SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2dj0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_C_CCSC47_0
(GLUTATHIONE
S-TRANSFERASE)		 2dj0 THIOREDOXIN-RELATED
TRANSMEMBRANE
PROTEIN 2
(Homo
sapiens) 		4 / 6 LEU A 128
GLY A 133
LYS A  54
TYR A  55
 None
 1.03A 1gtiC-2dj0A:
undetectable		 1gtiC-2dj0A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_D_CCSD47_0
(GLUTATHIONE
S-TRANSFERASE)		 2dj0 THIOREDOXIN-RELATED
TRANSMEMBRANE
PROTEIN 2
(Homo
sapiens) 		4 / 7 LEU A 128
GLY A 133
LYS A  54
TYR A  55
 None
 1.03A 1gtiD-2dj0A:
undetectable		 1gtiD-2dj0A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_E_CCSE47_0
(GLUTATHIONE
S-TRANSFERASE)		 2dj0 THIOREDOXIN-RELATED
TRANSMEMBRANE
PROTEIN 2
(Homo
sapiens) 		4 / 7 LEU A 128
GLY A 133
LYS A  54
TYR A  55
 None
 1.03A 1gtiE-2dj0A:
undetectable		 1gtiE-2dj0A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_F_CCSF47_0
(GLUTATHIONE
S-TRANSFERASE)		 2dj0 THIOREDOXIN-RELATED
TRANSMEMBRANE
PROTEIN 2
(Homo
sapiens) 		4 / 5 LEU A 128
GLY A 133
LYS A  54
TYR A  55
 None
 1.03A 1gtiF-2dj0A:
undetectable		 1gtiF-2dj0A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K37_B_BCZB468_1
(NEURAMINIDASE)		 2dj0 THIOREDOXIN-RELATED
TRANSMEMBRANE
PROTEIN 2
(Homo
sapiens) 		3 / 3 ARG A 124
GLU A 130
TYR A  55
 None
 0.94A 3k37B-2dj0A:
undetectable		 3k37B-2dj0A:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA504_1
(CYTOCHROME P450 2C9)		 2dj0 THIOREDOXIN-RELATED
TRANSMEMBRANE
PROTEIN 2
(Homo
sapiens) 		4 / 8 PHE A 126
ILE A  30
PRO A  46
PHE A  44
 None
 1.15A 5x23A-2dj0A:
undetectable		 5x23A-2dj0A:
14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_G_CHDG401_0
(BILE SALT HYDROLASE)		 2dj0 THIOREDOXIN-RELATED
TRANSMEMBRANE
PROTEIN 2
(Homo
sapiens) 		5 / 10 TYR A  48
ASN A  61
LEU A  91
LEU A  93
LEU A  60
 None
 1.25A 5y7pG-2dj0A:
undetectable		 5y7pG-2dj0A:
19.39