SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2dkd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DRB_B_MTXB361_1
(DIHYDROFOLATE
REDUCTASE)		 2dkd PHOSPHOACETYLGLUCOSA
MINE MUTASE
(Candida
albicans) 		5 / 12 ILE A 339
PHE A 327
ILE A 404
LEU A 421
ILE A 382
 None
 0.87A 1drbB-2dkdA:
undetectable		 1drbB-2dkdA:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4002_1
(SERUM ALBUMIN)		 2dkd PHOSPHOACETYLGLUCOSA
MINE MUTASE
(Candida
albicans) 		4 / 5 ALA A  65
ALA A  33
LYS A  32
GLU A  71
 None
 1.17A 1e7cA-2dkdA:
2.3		 1e7cA-2dkdA:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4007_1
(SERUM ALBUMIN)		 2dkd PHOSPHOACETYLGLUCOSA
MINE MUTASE
(Candida
albicans) 		4 / 8 LEU A 199
PHE A 203
LEU A 236
LEU A 235
 None
 0.79A 1e7cA-2dkdA:
2.3		 1e7cA-2dkdA:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRQ_A_STRA501_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C1)		 2dkd PHOSPHOACETYLGLUCOSA
MINE MUTASE
(Candida
albicans) 		5 / 11 VAL A 248
ILE A 221
GLU A 174
LEU A 199
LEU A 440
 None
 1.17A 1mrqA-2dkdA:
undetectable		 1mrqA-2dkdA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RA2_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 2dkd PHOSPHOACETYLGLUCOSA
MINE MUTASE
(Candida
albicans) 		5 / 12 ILE A 339
PHE A 327
ILE A 404
LEU A 421
ILE A 382
 None
 0.92A 1ra2A-2dkdA:
undetectable		 1ra2A-2dkdA:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RA8_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 2dkd PHOSPHOACETYLGLUCOSA
MINE MUTASE
(Candida
albicans) 		5 / 12 ILE A 339
PHE A 327
ILE A 404
LEU A 421
ILE A 382
 None
 0.92A 1ra8A-2dkdA:
undetectable		 1ra8A-2dkdA:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RB2_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 2dkd PHOSPHOACETYLGLUCOSA
MINE MUTASE
(Candida
albicans) 		5 / 12 ILE A 339
PHE A 327
ILE A 404
LEU A 421
ILE A 382
 None
 0.88A 1rb2A-2dkdA:
undetectable		 1rb2A-2dkdA:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RD7_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 2dkd PHOSPHOACETYLGLUCOSA
MINE MUTASE
(Candida
albicans) 		5 / 12 ILE A 339
PHE A 327
ILE A 404
LEU A 421
ILE A 382
 None
 0.89A 1rd7A-2dkdA:
undetectable		 1rd7A-2dkdA:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RX2_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 2dkd PHOSPHOACETYLGLUCOSA
MINE MUTASE
(Candida
albicans) 		5 / 12 ILE A 339
PHE A 327
ILE A 404
LEU A 421
ILE A 382
 None
 0.95A 1rx2A-2dkdA:
undetectable		 1rx2A-2dkdA:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RX7_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 2dkd PHOSPHOACETYLGLUCOSA
MINE MUTASE
(Candida
albicans) 		5 / 12 ILE A 339
PHE A 327
ILE A 404
LEU A 421
ILE A 382
 None
 0.93A 1rx7A-2dkdA:
undetectable		 1rx7A-2dkdA:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_A_NFZA1219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 2dkd PHOSPHOACETYLGLUCOSA
MINE MUTASE
(Candida
albicans) 		4 / 8 TYR A  24
PHE A  22
GLY A  25
THR A 516
 None
None
None
NG1  A 901 (-3.0A)
 0.98A 1ykiA-2dkdA:
undetectable
1ykiB-2dkdA:
undetectable		 1ykiA-2dkdA:
19.12
1ykiB-2dkdA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1M_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 2dkd PHOSPHOACETYLGLUCOSA
MINE MUTASE
(Candida
albicans) 		4 / 7 THR A  64
VAL A 227
GLY A 226
ASP A 294
 None
None
None
ZN  A 921 ( 2.3A)
 0.80A 2a1mA-2dkdA:
undetectable		 2a1mA-2dkdA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1O_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 2dkd PHOSPHOACETYLGLUCOSA
MINE MUTASE
(Candida
albicans) 		4 / 8 THR A  64
VAL A 227
GLY A 226
ASP A 294
 None
None
None
ZN  A 921 ( 2.3A)
 0.84A 2a1oA-2dkdA:
undetectable		 2a1oA-2dkdA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CDQ_A_SAMA1500_0
(ASPARTOKINASE)		 2dkd PHOSPHOACETYLGLUCOSA
MINE MUTASE
(Candida
albicans) 		4 / 8 ILE A 244
SER A 245
ASP A 218
LEU A 443
 None
 1.00A 2cdqA-2dkdA:
undetectable		 2cdqA-2dkdA:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D0K_B_FOLB2161_0
(DIHYDROFOLATE
REDUCTASE)		 2dkd PHOSPHOACETYLGLUCOSA
MINE MUTASE
(Candida
albicans) 		5 / 12 ILE A 339
PHE A 327
ILE A 404
LEU A 421
ILE A 382
 None
 0.91A 2d0kB-2dkdA:
undetectable		 2d0kB-2dkdA:
16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTJ_B_THRB402_0
(ASPARTOKINASE)		 2dkd PHOSPHOACETYLGLUCOSA
MINE MUTASE
(Candida
albicans) 		5 / 9 ILE A  63
ASP A 140
GLY A 168
ALA A 138
THR A  64
 None
 1.38A 2dtjA-2dkdA:
undetectable
2dtjB-2dkdA:
undetectable		 2dtjA-2dkdA:
17.46
2dtjB-2dkdA:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J5M_A_ACTA1321_0
(CHLOROPEROXIDASE)		 2dkd PHOSPHOACETYLGLUCOSA
MINE MUTASE
(Candida
albicans) 		4 / 6 LEU A 359
ILE A 339
VAL A 341
ALA A 320
 None
 0.94A 2j5mA-2dkdA:
undetectable		 2j5mA-2dkdA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KOT_B_ANWB99_0
(PROTEIN S100-A13)		 2dkd PHOSPHOACETYLGLUCOSA
MINE MUTASE
(Candida
albicans) 		4 / 8 VAL A  20
THR A  21
PHE A  22
THR A  23
 None
 1.14A 2kotB-2dkdA:
undetectable		 2kotB-2dkdA:
9.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNK_A_ROCA401_3
(PROTEASE)		 2dkd PHOSPHOACETYLGLUCOSA
MINE MUTASE
(Candida
albicans) 		5 / 12 ILE A 153
GLY A 155
ILE A  45
VAL A  59
VAL A  61
 None
 0.89A 2nnkB-2dkdA:
undetectable		 2nnkB-2dkdA:
11.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OTH_A_NIMA300_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 2dkd PHOSPHOACETYLGLUCOSA
MINE MUTASE
(Candida
albicans) 		4 / 5 LEU A 315
ALA A 441
ILE A 428
SER A 437
 None
 0.97A 2othA-2dkdA:
undetectable		 2othA-2dkdA:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2dkd PHOSPHOACETYLGLUCOSA
MINE MUTASE
(Candida
albicans) 		4 / 8 LEU A 175
LEU A  85
VAL A  43
GLY A  44
 None
 0.93A 2po5B-2dkdA:
undetectable		 2po5B-2dkdA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBL_A_CAMA517_0
(CYTOCHROME P450-CAM)		 2dkd PHOSPHOACETYLGLUCOSA
MINE MUTASE
(Candida
albicans) 		4 / 7 LEU A 175
VAL A 178
THR A 179
ASP A 166
 None
 0.98A 2qblA-2dkdA:
undetectable		 2qblA-2dkdA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_F_ASDF1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 2dkd PHOSPHOACETYLGLUCOSA
MINE MUTASE
(Candida
albicans) 		5 / 8 LEU A 199
LEU A 235
ALA A 441
LEU A 439
PHE A 289
 None
 1.46A 2vcvF-2dkdA:
undetectable		 2vcvF-2dkdA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XCT_H_CPFH1020_1
(DNA GYRASE SUBUNIT
B, DNA GYRASE
SUBUNIT A)		 2dkd PHOSPHOACETYLGLUCOSA
MINE MUTASE
(Candida
albicans) 		3 / 3 ARG A 512
GLU A 484
SER A 351
 NG1  A 901 (-3.0A)
None
None
 0.84A 2xctD-2dkdA:
undetectable		 2xctD-2dkdA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_B_SAMB530_1
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)		 2dkd PHOSPHOACETYLGLUCOSA
MINE MUTASE
(Candida
albicans) 		3 / 3 TYR A 346
GLU A 484
THR A  26
 NG1  A 901 ( 3.6A)
None
NG1  A 901 (-4.8A)
 1.03A 2y7hB-2dkdA:
undetectable		 2y7hB-2dkdA:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_A_SAMA801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 2dkd PHOSPHOACETYLGLUCOSA
MINE MUTASE
(Candida
albicans) 		4 / 8 THR A 344
ARG A 508
ASP A 266
GLU A 525
 None
 0.97A 2zw9A-2dkdA:
undetectable		 2zw9A-2dkdA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_A_SAMA801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 2dkd PHOSPHOACETYLGLUCOSA
MINE MUTASE
(Candida
albicans) 		4 / 8 THR A 344
ARG A 508
ASP A 311
GLU A 525
 None
 1.07A 2zw9A-2dkdA:
undetectable		 2zw9A-2dkdA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APW_B_DP0B190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 2dkd PHOSPHOACETYLGLUCOSA
MINE MUTASE
(Candida
albicans) 		5 / 12 VAL A 355
ILE A 361
LEU A 449
GLN A 324
SER A 316
 None
 1.16A 3apwB-2dkdA:
undetectable		 3apwB-2dkdA:
16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_A_CHDA3_0
(FERROCHELATASE)		 2dkd PHOSPHOACETYLGLUCOSA
MINE MUTASE
(Candida
albicans) 		3 / 3 PRO A 490
LEU A 487
ARG A 512
 None
None
NG1  A 901 (-3.0A)
 0.88A 3aqiA-2dkdA:
undetectable		 3aqiA-2dkdA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_A_ECLA600_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2dkd PHOSPHOACETYLGLUCOSA
MINE MUTASE
(Candida
albicans) 		4 / 8 LEU A 318
THR A 317
TYR A 460
ALA A 388
 None
 0.81A 3jusA-2dkdA:
undetectable		 3jusA-2dkdA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_A_ECNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2dkd PHOSPHOACETYLGLUCOSA
MINE MUTASE
(Candida
albicans) 		4 / 8 LEU A 318
THR A 317
TYR A 460
ALA A 388
 None
 0.81A 3jusA-2dkdA:
undetectable		 3jusA-2dkdA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_B_ECLB600_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2dkd PHOSPHOACETYLGLUCOSA
MINE MUTASE
(Candida
albicans) 		4 / 8 LEU A 318
THR A 317
TYR A 460
ALA A 388
 None
 0.78A 3jusB-2dkdA:
undetectable		 3jusB-2dkdA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K9F_F_LFXF0_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B)		 2dkd PHOSPHOACETYLGLUCOSA
MINE MUTASE
(Candida
albicans) 		4 / 5 SER A  66
ARG A 295
GLY A 369
GLU A 484
 ZN  A 921 ( 2.3A)
PO4  A 911 ( 4.1A)
NG1  A 901 ( 3.7A)
None
 1.30A 3k9fA-2dkdA:
2.4
3k9fB-2dkdA:
2.4
3k9fC-2dkdA:
undetectable		 3k9fA-2dkdA:
22.28
3k9fB-2dkdA:
22.28
3k9fC-2dkdA:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MB5_A_SAMA301_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 2dkd PHOSPHOACETYLGLUCOSA
MINE MUTASE
(Candida
albicans) 		5 / 12 ILE A 471
VAL A 472
ALA A 519
ILE A 497
LEU A 542
 None
 0.90A 3mb5A-2dkdA:
undetectable		 3mb5A-2dkdA:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZV_B_ECNB411_1
(FLAVOHEMOGLOBIN)		 2dkd PHOSPHOACETYLGLUCOSA
MINE MUTASE
(Candida
albicans) 		5 / 9 ILE A 219
ILE A 221
ALA A 435
LEU A 439
LEU A 285
 None
 1.06A 3ozvB-2dkdA:
undetectable		 3ozvB-2dkdA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEL_D_QELD2_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
EPSILON-2)		 2dkd PHOSPHOACETYLGLUCOSA
MINE MUTASE
(Candida
albicans) 		4 / 5 TYR A  24
THR A  23
PHE A  22
LEU A  96
 None
 1.06A 3qelC-2dkdA:
undetectable		 3qelC-2dkdA:
23.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RET_A_SALA201_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)		 2dkd PHOSPHOACETYLGLUCOSA
MINE MUTASE
(Candida
albicans) 		5 / 10 ALA A 441
VAL A 445
TYR A 207
ILE A 206
ILE A 217
 None
 1.38A 3retA-2dkdA:
undetectable
3retB-2dkdA:
undetectable		 3retA-2dkdA:
12.87
3retB-2dkdA:
12.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJ1_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 2dkd PHOSPHOACETYLGLUCOSA
MINE MUTASE
(Candida
albicans) 		5 / 12 ILE A 339
PHE A 327
ILE A 404
LEU A 421
ILE A 382
 None
 0.90A 4ej1A-2dkdA:
undetectable		 4ej1A-2dkdA:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FHB_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 2dkd PHOSPHOACETYLGLUCOSA
MINE MUTASE
(Candida
albicans) 		5 / 12 ILE A 339
PHE A 327
ILE A 404
LEU A 421
ILE A 382
 None
 0.89A 4fhbA-2dkdA:
undetectable		 4fhbA-2dkdA:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HFP_D_15UD402_1
(PROTHROMBIN)		 2dkd PHOSPHOACETYLGLUCOSA
MINE MUTASE
(Candida
albicans) 		5 / 12 HIS A 176
LEU A 175
ILE A 137
ALA A  27
GLY A  74
 None
 1.06A 4hfpD-2dkdA:
undetectable		 4hfpD-2dkdA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I13_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 2dkd PHOSPHOACETYLGLUCOSA
MINE MUTASE
(Candida
albicans) 		5 / 12 ILE A 339
PHE A 327
ILE A 404
LEU A 421
ILE A 382
 None
 0.92A 4i13A-2dkdA:
undetectable		 4i13A-2dkdA:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JX1_F_CAMF502_0
(CAMPHOR
5-MONOOXYGENASE)		 2dkd PHOSPHOACETYLGLUCOSA
MINE MUTASE
(Candida
albicans) 		4 / 4 TYR A 195
THR A 172
VAL A 432
ILE A 436
 None
 1.30A 4jx1F-2dkdA:
undetectable		 4jx1F-2dkdA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KJJ_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 2dkd PHOSPHOACETYLGLUCOSA
MINE MUTASE
(Candida
albicans) 		5 / 12 ILE A 339
PHE A 327
ILE A 404
LEU A 421
ILE A 382
 None
 0.98A 4kjjA-2dkdA:
undetectable		 4kjjA-2dkdA:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KJK_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 2dkd PHOSPHOACETYLGLUCOSA
MINE MUTASE
(Candida
albicans) 		5 / 12 ILE A 339
PHE A 327
ILE A 404
LEU A 421
ILE A 382
 None
 0.92A 4kjkA-2dkdA:
undetectable		 4kjkA-2dkdA:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KJL_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 2dkd PHOSPHOACETYLGLUCOSA
MINE MUTASE
(Candida
albicans) 		5 / 12 ILE A 339
PHE A 327
ILE A 404
LEU A 421
ILE A 382
 None
 0.94A 4kjlA-2dkdA:
undetectable		 4kjlA-2dkdA:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1X_B_STRB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 2dkd PHOSPHOACETYLGLUCOSA
MINE MUTASE
(Candida
albicans) 		5 / 9 VAL A 248
ILE A 221
GLU A 174
LEU A 199
LEU A 440
 None
 1.11A 4l1xB-2dkdA:
0.0		 4l1xB-2dkdA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NTX_A_AMRA509_1
(ACID-SENSING ION
CHANNEL 1
BASIC PHOSPHOLIPASE
A2 HOMOLOG TX-BETA)		 2dkd PHOSPHOACETYLGLUCOSA
MINE MUTASE
(Candida
albicans) 		4 / 6 ASP A 294
ASP A 292
ASN A  68
ARG A  30
 ZN  A 921 ( 2.3A)
ZN  A 921 ( 2.4A)
None
PO4  A 911 ( 3.9A)
 1.13A 4ntxA-2dkdA:
undetectable
4ntxC-2dkdA:
0.3		 4ntxA-2dkdA:
22.07
4ntxC-2dkdA:
11.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P3Q_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 2dkd PHOSPHOACETYLGLUCOSA
MINE MUTASE
(Candida
albicans) 		5 / 12 ILE A 339
PHE A 327
ILE A 404
LEU A 421
ILE A 382
 None
 0.99A 4p3qA-2dkdA:
undetectable		 4p3qA-2dkdA:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P3R_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 2dkd PHOSPHOACETYLGLUCOSA
MINE MUTASE
(Candida
albicans) 		5 / 12 ILE A 339
PHE A 327
ILE A 404
LEU A 421
ILE A 382
 None
 0.95A 4p3rA-2dkdA:
undetectable		 4p3rA-2dkdA:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PSS_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 2dkd PHOSPHOACETYLGLUCOSA
MINE MUTASE
(Candida
albicans) 		5 / 12 ILE A 339
PHE A 327
ILE A 404
LEU A 421
ILE A 382
 None
 0.95A 4pssA-2dkdA:
undetectable		 4pssA-2dkdA:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U15_A_0HKA2001_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 2dkd PHOSPHOACETYLGLUCOSA
MINE MUTASE
(Candida
albicans) 		3 / 3 ASN A 302
PHE A 307
TYR A 286
 None
 0.77A 4u15A-2dkdA:
undetectable		 4u15A-2dkdA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNV_A_QI9A602_0
(CYTOCHROME P450 2D6)		 2dkd PHOSPHOACETYLGLUCOSA
MINE MUTASE
(Candida
albicans) 		5 / 9 PHE A 156
SER A 149
VAL A 135
PHE A 167
LEU A 175
 None
 1.39A 4wnvA-2dkdA:
0.0		 4wnvA-2dkdA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5I_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 2dkd PHOSPHOACETYLGLUCOSA
MINE MUTASE
(Candida
albicans) 		5 / 12 ILE A 339
PHE A 327
ILE A 404
LEU A 421
ILE A 382
 None
 0.88A 4x5iA-2dkdA:
undetectable		 4x5iA-2dkdA:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XTA_B_DIFB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2dkd PHOSPHOACETYLGLUCOSA
MINE MUTASE
(Candida
albicans) 		4 / 8 SER A 245
LEU A 443
LEU A 440
ILE A 232
 None
 0.91A 4xtaB-2dkdA:
undetectable		 4xtaB-2dkdA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EAJ_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 2dkd PHOSPHOACETYLGLUCOSA
MINE MUTASE
(Candida
albicans) 		5 / 12 ILE A 339
PHE A 327
ILE A 404
LEU A 421
ILE A 382
 None
 0.92A 5eajA-2dkdA:
undetectable		 5eajA-2dkdA:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOC_B_SAMB401_0
(PAVINE
N-METHYLTRANSFERASE)		 2dkd PHOSPHOACETYLGLUCOSA
MINE MUTASE
(Candida
albicans) 		5 / 12 GLY A 392
GLY A 433
SER A 437
VAL A 394
HIS A 374
 None
 1.10A 5kocB-2dkdA:
undetectable		 5kocB-2dkdA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_B_OAQB302_0
(SULFOTRANSFERASE)		 2dkd PHOSPHOACETYLGLUCOSA
MINE MUTASE
(Candida
albicans) 		5 / 12 ILE A 436
VAL A 248
ILE A 219
PHE A 289
LEU A 240
 None
 1.17A 5tiwB-2dkdA:
undetectable		 5tiwB-2dkdA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TOA_A_ESTA601_1
(ESTROGEN RECEPTOR
BETA)		 2dkd PHOSPHOACETYLGLUCOSA
MINE MUTASE
(Candida
albicans) 		5 / 12 LEU A  49
ALA A  47
LEU A  96
ILE A   3
LEU A 114
 None
 0.96A 5toaA-2dkdA:
undetectable		 5toaA-2dkdA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UJX_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 2dkd PHOSPHOACETYLGLUCOSA
MINE MUTASE
(Candida
albicans) 		5 / 12 ILE A 339
PHE A 327
ILE A 404
LEU A 421
ILE A 382
 None
 0.91A 5ujxA-2dkdA:
undetectable		 5ujxA-2dkdA:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WGG_A_SAMA504_0
(RADICAL SAM DOMAIN
PROTEIN)		 2dkd PHOSPHOACETYLGLUCOSA
MINE MUTASE
(Candida
albicans) 		5 / 12 TYR A 385
PHE A 424
ASN A 429
VAL A 342
VAL A 341
 None
 1.22A 5wggA-2dkdA:
1.6		 5wggA-2dkdA:
24.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z6J_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 2dkd PHOSPHOACETYLGLUCOSA
MINE MUTASE
(Candida
albicans) 		5 / 12 ILE A 339
PHE A 327
ILE A 404
LEU A 421
ILE A 382
 None
 0.95A 5z6jA-2dkdA:
undetectable		 5z6jA-2dkdA:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z6K_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 2dkd PHOSPHOACETYLGLUCOSA
MINE MUTASE
(Candida
albicans) 		5 / 12 ILE A 339
PHE A 327
ILE A 404
LEU A 421
ILE A 382
 None
 0.96A 5z6kA-2dkdA:
undetectable		 5z6kA-2dkdA:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AZ3_1_PAR11803_1
(RRNA ALPHA
RIBOSOMAL PROTEIN
EL18)		 2dkd PHOSPHOACETYLGLUCOSA
MINE MUTASE
(Candida
albicans) 		3 / 3 SER A 536
LYS A 537
SER A 540
 None
 0.64A 6az3P-2dkdA:
undetectable		 6az3P-2dkdA:
11.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
7DFR_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 2dkd PHOSPHOACETYLGLUCOSA
MINE MUTASE
(Candida
albicans) 		5 / 12 ILE A 339
PHE A 327
ILE A 404
LEU A 421
ILE A 382
 None
 0.96A 7dfrA-2dkdA:
undetectable		 7dfrA-2dkdA:
15.26