
 None
 1.01A 4z53A-2dieA:
undetectable
4z53B-2dieA:
undetectable		 4z53A-2dieA:
19.83
4z53B-2dieA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CU6_A_ACTA403_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 2die AMYLASE
(Bacillus
sp.
(in:
Bacteria)) 		4 / 6 VAL A 288
ASP A 290
PRO A 292
ALA A 325
 None
 0.84A 5cu6A-2dieA:
undetectable		 5cu6A-2dieA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G5H_C_ACTC1743_0
(PUTATIVE XANTHINE
DEHYDROGENASE YAGR
MOLYBDENUM-BINDING
SUBUNIT
PUTATIVE XANTHINE
DEHYDROGENASE YAGT
IRON-SULFUR-BINDING
SUBUNIT)		 2die AMYLASE
(Bacillus
sp.
(in:
Bacteria)) 		4 / 5 LYS A 349
ASP A 370
PHE A 343
PRO A 380
 None
 1.41A 5g5hA-2dieA:
0.0
5g5hC-2dieA:
0.0		 5g5hA-2dieA:
18.78
5g5hC-2dieA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_A_ASCA1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 2die AMYLASE
(Bacillus
sp.
(in:
Bacteria)) 		4 / 6 HIS A  16
VAL A  56
TYR A  58
HIS A 332
 None
 1.48A 5kkzA-2dieA:
undetectable
5kkzG-2dieA:
undetectable		 5kkzA-2dieA:
20.70
5kkzG-2dieA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND4_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 2die AMYLASE
(Bacillus
sp.
(in:
Bacteria)) 		5 / 12 ASP A 308
LEU A 297
ALA A 300
SER A 303
PHE A 348
 None
 1.19A 5nd4B-2dieA:
3.2		 5nd4B-2dieA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OTR_A_ACTA402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 2die AMYLASE
(Bacillus
sp.
(in:
Bacteria)) 		4 / 5 VAL A 288
ASP A 290
PRO A 292
ALA A 325
 None
 0.87A 5otrA-2dieA:
undetectable		 5otrA-2dieA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_B_OAQB302_0
(SULFOTRANSFERASE)		 2die AMYLASE
(Bacillus
sp.
(in:
Bacteria)) 		5 / 12 PRO A  46
VAL A 104
ILE A 241
LEU A 250
THR A 246
 None
 1.24A 5tiwB-2dieA:
undetectable		 5tiwB-2dieA:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TQR_B_SAMB8009_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EZH2, POLYCOMB
PROTEIN SUZ12)		 2die AMYLASE
(Bacillus
sp.
(in:
Bacteria)) 		5 / 10 TYR A 371
VAL A  42
TYR A  12
TYR A 372
HIS A 332
 None
 1.40A 5tqrB-2dieA:
undetectable		 5tqrB-2dieA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJS_A_SALA603_0
(VICILIN-LIKE
ANTIMICROBIAL
PEPTIDES 2-2)		 2die AMYLASE
(Bacillus
sp.
(in:
Bacteria)) 		5 / 11 GLY A 258
MET A 261
ASN A 226
VAL A 253
PHE A 233
 None
 1.20A 5yjsA-2dieA:
undetectable		 5yjsA-2dieA:
10.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6AG0_A_ACRA605_0
(ALPHA-AMYLASE)		 2die AMYLASE
(Bacillus
sp.
(in:
Bacteria)) 		7 / 8 TYR A 160
GLY A 182
LYS A 185
ASP A 207
ASP A 209
HIS A 210
PRO A 211
 None
None
None
CA  A 778 (-2.9A)
None
None
None
 0.69A 6ag0A-2dieA:
64.2		 6ag0A-2dieA:
32.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6AG0_A_ACRA606_0
(ALPHA-AMYLASE)		 2die AMYLASE
(Bacillus
sp.
(in:
Bacteria)) 		6 / 7 GLY A 304
GLY A 305
GLY A 433
PRO A 434
GLY A 435
GLY A 476
 None
CA  A 780 (-4.2A)
None
None
None
None
 1.40A 6ag0A-2dieA:
64.2		 6ag0A-2dieA:
32.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6AG0_A_ACRA606_0
(ALPHA-AMYLASE)		 2die AMYLASE
(Bacillus
sp.
(in:
Bacteria)) 		7 / 7 GLY A 304
GLY A 305
TRP A 347
GLY A 433
PRO A 434
GLY A 476
GLY A 477
 None
CA  A 780 (-4.2A)
None
None
None
None
None
 0.40A 6ag0A-2dieA:
64.2		 6ag0A-2dieA:
32.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6AG0_A_ACRA608_0
(ALPHA-AMYLASE)		 2die AMYLASE
(Bacillus
sp.
(in:
Bacteria)) 		5 / 6 GLY A   7
THR A  40
GLN A  98
TYR A 100
TYR A 363
 None
 0.36A 6ag0A-2dieA:
43.8		 6ag0A-2dieA:
32.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6AG0_A_ACRA609_0
(ALPHA-AMYLASE)		 2die AMYLASE
(Bacillus
sp.
(in:
Bacteria)) 		7 / 7 LYS A  72
GLY A 110
TRP A 140
ASP A 166
TRP A 167
MET A 202
TYR A 203
 None
 0.32A 6ag0A-2dieA:
64.2		 6ag0A-2dieA:
32.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6AG0_A_ACRA610_0
(ALPHA-AMYLASE)		 2die AMYLASE
(Bacillus
sp.
(in:
Bacteria)) 		12 / 12 TRP A  15
TYR A  58
HIS A 107
GLU A 194
TYR A 198
LEU A 201
MET A 202
ASP A 236
LYS A 239
HIS A 240
HIS A 332
ASP A 333
 None
 0.53A 6ag0A-2dieA:
64.2		 6ag0A-2dieA:
32.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6AG0_C_ACRC605_0
(ALPHA-AMYLASE)		 2die AMYLASE
(Bacillus
sp.
(in:
Bacteria)) 		6 / 8 GLY A 182
LYS A 185
ASP A 207
ASP A 209
HIS A 210
PRO A 211
 None
None
CA  A 778 (-2.9A)
None
None
None
 0.73A 6ag0C-2dieA:
64.2		 6ag0C-2dieA:
32.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6AG0_C_ACRC605_0
(ALPHA-AMYLASE)		 2die AMYLASE
(Bacillus
sp.
(in:
Bacteria)) 		6 / 8 TYR A 160
GLY A 182
LYS A 185
ASP A 207
ASP A 209
HIS A 210
 None
None
None
CA  A 778 (-2.9A)
None
None
 0.55A 6ag0C-2dieA:
64.2		 6ag0C-2dieA:
32.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6AG0_C_ACRC606_0
(ALPHA-AMYLASE)		 2die AMYLASE
(Bacillus
sp.
(in:
Bacteria)) 		5 / 6 GLY A   7
THR A  40
GLN A  98
TYR A 100
TYR A 363
 None
 0.31A 6ag0C-2dieA:
64.2		 6ag0C-2dieA:
32.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6AG0_C_ACRC607_0
(ALPHA-AMYLASE)		 2die AMYLASE
(Bacillus
sp.
(in:
Bacteria)) 		5 / 6 GLY A 304
TRP A 347
GLY A 433
PRO A 434
GLY A 477
 None
 0.38A 6ag0C-2dieA:
64.2		 6ag0C-2dieA:
32.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6AG0_C_ACRC608_0
(ALPHA-AMYLASE)		 2die AMYLASE
(Bacillus
sp.
(in:
Bacteria)) 		10 / 12 TRP A  15
GLU A 194
TYR A 198
LEU A 201
MET A 202
ASP A 236
LYS A 239
HIS A 240
HIS A 332
ASP A 333
 None
 0.49A 6ag0C-2dieA:
64.2		 6ag0C-2dieA:
32.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6AG0_C_ACRC608_0
(ALPHA-AMYLASE)		 2die AMYLASE
(Bacillus
sp.
(in:
Bacteria)) 		7 / 12 TRP A  15
LEU A 201
MET A 202
ASP A 236
TYR A 295
HIS A 332
ASP A 333
 None
 1.01A 6ag0C-2dieA:
64.2		 6ag0C-2dieA:
32.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6AG0_C_ACRC608_1
(ALPHA-AMYLASE)		 2die AMYLASE
(Bacillus
sp.
(in:
Bacteria)) 		3 / 3 TYR A  58
ALA A 339
LEU A 340
 None
 0.61A 6ag0C-2dieA:
64.2		 6ag0C-2dieA:
32.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6AG0_C_ACRC609_0
(ALPHA-AMYLASE)		 2die AMYLASE
(Bacillus
sp.
(in:
Bacteria)) 		7 / 7 LYS A  72
GLY A 110
TRP A 140
ASP A 166
TRP A 167
MET A 202
TYR A 203
 None
 0.33A 6ag0C-2dieA:
64.2		 6ag0C-2dieA:
32.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBV_D_FI8D1904_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 2die AMYLASE
(Bacillus
sp.
(in:
Bacteria)) 		4 / 8 ARG A 234
VAL A 213
ARG A 148
GLN A  71
 None
 1.19A 6fbvD-2dieA:
undetectable		 6fbvD-2dieA:
15.96