SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2dkj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1DFO_A_FFOA1002_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	2dkj	SERINE HYDROXYMETHYLTRANSFE RASE (Thermus thermophilus)	8 / 12	LEU A 117 GLY A 120 HIS A 122 LEU A 123 VAL A 129 SER A 172 ALA A 173 ARG A 358	None None PLP A 510 (-3.5A) None None PLP A 510 ( 3.2A) None SO4 A2520 (-2.9A)	0.46A	1dfoA-2dkjA: 60.5	1dfoA-2dkjA: 59.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1DFO_A_FFOA1002_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	2dkj	SERINE HYDROXYMETHYLTRANSFE RASE (Thermus thermophilus)	7 / 12	LEU A 117 GLY A 120 HIS A 122 SER A 172 ALA A 173 ASN A 342 ARG A 358	None None PLP A 510 (-3.5A) PLP A 510 ( 3.2A) None None SO4 A2520 (-2.9A)	0.83A	1dfoA-2dkjA: 60.5	1dfoA-2dkjA: 59.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1DFO_A_FFOA1002_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	2dkj	SERINE HYDROXYMETHYLTRANSFE RASE (Thermus thermophilus)	5 / 5	GLU A 53 TYR A 60 TYR A 61 PHE A 252 PRO A 253	None	0.33A	1dfoB-2dkjA: 61.9	1dfoB-2dkjA: 59.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1DFO_B_FFOB2002_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	2dkj	SERINE HYDROXYMETHYLTRANSFE RASE (Thermus thermophilus)	5 / 5	GLU A 53 TYR A 60 TYR A 61 PHE A 252 PRO A 253	None	0.33A	1dfoA-2dkjA: 60.5	1dfoA-2dkjA: 59.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1DFO_B_FFOB2002_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	2dkj	SERINE HYDROXYMETHYLTRANSFE RASE (Thermus thermophilus)	8 / 12	LEU A 117 GLY A 120 HIS A 122 LEU A 123 VAL A 129 SER A 172 ALA A 173 ARG A 358	None None PLP A 510 (-3.5A) None None PLP A 510 ( 3.2A) None SO4 A2520 (-2.9A)	0.47A	1dfoB-2dkjA: 61.9	1dfoB-2dkjA: 59.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1DFO_B_FFOB2002_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	2dkj	SERINE HYDROXYMETHYLTRANSFE RASE (Thermus thermophilus)	7 / 12	LEU A 117 GLY A 120 HIS A 122 SER A 172 ALA A 173 ASN A 342 ARG A 358	None None PLP A 510 (-3.5A) PLP A 510 ( 3.2A) None None SO4 A2520 (-2.9A)	0.84A	1dfoB-2dkjA: 61.9	1dfoB-2dkjA: 59.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1DFO_C_FFOC3002_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	2dkj	SERINE HYDROXYMETHYLTRANSFE RASE (Thermus thermophilus)	8 / 12	LEU A 117 GLY A 120 HIS A 122 LEU A 123 VAL A 129 SER A 172 ALA A 173 ARG A 358	None None PLP A 510 (-3.5A) None None PLP A 510 ( 3.2A) None SO4 A2520 (-2.9A)	0.46A	1dfoC-2dkjA: 61.9	1dfoC-2dkjA: 59.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1DFO_C_FFOC3002_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	2dkj	SERINE HYDROXYMETHYLTRANSFE RASE (Thermus thermophilus)	7 / 12	LEU A 117 GLY A 120 HIS A 122 SER A 172 ALA A 173 ASN A 342 ARG A 358	None None PLP A 510 (-3.5A) PLP A 510 ( 3.2A) None None SO4 A2520 (-2.9A)	0.83A	1dfoC-2dkjA: 61.9	1dfoC-2dkjA: 59.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1DFO_C_FFOC3002_2 (SERINE HYDROXYMETHYLTRANSFE RASE)	2dkj	SERINE HYDROXYMETHYLTRANSFE RASE (Thermus thermophilus)	5 / 5	GLU A 53 TYR A 60 TYR A 61 PHE A 252 PRO A 253	None	0.33A	1dfoD-2dkjA: 60.5	1dfoD-2dkjA: 59.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1DFO_D_FFOD4002_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	2dkj	SERINE HYDROXYMETHYLTRANSFE RASE (Thermus thermophilus)	5 / 5	GLU A 53 TYR A 60 TYR A 61 PHE A 252 PRO A 253	None	0.33A	1dfoC-2dkjA: 61.9	1dfoC-2dkjA: 59.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1DFO_D_FFOD4002_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	2dkj	SERINE HYDROXYMETHYLTRANSFE RASE (Thermus thermophilus)	8 / 12	LEU A 117 GLY A 120 HIS A 122 LEU A 123 VAL A 129 SER A 172 ALA A 173 ARG A 358	None None PLP A 510 (-3.5A) None None PLP A 510 ( 3.2A) None SO4 A2520 (-2.9A)	0.47A	1dfoD-2dkjA: 60.5	1dfoD-2dkjA: 59.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1DFO_D_FFOD4002_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	2dkj	SERINE HYDROXYMETHYLTRANSFE RASE (Thermus thermophilus)	7 / 12	LEU A 117 GLY A 120 HIS A 122 SER A 172 ALA A 173 ASN A 342 ARG A 358	None None PLP A 510 (-3.5A) PLP A 510 ( 3.2A) None None SO4 A2520 (-2.9A)	0.84A	1dfoD-2dkjA: 60.5	1dfoD-2dkjA: 59.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1EQB_A_FFOA1293_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	2dkj	SERINE HYDROXYMETHYLTRANSFE RASE (Thermus thermophilus)	8 / 12	LEU A 117 GLY A 120 HIS A 122 LEU A 123 VAL A 129 SER A 172 ALA A 173 ARG A 358	None None PLP A 510 (-3.5A) None None PLP A 510 ( 3.2A) None SO4 A2520 (-2.9A)	0.45A	1eqbA-2dkjA: 60.3	1eqbA-2dkjA: 59.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1EQB_A_FFOA1293_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	2dkj	SERINE HYDROXYMETHYLTRANSFE RASE (Thermus thermophilus)	6 / 12	LEU A 117 GLY A 120 SER A 172 ALA A 173 ASN A 342 ARG A 358	None None PLP A 510 ( 3.2A) None None SO4 A2520 (-2.9A)	0.83A	1eqbA-2dkjA: 60.3	1eqbA-2dkjA: 59.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1EQB_A_FFOA1293_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	2dkj	SERINE HYDROXYMETHYLTRANSFE RASE (Thermus thermophilus)	3 / 3	GLU A 53 TYR A 60 PHE A 252	None	0.39A	1eqbB-2dkjA: 61.9	1eqbB-2dkjA: 59.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1EQB_A_GLYA1292_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	2dkj	SERINE HYDROXYMETHYLTRANSFE RASE (Thermus thermophilus)	6 / 8	SER A 31 HIS A 122 SER A 172 HIS A 200 LYS A 226 ARG A 358	SO4 A2520 (-2.7A) PLP A 510 (-3.5A) PLP A 510 ( 3.2A) SO4 A2520 ( 4.0A) PLP A 510 ( 1.3A) SO4 A2520 (-2.9A)	0.49A	1eqbA-2dkjA: 60.3 1eqbB-2dkjA: 61.9	1eqbA-2dkjA: 59.52 1eqbB-2dkjA: 59.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1EQB_B_FFOB2293_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	2dkj	SERINE HYDROXYMETHYLTRANSFE RASE (Thermus thermophilus)	3 / 3	GLU A 53 TYR A 60 PHE A 252	None	0.38A	1eqbA-2dkjA: 60.3	1eqbA-2dkjA: 59.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1EQB_B_FFOB2293_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	2dkj	SERINE HYDROXYMETHYLTRANSFE RASE (Thermus thermophilus)	8 / 12	LEU A 117 GLY A 120 HIS A 122 LEU A 123 VAL A 129 SER A 172 ALA A 173 ARG A 358	None None PLP A 510 (-3.5A) None None PLP A 510 ( 3.2A) None SO4 A2520 (-2.9A)	0.45A	1eqbB-2dkjA: 61.9	1eqbB-2dkjA: 59.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1EQB_B_FFOB2293_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	2dkj	SERINE HYDROXYMETHYLTRANSFE RASE (Thermus thermophilus)	6 / 12	LEU A 117 GLY A 120 SER A 172 ALA A 173 ASN A 342 ARG A 358	None None PLP A 510 ( 3.2A) None None SO4 A2520 (-2.9A)	0.82A	1eqbB-2dkjA: 61.9	1eqbB-2dkjA: 59.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1EQB_B_GLYB2292_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	2dkj	SERINE HYDROXYMETHYLTRANSFE RASE (Thermus thermophilus)	6 / 8	SER A 31 HIS A 122 SER A 172 HIS A 200 LYS A 226 ARG A 358	SO4 A2520 (-2.7A) PLP A 510 (-3.5A) PLP A 510 ( 3.2A) SO4 A2520 ( 4.0A) PLP A 510 ( 1.3A) SO4 A2520 (-2.9A)	0.49A	1eqbA-2dkjA: 60.3 1eqbB-2dkjA: 61.9	1eqbA-2dkjA: 59.52 1eqbB-2dkjA: 59.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1EQB_C_FFOC3293_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	2dkj	SERINE HYDROXYMETHYLTRANSFE RASE (Thermus thermophilus)	8 / 12	LEU A 117 GLY A 120 HIS A 122 LEU A 123 VAL A 129 SER A 172 ALA A 173 ARG A 358	None None PLP A 510 (-3.5A) None None PLP A 510 ( 3.2A) None SO4 A2520 (-2.9A)	0.45A	1eqbC-2dkjA: 61.8	1eqbC-2dkjA: 59.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1EQB_C_FFOC3293_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	2dkj	SERINE HYDROXYMETHYLTRANSFE RASE (Thermus thermophilus)	6 / 12	LEU A 117 GLY A 120 SER A 172 ALA A 173 ASN A 342 ARG A 358	None None PLP A 510 ( 3.2A) None None SO4 A2520 (-2.9A)	0.83A	1eqbC-2dkjA: 61.8	1eqbC-2dkjA: 59.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1EQB_C_FFOC3293_2 (SERINE HYDROXYMETHYLTRANSFE RASE)	2dkj	SERINE HYDROXYMETHYLTRANSFE RASE (Thermus thermophilus)	3 / 3	GLU A 53 TYR A 60 PHE A 252	None	0.38A	1eqbD-2dkjA: 60.6	1eqbD-2dkjA: 59.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1EQB_C_GLYC3292_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	2dkj	SERINE HYDROXYMETHYLTRANSFE RASE (Thermus thermophilus)	6 / 8	SER A 31 HIS A 122 SER A 172 HIS A 200 LYS A 226 ARG A 358	SO4 A2520 (-2.7A) PLP A 510 (-3.5A) PLP A 510 ( 3.2A) SO4 A2520 ( 4.0A) PLP A 510 ( 1.3A) SO4 A2520 (-2.9A)	0.49A	1eqbC-2dkjA: 61.8 1eqbD-2dkjA: 60.6	1eqbC-2dkjA: 59.52 1eqbD-2dkjA: 59.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1EQB_D_FFOD4293_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	2dkj	SERINE HYDROXYMETHYLTRANSFE RASE (Thermus thermophilus)	3 / 3	GLU A 53 TYR A 60 PHE A 252	None	0.38A	1eqbC-2dkjA: 61.8	1eqbC-2dkjA: 59.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1EQB_D_FFOD4293_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	2dkj	SERINE HYDROXYMETHYLTRANSFE RASE (Thermus thermophilus)	8 / 12	LEU A 117 GLY A 120 HIS A 122 LEU A 123 VAL A 129 SER A 172 ALA A 173 ARG A 358	None None PLP A 510 (-3.5A) None None PLP A 510 ( 3.2A) None SO4 A2520 (-2.9A)	0.45A	1eqbD-2dkjA: 60.6	1eqbD-2dkjA: 59.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1EQB_D_FFOD4293_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	2dkj	SERINE HYDROXYMETHYLTRANSFE RASE (Thermus thermophilus)	6 / 12	LEU A 117 GLY A 120 SER A 172 ALA A 173 ASN A 342 ARG A 358	None None PLP A 510 ( 3.2A) None None SO4 A2520 (-2.9A)	0.83A	1eqbD-2dkjA: 60.6	1eqbD-2dkjA: 59.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1EQB_D_GLYD4292_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	2dkj	SERINE HYDROXYMETHYLTRANSFE RASE (Thermus thermophilus)	6 / 8	SER A 31 HIS A 122 SER A 172 HIS A 200 LYS A 226 ARG A 358	SO4 A2520 (-2.7A) PLP A 510 (-3.5A) PLP A 510 ( 3.2A) SO4 A2520 ( 4.0A) PLP A 510 ( 1.3A) SO4 A2520 (-2.9A)	0.50A	1eqbC-2dkjA: 61.8 1eqbD-2dkjA: 60.6	1eqbC-2dkjA: 59.52 1eqbD-2dkjA: 59.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GEB_A_CAMA418_0 (CYTOCHROME P450-CAM)	2dkj	SERINE HYDROXYMETHYLTRANSFE RASE (Thermus thermophilus)	5 / 9	PHE A 314 VAL A 377 ILE A 337 VAL A 339 ILE A 359	None	1.29A	1gebA-2dkjA: undetectable	1gebA-2dkjA: 22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1YA4_B_CTXB2_2 (CES1 PROTEIN)	2dkj	SERINE HYDROXYMETHYLTRANSFE RASE (Thermus thermophilus)	4 / 4	LEU A 400 PRO A 407 ILE A 364 LEU A 26	None	1.13A	1ya4B-2dkjA: undetectable	1ya4B-2dkjA: 22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2AVV_E_MK1E902_4 (POL POLYPROTEIN)	2dkj	SERINE HYDROXYMETHYLTRANSFE RASE (Thermus thermophilus)	3 / 3	ARG A 394 VAL A 377 GLY A 360	None	0.61A	2avvE-2dkjA: undetectable	2avvE-2dkjA: 13.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2PGF_A_ADNA501_1 (ADENOSINE DEAMINASE)	2dkj	SERINE HYDROXYMETHYLTRANSFE RASE (Thermus thermophilus)	5 / 12	PHE A 131 GLY A 126 HIS A 125 HIS A 122 SER A 95	None None PLP A 510 ( 4.7A) PLP A 510 (-3.5A) PLP A 510 (-2.7A)	1.34A	2pgfA-2dkjA: undetectable	2pgfA-2dkjA: 23.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2VMY_A_FFOA505_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	2dkj	SERINE HYDROXYMETHYLTRANSFE RASE (Thermus thermophilus)	5 / 6	GLU A 53 TYR A 60 TYR A 61 PHE A 252 PRO A 253	None	0.24A	2vmyA-2dkjA: 61.7	2vmyA-2dkjA: 66.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2VMY_A_FFOA505_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	2dkj	SERINE HYDROXYMETHYLTRANSFE RASE (Thermus thermophilus)	8 / 12	LEU A 117 GLY A 120 HIS A 122 LEU A 123 VAL A 129 SER A 172 ALA A 173 ARG A 358	None None PLP A 510 (-3.5A) None None PLP A 510 ( 3.2A) None SO4 A2520 (-2.9A)	0.47A	2vmyB-2dkjA: 60.4	2vmyB-2dkjA: 66.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2VMY_A_GLYA502_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	2dkj	SERINE HYDROXYMETHYLTRANSFE RASE (Thermus thermophilus)	5 / 7	SER A 31 HIS A 122 HIS A 200 LYS A 226 ARG A 358	SO4 A2520 (-2.7A) PLP A 510 (-3.5A) SO4 A2520 ( 4.0A) PLP A 510 ( 1.3A) SO4 A2520 (-2.9A)	0.50A	2vmyA-2dkjA: 61.7 2vmyB-2dkjA: 60.4	2vmyA-2dkjA: 66.01 2vmyB-2dkjA: 66.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2VMY_B_FFOB505_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	2dkj	SERINE HYDROXYMETHYLTRANSFE RASE (Thermus thermophilus)	5 / 12	HIS A 122 LEU A 123 VAL A 129 SER A 172 ASN A 342	PLP A 510 (-3.5A) None None PLP A 510 ( 3.2A) None	0.96A	2vmyA-2dkjA: 61.7	2vmyA-2dkjA: 66.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2VMY_B_FFOB505_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	2dkj	SERINE HYDROXYMETHYLTRANSFE RASE (Thermus thermophilus)	9 / 12	LEU A 117 GLY A 120 HIS A 122 LEU A 123 VAL A 129 SER A 172 ALA A 173 ASN A 340 ARG A 358	None None PLP A 510 (-3.5A) None None PLP A 510 ( 3.2A) None None SO4 A2520 (-2.9A)	0.57A	2vmyA-2dkjA: 61.7	2vmyA-2dkjA: 66.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2VMY_B_FFOB505_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	2dkj	SERINE HYDROXYMETHYLTRANSFE RASE (Thermus thermophilus)	4 / 4	GLU A 53 TYR A 60 TYR A 61 PHE A 252	None	0.33A	2vmyB-2dkjA: 60.4	2vmyB-2dkjA: 66.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2VMY_B_GLYB502_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	2dkj	SERINE HYDROXYMETHYLTRANSFE RASE (Thermus thermophilus)	6 / 8	SER A 31 HIS A 122 SER A 172 HIS A 200 LYS A 226 ARG A 358	SO4 A2520 (-2.7A) PLP A 510 (-3.5A) PLP A 510 ( 3.2A) SO4 A2520 ( 4.0A) PLP A 510 ( 1.3A) SO4 A2520 (-2.9A)	0.49A	2vmyA-2dkjA: 61.7 2vmyB-2dkjA: 60.4	2vmyA-2dkjA: 66.01 2vmyB-2dkjA: 66.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XF3_B_J01B500_1 (ORF12)	2dkj	SERINE HYDROXYMETHYLTRANSFE RASE (Thermus thermophilus)	5 / 9	VAL A 305 ILE A 344 LEU A 385 GLY A 325 ALA A 328	None	1.34A	2xf3B-2dkjA: 0.3	2xf3B-2dkjA: 24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XFS_B_J01B500_1 (ORF12)	2dkj	SERINE HYDROXYMETHYLTRANSFE RASE (Thermus thermophilus)	5 / 9	VAL A 305 ILE A 344 LEU A 385 GLY A 325 ALA A 328	None	1.32A	2xfsB-2dkjA: 0.0	2xfsB-2dkjA: 24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XH9_B_J01B1436_1 (ORF12)	2dkj	SERINE HYDROXYMETHYLTRANSFE RASE (Thermus thermophilus)	5 / 9	VAL A 305 ILE A 344 LEU A 385 GLY A 325 ALA A 328	None	1.35A	2xh9B-2dkjA: 0.3	2xh9B-2dkjA: 24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3A2Q_A_ACAA602_1 (6-AMINOHEXANOATE-CYC LIC-DIMER HYDROLASE)	2dkj	SERINE HYDROXYMETHYLTRANSFE RASE (Thermus thermophilus)	4 / 7	ASN A 88 ALA A 74 ALA A 78 GLN A 90	None	0.69A	3a2qA-2dkjA: undetectable	3a2qA-2dkjA: 26.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3EM4_V_DR7V100_2 (PROTEASE)	2dkj	SERINE HYDROXYMETHYLTRANSFE RASE (Thermus thermophilus)	5 / 10	ASP A 197 GLY A 233 GLY A 234 LEU A 235 VAL A 101	PLP A 510 (-2.8A) None None None None	1.08A	3em4V-2dkjA: undetectable	3em4V-2dkjA: 14.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KP6_A_SALA3002_1 (TRANSCRIPTIONAL REGULATOR TCAR)	2dkj	SERINE HYDROXYMETHYLTRANSFE RASE (Thermus thermophilus)	5 / 8	VAL A 101 LEU A 105 ILE A 236 VAL A 219 LEU A 243	None	1.14A	3kp6A-2dkjA: undetectable 3kp6B-2dkjA: undetectable	3kp6A-2dkjA: 16.38 3kp6B-2dkjA: 16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LB3_A_4CHA191_0 (DEHALOPEROXIDASE A)	2dkj	SERINE HYDROXYMETHYLTRANSFE RASE (Thermus thermophilus)	4 / 6	PHE A 183 TYR A 141 HIS A 125 VAL A 196	None None PLP A 510 ( 4.7A) None	1.18A	3lb3A-2dkjA: undetectable	3lb3A-2dkjA: 16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NXU_B_RITB600_1 (CYTOCHROME P450 3A4)	2dkj	SERINE HYDROXYMETHYLTRANSFE RASE (Thermus thermophilus)	5 / 12	PHE A 314 MET A 374 THR A 306 ILE A 364 ALA A 363	None	1.08A	3nxuB-2dkjA: undetectable	3nxuB-2dkjA: 21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SPK_B_TPVB100_1 (HIV-1 PROTEASE)	2dkj	SERINE HYDROXYMETHYLTRANSFE RASE (Thermus thermophilus)	5 / 9	ARG A 358 LEU A 313 ASN A 311 VAL A 286 GLY A 203	SO4 A2520 (-2.9A) None None None None	1.24A	3spkA-2dkjA: undetectable	3spkA-2dkjA: 12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3U88_A_CHDA611_0 (MENIN)	2dkj	SERINE HYDROXYMETHYLTRANSFE RASE (Thermus thermophilus)	3 / 3	SER A 127 PHE A 131 LYS A 134	None	0.99A	3u88A-2dkjA: undetectable	3u88A-2dkjA: 22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FIA_A_0U9A601_1 (CHOLESTEROL 24-HYDROXYLASE)	2dkj	SERINE HYDROXYMETHYLTRANSFE RASE (Thermus thermophilus)	5 / 12	PHE A 82 ALA A 202 THR A 227 GLU A 273 ALA A 274	None	1.23A	4fiaA-2dkjA: undetectable	4fiaA-2dkjA: 25.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FIA_A_198A602_1 (CHOLESTEROL 24-HYDROXYLASE)	2dkj	SERINE HYDROXYMETHYLTRANSFE RASE (Thermus thermophilus)	5 / 12	PHE A 82 ALA A 202 THR A 227 GLU A 273 ALA A 274	None	1.23A	4fiaA-2dkjA: undetectable	4fiaA-2dkjA: 25.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KQ8_A_ASDA602_1 (CYTOCHROME P450 19A1)	2dkj	SERINE HYDROXYMETHYLTRANSFE RASE (Thermus thermophilus)	5 / 10	ILE A 251 ALA A 100 VAL A 219 MET A 198 LEU A 237	None	1.32A	4kq8A-2dkjA: 0.0	4kq8A-2dkjA: 21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PCL_B_SAMB301_0 (O-METHYLTRANSFERASE FAMILY PROTEIN)	2dkj	SERINE HYDROXYMETHYLTRANSFE RASE (Thermus thermophilus)	5 / 12	GLN A 90 LEU A 260 GLY A 234 ALA A 199 ASN A 98	None None None PLP A 510 (-3.4A) PLP A 510 ( 4.5A)	1.27A	4pclB-2dkjA: 4.3	4pclB-2dkjA: 20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QRC_A_0LIA802_2 (FIBROBLAST GROWTH FACTOR RECEPTOR 4)	2dkj	SERINE HYDROXYMETHYLTRANSFE RASE (Thermus thermophilus)	4 / 8	LEU A 28 VAL A 339 ALA A 378 LEU A 297	None	0.83A	4qrcA-2dkjA: undetectable	4qrcA-2dkjA: 23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UBE_A_2FAA401_2 (ADENOSINE KINASE)	2dkj	SERINE HYDROXYMETHYLTRANSFE RASE (Thermus thermophilus)	4 / 4	ALA A 268 VAL A 89 GLY A 234 THR A 224	None	1.11A	4ubeA-2dkjA: undetectable	4ubeA-2dkjA: 24.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ZJZ_B_BEZB601_0 (BENZOATE-COENZYME A LIGASE)	2dkj	SERINE HYDROXYMETHYLTRANSFE RASE (Thermus thermophilus)	5 / 8	ALA A 119 PRO A 345 VAL A 143 GLY A 120 ALA A 173	None	1.42A	4zjzB-2dkjA: 4.9	4zjzB-2dkjA: 22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B58_A_ACTA608_0 (FUMARATE REDUCTASE FLAVOPROTEIN SUBUNIT)	2dkj	SERINE HYDROXYMETHYLTRANSFE RASE (Thermus thermophilus)	3 / 3	GLY A 368 THR A 370 GLU A 373	None	0.60A	6b58A-2dkjA: undetectable	6b58A-2dkjA: 23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BM5_A_SAMA1301_0 (METHIONINE SYNTHASE)	2dkj	SERINE HYDROXYMETHYLTRANSFE RASE (Thermus thermophilus)	5 / 11	ASP A 68 PRO A 56 ARG A 59 GLU A 261 ALA A 270	None	1.47A	6bm5A-2dkjA: 0.0	6bm5A-2dkjA: 22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6R2E_B_FFOB403_0 (THYMIDYLATE SYNTHASE)	2dkj	SERINE HYDROXYMETHYLTRANSFE RASE (Thermus thermophilus)	5 / 10	ILE A 236 LEU A 214 ASP A 240 LEU A 243 GLY A 244	None	1.48A	6r2eB-2dkjA: undetectable	6r2eB-2dkjA: 20.95

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1DFO_A_FFOA1002_0","SERINE HYDROXYMETHYLTRANSFERASE","2dkj","SERINE HYDROXYMETHYLTRANSFERASE","Thermus thermophilus",8,"LEU A 117;GLY A 120;HIS A 122;LEU A 123;VAL A 129;SER A 172;ALA A 173;ARG A 358","None;None;PLP A 510 (-3.5A);None;None;PLP A 510 ( 3.2A);None;SO4 A2520 (-2.9A)","0.46A","1dfoA-2dkjA:60.5","1dfoA-2dkjA:59.76"],["1DFO_A_FFOA1002_0","SERINE HYDROXYMETHYLTRANSFERASE","2dkj","SERINE HYDROXYMETHYLTRANSFERASE","Thermus thermophilus",7,"LEU A 117;GLY A 120;HIS A 122;SER A 172;ALA A 173;ASN A 342;ARG A 358","None;None;PLP A 510 (-3.5A);PLP A 510 ( 3.2A);None;None;SO4 A2520 (-2.9A)","0.83A","1dfoA-2dkjA:60.5","1dfoA-2dkjA:59.76"],["1DFO_A_FFOA1002_1","SERINE HYDROXYMETHYLTRANSFERASE","2dkj","SERINE HYDROXYMETHYLTRANSFERASE","Thermus thermophilus",5,"GLU A  53;TYR A  60;TYR A  61;PHE A 252;PRO A 253","None","0.33A","1dfoB-2dkjA:61.9","1dfoB-2dkjA:59.76"],["1DFO_B_FFOB2002_0","SERINE HYDROXYMETHYLTRANSFERASE","2dkj","SERINE HYDROXYMETHYLTRANSFERASE","Thermus thermophilus",5,"GLU A  53;TYR A  60;TYR A  61;PHE A 252;PRO A 253","None","0.33A","1dfoA-2dkjA:60.5","1dfoA-2dkjA:59.76"],["1DFO_B_FFOB2002_1","SERINE HYDROXYMETHYLTRANSFERASE","2dkj","SERINE HYDROXYMETHYLTRANSFERASE","Thermus thermophilus",8,"LEU A 117;GLY A 120;HIS A 122;LEU A 123;VAL A 129;SER A 172;ALA A 173;ARG A 358","None;None;PLP A 510 (-3.5A);None;None;PLP A 510 ( 3.2A);None;SO4 A2520 (-2.9A)","0.47A","1dfoB-2dkjA:61.9","1dfoB-2dkjA:59.76"],["1DFO_B_FFOB2002_1","SERINE HYDROXYMETHYLTRANSFERASE","2dkj","SERINE HYDROXYMETHYLTRANSFERASE","Thermus thermophilus",7,"LEU A 117;GLY A 120;HIS A 122;SER A 172;ALA A 173;ASN A 342;ARG A 358","None;None;PLP A 510 (-3.5A);PLP A 510 ( 3.2A);None;None;SO4 A2520 (-2.9A)","0.84A","1dfoB-2dkjA:61.9","1dfoB-2dkjA:59.76"],["1DFO_C_FFOC3002_1","SERINE HYDROXYMETHYLTRANSFERASE","2dkj","SERINE HYDROXYMETHYLTRANSFERASE","Thermus thermophilus",8,"LEU A 117;GLY A 120;HIS A 122;LEU A 123;VAL A 129;SER A 172;ALA A 173;ARG A 358","None;None;PLP A 510 (-3.5A);None;None;PLP A 510 ( 3.2A);None;SO4 A2520 (-2.9A)","0.46A","1dfoC-2dkjA:61.9","1dfoC-2dkjA:59.76"],["1DFO_C_FFOC3002_1","SERINE HYDROXYMETHYLTRANSFERASE","2dkj","SERINE HYDROXYMETHYLTRANSFERASE","Thermus thermophilus",7,"LEU A 117;GLY A 120;HIS A 122;SER A 172;ALA A 173;ASN A 342;ARG A 358","None;None;PLP A 510 (-3.5A);PLP A 510 ( 3.2A);None;None;SO4 A2520 (-2.9A)","0.83A","1dfoC-2dkjA:61.9","1dfoC-2dkjA:59.76"],["1DFO_C_FFOC3002_2","SERINE HYDROXYMETHYLTRANSFERASE","2dkj","SERINE HYDROXYMETHYLTRANSFERASE","Thermus thermophilus",5,"GLU A  53;TYR A  60;TYR A  61;PHE A 252;PRO A 253","None","0.33A","1dfoD-2dkjA:60.5","1dfoD-2dkjA:59.76"],["1DFO_D_FFOD4002_0","SERINE HYDROXYMETHYLTRANSFERASE","2dkj","SERINE HYDROXYMETHYLTRANSFERASE","Thermus thermophilus",5,"GLU A  53;TYR A  60;TYR A  61;PHE A 252;PRO A 253","None","0.33A","1dfoC-2dkjA:61.9","1dfoC-2dkjA:59.76"],["1DFO_D_FFOD4002_1","SERINE HYDROXYMETHYLTRANSFERASE","2dkj","SERINE HYDROXYMETHYLTRANSFERASE","Thermus thermophilus",8,"LEU A 117;GLY A 120;HIS A 122;LEU A 123;VAL A 129;SER A 172;ALA A 173;ARG A 358","None;None;PLP A 510 (-3.5A);None;None;PLP A 510 ( 3.2A);None;SO4 A2520 (-2.9A)","0.47A","1dfoD-2dkjA:60.5","1dfoD-2dkjA:59.76"],["1DFO_D_FFOD4002_1","SERINE HYDROXYMETHYLTRANSFERASE","2dkj","SERINE HYDROXYMETHYLTRANSFERASE","Thermus thermophilus",7,"LEU A 117;GLY A 120;HIS A 122;SER A 172;ALA A 173;ASN A 342;ARG A 358","None;None;PLP A 510 (-3.5A);PLP A 510 ( 3.2A);None;None;SO4 A2520 (-2.9A)","0.84A","1dfoD-2dkjA:60.5","1dfoD-2dkjA:59.76"],["1EQB_A_FFOA1293_0","SERINE HYDROXYMETHYLTRANSFERASE","2dkj","SERINE HYDROXYMETHYLTRANSFERASE","Thermus thermophilus",8,"LEU A 117;GLY A 120;HIS A 122;LEU A 123;VAL A 129;SER A 172;ALA A 173;ARG A 358","None;None;PLP A 510 (-3.5A);None;None;PLP A 510 ( 3.2A);None;SO4 A2520 (-2.9A)","0.45A","1eqbA-2dkjA:60.3","1eqbA-2dkjA:59.52"],["1EQB_A_FFOA1293_0","SERINE HYDROXYMETHYLTRANSFERASE","2dkj","SERINE HYDROXYMETHYLTRANSFERASE","Thermus thermophilus",6,"LEU A 117;GLY A 120;SER A 172;ALA A 173;ASN A 342;ARG A 358","None;None;PLP A 510 ( 3.2A);None;None;SO4 A2520 (-2.9A)","0.83A","1eqbA-2dkjA:60.3","1eqbA-2dkjA:59.52"],["1EQB_A_FFOA1293_1","SERINE HYDROXYMETHYLTRANSFERASE","2dkj","SERINE HYDROXYMETHYLTRANSFERASE","Thermus thermophilus",3,"GLU A  53;TYR A  60;PHE A 252","None","0.39A","1eqbB-2dkjA:61.9","1eqbB-2dkjA:59.52"],["1EQB_A_GLYA1292_0","SERINE HYDROXYMETHYLTRANSFERASE","2dkj","SERINE HYDROXYMETHYLTRANSFERASE","Thermus thermophilus",6,"SER A  31;HIS A 122;SER A 172;HIS A 200;LYS A 226;ARG A 358","SO4 A2520 (-2.7A);PLP A 510 (-3.5A);PLP A 510 ( 3.2A);SO4 A2520 ( 4.0A);PLP A 510 ( 1.3A);SO4 A2520 (-2.9A)","0.49A","1eqbA-2dkjA:60.3;1eqbB-2dkjA:61.9","1eqbA-2dkjA:59.52;1eqbB-2dkjA:59.52"],["1EQB_B_FFOB2293_0","SERINE HYDROXYMETHYLTRANSFERASE","2dkj","SERINE HYDROXYMETHYLTRANSFERASE","Thermus thermophilus",3,"GLU A  53;TYR A  60;PHE A 252","None","0.38A","1eqbA-2dkjA:60.3","1eqbA-2dkjA:59.52"],["1EQB_B_FFOB2293_1","SERINE HYDROXYMETHYLTRANSFERASE","2dkj","SERINE HYDROXYMETHYLTRANSFERASE","Thermus thermophilus",8,"LEU A 117;GLY A 120;HIS A 122;LEU A 123;VAL A 129;SER A 172;ALA A 173;ARG A 358","None;None;PLP A 510 (-3.5A);None;None;PLP A 510 ( 3.2A);None;SO4 A2520 (-2.9A)","0.45A","1eqbB-2dkjA:61.9","1eqbB-2dkjA:59.52"],["1EQB_B_FFOB2293_1","SERINE HYDROXYMETHYLTRANSFERASE","2dkj","SERINE HYDROXYMETHYLTRANSFERASE","Thermus thermophilus",6,"LEU A 117;GLY A 120;SER A 172;ALA A 173;ASN A 342;ARG A 358","None;None;PLP A 510 ( 3.2A);None;None;SO4 A2520 (-2.9A)","0.82A","1eqbB-2dkjA:61.9","1eqbB-2dkjA:59.52"],["1EQB_B_GLYB2292_0","SERINE HYDROXYMETHYLTRANSFERASE","2dkj","SERINE HYDROXYMETHYLTRANSFERASE","Thermus thermophilus",6,"SER A  31;HIS A 122;SER A 172;HIS A 200;LYS A 226;ARG A 358","SO4 A2520 (-2.7A);PLP A 510 (-3.5A);PLP A 510 ( 3.2A);SO4 A2520 ( 4.0A);PLP A 510 ( 1.3A);SO4 A2520 (-2.9A)","0.49A","1eqbA-2dkjA:60.3;1eqbB-2dkjA:61.9","1eqbA-2dkjA:59.52;1eqbB-2dkjA:59.52"],["1EQB_C_FFOC3293_1","SERINE HYDROXYMETHYLTRANSFERASE","2dkj","SERINE HYDROXYMETHYLTRANSFERASE","Thermus thermophilus",8,"LEU A 117;GLY A 120;HIS A 122;LEU A 123;VAL A 129;SER A 172;ALA A 173;ARG A 358","None;None;PLP A 510 (-3.5A);None;None;PLP A 510 ( 3.2A);None;SO4 A2520 (-2.9A)","0.45A","1eqbC-2dkjA:61.8","1eqbC-2dkjA:59.52"],["1EQB_C_FFOC3293_1","SERINE HYDROXYMETHYLTRANSFERASE","2dkj","SERINE HYDROXYMETHYLTRANSFERASE","Thermus thermophilus",6,"LEU A 117;GLY A 120;SER A 172;ALA A 173;ASN A 342;ARG A 358","None;None;PLP A 510 ( 3.2A);None;None;SO4 A2520 (-2.9A)","0.83A","1eqbC-2dkjA:61.8","1eqbC-2dkjA:59.52"],["1EQB_C_FFOC3293_2","SERINE HYDROXYMETHYLTRANSFERASE","2dkj","SERINE HYDROXYMETHYLTRANSFERASE","Thermus thermophilus",3,"GLU A  53;TYR A  60;PHE A 252","None","0.38A","1eqbD-2dkjA:60.6","1eqbD-2dkjA:59.52"],["1EQB_C_GLYC3292_0","SERINE HYDROXYMETHYLTRANSFERASE","2dkj","SERINE HYDROXYMETHYLTRANSFERASE","Thermus thermophilus",6,"SER A  31;HIS A 122;SER A 172;HIS A 200;LYS A 226;ARG A 358","SO4 A2520 (-2.7A);PLP A 510 (-3.5A);PLP A 510 ( 3.2A);SO4 A2520 ( 4.0A);PLP A 510 ( 1.3A);SO4 A2520 (-2.9A)","0.49A","1eqbC-2dkjA:61.8;1eqbD-2dkjA:60.6","1eqbC-2dkjA:59.52;1eqbD-2dkjA:59.52"],["1EQB_D_FFOD4293_0","SERINE HYDROXYMETHYLTRANSFERASE","2dkj","SERINE HYDROXYMETHYLTRANSFERASE","Thermus thermophilus",3,"GLU A  53;TYR A  60;PHE A 252","None","0.38A","1eqbC-2dkjA:61.8","1eqbC-2dkjA:59.52"],["1EQB_D_FFOD4293_1","SERINE HYDROXYMETHYLTRANSFERASE","2dkj","SERINE HYDROXYMETHYLTRANSFERASE","Thermus thermophilus",8,"LEU A 117;GLY A 120;HIS A 122;LEU A 123;VAL A 129;SER A 172;ALA A 173;ARG A 358","None;None;PLP A 510 (-3.5A);None;None;PLP A 510 ( 3.2A);None;SO4 A2520 (-2.9A)","0.45A","1eqbD-2dkjA:60.6","1eqbD-2dkjA:59.52"],["1EQB_D_FFOD4293_1","SERINE HYDROXYMETHYLTRANSFERASE","2dkj","SERINE HYDROXYMETHYLTRANSFERASE","Thermus thermophilus",6,"LEU A 117;GLY A 120;SER A 172;ALA A 173;ASN A 342;ARG A 358","None;None;PLP A 510 ( 3.2A);None;None;SO4 A2520 (-2.9A)","0.83A","1eqbD-2dkjA:60.6","1eqbD-2dkjA:59.52"],["1EQB_D_GLYD4292_0","SERINE HYDROXYMETHYLTRANSFERASE","2dkj","SERINE HYDROXYMETHYLTRANSFERASE","Thermus thermophilus",6,"SER A  31;HIS A 122;SER A 172;HIS A 200;LYS A 226;ARG A 358","SO4 A2520 (-2.7A);PLP A 510 (-3.5A);PLP A 510 ( 3.2A);SO4 A2520 ( 4.0A);PLP A 510 ( 1.3A);SO4 A2520 (-2.9A)","0.50A","1eqbC-2dkjA:61.8;1eqbD-2dkjA:60.6","1eqbC-2dkjA:59.52;1eqbD-2dkjA:59.52"],["1GEB_A_CAMA418_0","CYTOCHROME P450-CAM","2dkj","SERINE HYDROXYMETHYLTRANSFERASE","Thermus thermophilus",5,"PHE A 314;VAL A 377;ILE A 337;VAL A 339;ILE A 359","None","1.29A","1gebA-2dkjA:undetectable","1gebA-2dkjA:22.59"],["1YA4_B_CTXB2_2","CES1 PROTEIN","2dkj","SERINE HYDROXYMETHYLTRANSFERASE","Thermus thermophilus",4,"LEU A 400;PRO A 407;ILE A 364;LEU A  26","None","1.13A","1ya4B-2dkjA:undetectable","1ya4B-2dkjA:22.78"],["2AVV_E_MK1E902_4","POL POLYPROTEIN","2dkj","SERINE HYDROXYMETHYLTRANSFERASE","Thermus thermophilus",3,"ARG A 394;VAL A 377;GLY A 360","None","0.61A","2avvE-2dkjA:undetectable","2avvE-2dkjA:13.02"],["2PGF_A_ADNA501_1","ADENOSINE DEAMINASE","2dkj","SERINE HYDROXYMETHYLTRANSFERASE","Thermus thermophilus",5,"PHE A 131;GLY A 126;HIS A 125;HIS A 122;SER A  95","None;None;PLP A 510 ( 4.7A);PLP A 510 (-3.5A);PLP A 510 (-2.7A)","1.34A","2pgfA-2dkjA:undetectable","2pgfA-2dkjA:23.91"],["2VMY_A_FFOA505_0","SERINE HYDROXYMETHYLTRANSFERASE","2dkj","SERINE HYDROXYMETHYLTRANSFERASE","Thermus thermophilus",5,"GLU A  53;TYR A  60;TYR A  61;PHE A 252;PRO A 253","None","0.24A","2vmyA-2dkjA:61.7","2vmyA-2dkjA:66.01"],["2VMY_A_FFOA505_1","SERINE HYDROXYMETHYLTRANSFERASE","2dkj","SERINE HYDROXYMETHYLTRANSFERASE","Thermus thermophilus",8,"LEU A 117;GLY A 120;HIS A 122;LEU A 123;VAL A 129;SER A 172;ALA A 173;ARG A 358","None;None;PLP A 510 (-3.5A);None;None;PLP A 510 ( 3.2A);None;SO4 A2520 (-2.9A)","0.47A","2vmyB-2dkjA:60.4","2vmyB-2dkjA:66.01"],["2VMY_A_GLYA502_0","SERINE HYDROXYMETHYLTRANSFERASE","2dkj","SERINE HYDROXYMETHYLTRANSFERASE","Thermus thermophilus",5,"SER A  31;HIS A 122;HIS A 200;LYS A 226;ARG A 358","SO4 A2520 (-2.7A);PLP A 510 (-3.5A);SO4 A2520 ( 4.0A);PLP A 510 ( 1.3A);SO4 A2520 (-2.9A)","0.50A","2vmyA-2dkjA:61.7;2vmyB-2dkjA:60.4","2vmyA-2dkjA:66.01;2vmyB-2dkjA:66.01"],["2VMY_B_FFOB505_0","SERINE HYDROXYMETHYLTRANSFERASE","2dkj","SERINE HYDROXYMETHYLTRANSFERASE","Thermus thermophilus",5,"HIS A 122;LEU A 123;VAL A 129;SER A 172;ASN A 342","PLP A 510 (-3.5A);None;None;PLP A 510 ( 3.2A);None","0.96A","2vmyA-2dkjA:61.7","2vmyA-2dkjA:66.01"],["2VMY_B_FFOB505_0","SERINE HYDROXYMETHYLTRANSFERASE","2dkj","SERINE HYDROXYMETHYLTRANSFERASE","Thermus thermophilus",9,"LEU A 117;GLY A 120;HIS A 122;LEU A 123;VAL A 129;SER A 172;ALA A 173;ASN A 340;ARG A 358","None;None;PLP A 510 (-3.5A);None;None;PLP A 510 ( 3.2A);None;None;SO4 A2520 (-2.9A)","0.57A","2vmyA-2dkjA:61.7","2vmyA-2dkjA:66.01"],["2VMY_B_FFOB505_1","SERINE HYDROXYMETHYLTRANSFERASE","2dkj","SERINE HYDROXYMETHYLTRANSFERASE","Thermus thermophilus",4,"GLU A  53;TYR A  60;TYR A  61;PHE A 252","None","0.33A","2vmyB-2dkjA:60.4","2vmyB-2dkjA:66.01"],["2VMY_B_GLYB502_0","SERINE HYDROXYMETHYLTRANSFERASE","2dkj","SERINE HYDROXYMETHYLTRANSFERASE","Thermus thermophilus",6,"SER A  31;HIS A 122;SER A 172;HIS A 200;LYS A 226;ARG A 358","SO4 A2520 (-2.7A);PLP A 510 (-3.5A);PLP A 510 ( 3.2A);SO4 A2520 ( 4.0A);PLP A 510 ( 1.3A);SO4 A2520 (-2.9A)","0.49A","2vmyA-2dkjA:61.7;2vmyB-2dkjA:60.4","2vmyA-2dkjA:66.01;2vmyB-2dkjA:66.01"],["2XF3_B_J01B500_1","ORF12","2dkj","SERINE HYDROXYMETHYLTRANSFERASE","Thermus thermophilus",5,"VAL A 305;ILE A 344;LEU A 385;GLY A 325;ALA A 328","None","1.34A","2xf3B-2dkjA:0.3","2xf3B-2dkjA:24.59"],["2XFS_B_J01B500_1","ORF12","2dkj","SERINE HYDROXYMETHYLTRANSFERASE","Thermus thermophilus",5,"VAL A 305;ILE A 344;LEU A 385;GLY A 325;ALA A 328","None","1.32A","2xfsB-2dkjA:0.0","2xfsB-2dkjA:24.59"],["2XH9_B_J01B1436_1","ORF12","2dkj","SERINE HYDROXYMETHYLTRANSFERASE","Thermus thermophilus",5,"VAL A 305;ILE A 344;LEU A 385;GLY A 325;ALA A 328","None","1.35A","2xh9B-2dkjA:0.3","2xh9B-2dkjA:24.59"],["3A2Q_A_ACAA602_1","6-AMINOHEXANOATE-CYCLIC-DIMER HYDROLASE","2dkj","SERINE HYDROXYMETHYLTRANSFERASE","Thermus thermophilus",4,"ASN A  88;ALA A  74;ALA A  78;GLN A  90","None","0.69A","3a2qA-2dkjA:undetectable","3a2qA-2dkjA:26.05"],["3EM4_V_DR7V100_2","PROTEASE","2dkj","SERINE HYDROXYMETHYLTRANSFERASE","Thermus thermophilus",5,"ASP A 197;GLY A 233;GLY A 234;LEU A 235;VAL A 101","PLP A 510 (-2.8A);None;None;None;None","1.08A","3em4V-2dkjA:undetectable","3em4V-2dkjA:14.00"],["3KP6_A_SALA3002_1","TRANSCRIPTIONAL REGULATOR TCAR;TRANSCRIPTIONAL REGULATOR TCAR","2dkj","SERINE HYDROXYMETHYLTRANSFERASE","Thermus thermophilus",5,"VAL A 101;LEU A 105;ILE A 236;VAL A 219;LEU A 243","None","1.14A","3kp6A-2dkjA:undetectable;3kp6B-2dkjA:undetectable","3kp6A-2dkjA:16.38;3kp6B-2dkjA:16.38"],["3LB3_A_4CHA191_0","DEHALOPEROXIDASE A","2dkj","SERINE HYDROXYMETHYLTRANSFERASE","Thermus thermophilus",4,"PHE A 183;TYR A 141;HIS A 125;VAL A 196","None;None;PLP A 510 ( 4.7A);None","1.18A","3lb3A-2dkjA:undetectable","3lb3A-2dkjA:16.46"],["3NXU_B_RITB600_1","CYTOCHROME P450 3A4","2dkj","SERINE HYDROXYMETHYLTRANSFERASE","Thermus thermophilus",5,"PHE A 314;MET A 374;THR A 306;ILE A 364;ALA A 363","None","1.08A","3nxuB-2dkjA:undetectable","3nxuB-2dkjA:21.54"],["3SPK_B_TPVB100_1","HIV-1 PROTEASE;HIV-1 PROTEASE","2dkj","SERINE HYDROXYMETHYLTRANSFERASE","Thermus thermophilus",5,"ARG A 358;LEU A 313;ASN A 311;VAL A 286;GLY A 203","SO4 A2520 (-2.9A);None;None;None;None","1.24A","3spkA-2dkjA:undetectable","3spkA-2dkjA:12.53"],["3U88_A_CHDA611_0","MENIN","2dkj","SERINE HYDROXYMETHYLTRANSFERASE","Thermus thermophilus",3,"SER A 127;PHE A 131;LYS A 134","None","0.99A","3u88A-2dkjA:undetectable","3u88A-2dkjA:22.99"],["4FIA_A_0U9A601_1","CHOLESTEROL 24-HYDROXYLASE","2dkj","SERINE HYDROXYMETHYLTRANSFERASE","Thermus thermophilus",5,"PHE A  82;ALA A 202;THR A 227;GLU A 273;ALA A 274","None","1.23A","4fiaA-2dkjA:undetectable","4fiaA-2dkjA:25.50"],["4FIA_A_198A602_1","CHOLESTEROL 24-HYDROXYLASE","2dkj","SERINE HYDROXYMETHYLTRANSFERASE","Thermus thermophilus",5,"PHE A  82;ALA A 202;THR A 227;GLU A 273;ALA A 274","None","1.23A","4fiaA-2dkjA:undetectable","4fiaA-2dkjA:25.50"],["4KQ8_A_ASDA602_1","CYTOCHROME P450 19A1","2dkj","SERINE HYDROXYMETHYLTRANSFERASE","Thermus thermophilus",5,"ILE A 251;ALA A 100;VAL A 219;MET A 198;LEU A 237","None","1.32A","4kq8A-2dkjA:0.0","4kq8A-2dkjA:21.12"],["4PCL_B_SAMB301_0","O-METHYLTRANSFERASE FAMILY PROTEIN","2dkj","SERINE HYDROXYMETHYLTRANSFERASE","Thermus thermophilus",5,"GLN A  90;LEU A 260;GLY A 234;ALA A 199;ASN A  98","None;None;None;PLP A 510 (-3.4A);PLP A 510 ( 4.5A)","1.27A","4pclB-2dkjA:4.3","4pclB-2dkjA:20.15"],["4QRC_A_0LIA802_2","FIBROBLAST GROWTH FACTOR RECEPTOR 4","2dkj","SERINE HYDROXYMETHYLTRANSFERASE","Thermus thermophilus",4,"LEU A  28;VAL A 339;ALA A 378;LEU A 297","None","0.83A","4qrcA-2dkjA:undetectable","4qrcA-2dkjA:23.92"],["4UBE_A_2FAA401_2","ADENOSINE KINASE","2dkj","SERINE HYDROXYMETHYLTRANSFERASE","Thermus thermophilus",4,"ALA A 268;VAL A  89;GLY A 234;THR A 224","None","1.11A","4ubeA-2dkjA:undetectable","4ubeA-2dkjA:24.15"],["4ZJZ_B_BEZB601_0","BENZOATE-COENZYME A LIGASE","2dkj","SERINE HYDROXYMETHYLTRANSFERASE","Thermus thermophilus",5,"ALA A 119;PRO A 345;VAL A 143;GLY A 120;ALA A 173","None","1.42A","4zjzB-2dkjA:4.9","4zjzB-2dkjA:22.68"],["6B58_A_ACTA608_0","FUMARATE REDUCTASE FLAVOPROTEIN SUBUNIT","2dkj","SERINE HYDROXYMETHYLTRANSFERASE","Thermus thermophilus",3,"GLY A 368;THR A 370;GLU A 373","None","0.60A","6b58A-2dkjA:undetectable","6b58A-2dkjA:23.45"],["6BM5_A_SAMA1301_0","METHIONINE SYNTHASE","2dkj","SERINE HYDROXYMETHYLTRANSFERASE","Thermus thermophilus",5,"ASP A  68;PRO A  56;ARG A  59;GLU A 261;ALA A 270","None","1.47A","6bm5A-2dkjA:0.0","6bm5A-2dkjA:22.46"],["6R2E_B_FFOB403_0","THYMIDYLATE SYNTHASE","2dkj","SERINE HYDROXYMETHYLTRANSFERASE","Thermus thermophilus",5,"ILE A 236;LEU A 214;ASP A 240;LEU A 243;GLY A 244","None","1.48A","6r2eB-2dkjA:undetectable","6r2eB-2dkjA:20.95"]]