SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2djk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HJH_A_NCAA900_0
(NAD-DEPENDENT
HISTONE DEACETYLASE
SIR2)		 2djk PROTEIN
DISULFIDE-ISOMERASE
(Humicola
insolens) 		4 / 5 ILE A  84
PRO A  94
PHE A  95
ILE A  47
 None
 1.11A 2hjhA-2djkA:
undetectable		 2hjhA-2djkA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_A_NCTA501_1
(CYTOCHROME P450 2A6)		 2djk PROTEIN
DISULFIDE-ISOMERASE
(Humicola
insolens) 		4 / 7 PHE A  82
ASN A  56
GLY A  58
ILE A  47
 None
 0.89A 4ejjA-2djkA:
undetectable		 4ejjA-2djkA:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_B_X2NB590_2
(CYP51 VARIANT1)		 2djk PROTEIN
DISULFIDE-ISOMERASE
(Humicola
insolens) 		3 / 3 PRO A 120
LEU A  72
SER A 124
 None
 0.85A 5fsaB-2djkA:
undetectable		 5fsaB-2djkA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_A_TESA503_1
(-)		 2djk PROTEIN
DISULFIDE-ISOMERASE
(Humicola
insolens) 		5 / 9 LEU A  72
LEU A  74
ILE A  29
LEU A  26
ALA A  62
 None
 1.38A 5og9A-2djkA:
undetectable		 5og9A-2djkA:
13.77