SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2dkw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZX_A_TRPA602_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2dkw HYPOTHETICAL PROTEIN
KIAA1240
(Homo
sapiens) 		4 / 8 PHE A 116
GLU A 115
LEU A 119
ILE A 123
 None
 0.91A 2azxA-2dkwA:
undetectable		 2azxA-2dkwA:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_C_KLNC1498_1
(CYTOCHROME P450 3A4)		 2dkw HYPOTHETICAL PROTEIN
KIAA1240
(Homo
sapiens) 		5 / 12 ARG A  29
LEU A  69
PHE A  68
ILE A 107
ALA A 106
 None
 1.11A 2v0mC-2dkwA:
undetectable		 2v0mC-2dkwA:
15.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWU_A_ACAA18_1
(WTFP-TAG,GP41)		 2dkw HYPOTHETICAL PROTEIN
KIAA1240
(Homo
sapiens) 		5 / 12 GLY A   4
SER A   3
LYS A   1
LEU A 119
GLU A 121
 None
 1.16A 5nwuA-2dkwA:
undetectable		 5nwuA-2dkwA:
15.38