SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2dkx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2HRC_A_CHDA702_0 (FERROCHELATASE)	2dkx	SAM POINTED DOMAIN-CONTAINING ETS TRANSCRIPTION FACTOR (Homo sapiens)	4 / 7	MET A 63 PRO A 24 VAL A 32 TRP A 27	None	1.37A	2hrcA-2dkxA: undetectable	2hrcA-2dkxA: 16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2PNJ_A_CHDA502_0 (FERROCHELATASE, MITOCHONDRIAL)	2dkx	SAM POINTED DOMAIN-CONTAINING ETS TRANSCRIPTION FACTOR (Homo sapiens)	4 / 5	MET A 63 PRO A 24 VAL A 32 TRP A 27	None	1.33A	2pnjA-2dkxA: undetectable	2pnjA-2dkxA: 16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KLA_A_CHDA501_0 (FERROCHELATASE, MITOCHONDRIAL)	2dkx	SAM POINTED DOMAIN-CONTAINING ETS TRANSCRIPTION FACTOR (Homo sapiens)	4 / 7	ARG A 71 VAL A 32 MET A 25 TRP A 27	None	1.39A	4klaA-2dkxA: undetectable	4klaA-2dkxA: 16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KMM_A_CHDA503_0 (FERROCHELATASE, MITOCHONDRIAL)	2dkx	SAM POINTED DOMAIN-CONTAINING ETS TRANSCRIPTION FACTOR (Homo sapiens)	4 / 7	MET A 63 PRO A 24 VAL A 32 TRP A 27	None	1.30A	4kmmA-2dkxA: undetectable	4kmmA-2dkxA: 13.90

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2HRC_A_CHDA702_0","FERROCHELATASE","2dkx","SAM POINTED DOMAIN-CONTAINING ETS TRANSCRIPTION FACTOR","Homo sapiens",4,"MET A  63;PRO A  24;VAL A  32;TRP A  27","None","1.37A","2hrcA-2dkxA:undetectable","2hrcA-2dkxA:16.72"],["2PNJ_A_CHDA502_0","FERROCHELATASE, MITOCHONDRIAL","2dkx","SAM POINTED DOMAIN-CONTAINING ETS TRANSCRIPTION FACTOR","Homo sapiens",4,"MET A  63;PRO A  24;VAL A  32;TRP A  27","None","1.33A","2pnjA-2dkxA:undetectable","2pnjA-2dkxA:16.67"],["4KLA_A_CHDA501_0","FERROCHELATASE, MITOCHONDRIAL","2dkx","SAM POINTED DOMAIN-CONTAINING ETS TRANSCRIPTION FACTOR","Homo sapiens",4,"ARG A  71;VAL A  32;MET A  25;TRP A  27","None","1.39A","4klaA-2dkxA:undetectable","4klaA-2dkxA:16.72"],["4KMM_A_CHDA503_0","FERROCHELATASE, MITOCHONDRIAL","2dkx","SAM POINTED DOMAIN-CONTAINING ETS TRANSCRIPTION FACTOR","Homo sapiens",4,"MET A  63;PRO A  24;VAL A  32;TRP A  27","None","1.30A","4kmmA-2dkxA:undetectable","4kmmA-2dkxA:13.90"]]