SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2dl2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_I_BEZI518_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 2dl2 PROTEIN (MHC CLASS I
NK CELL RECEPTOR
PRECURSOR (P58
NATURAL KILLER CELL
RECEPTOR CLONE
CL-43))
(Homo
sapiens) 		4 / 7 ILE A  52
GLY A  53
PHE A  64
ASN A  63
 None
 0.93A 1oniG-2dl2A:
undetectable
1oniI-2dl2A:
undetectable		 1oniG-2dl2A:
19.12
1oniI-2dl2A:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OPX_A_DXCA1002_0
(ALDEHYDE
DEHYDROGENASE A)		 2dl2 PROTEIN (MHC CLASS I
NK CELL RECEPTOR
PRECURSOR (P58
NATURAL KILLER CELL
RECEPTOR CLONE
CL-43))
(Homo
sapiens) 		3 / 3 GLY A  75
ARG A  41
TYR A 186
 None
 0.83A 2opxA-2dl2A:
undetectable		 2opxA-2dl2A:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DR2_A_PARA1609_1
(16S RRNA
30S RIBOSOMAL
PROTEIN S9
30S RIBOSOMAL
PROTEIN S10)		 2dl2 PROTEIN (MHC CLASS I
NK CELL RECEPTOR
PRECURSOR (P58
NATURAL KILLER CELL
RECEPTOR CLONE
CL-43))
(Homo
sapiens) 		3 / 3 TYR A  80
ARG A  78
SER A  94
 None
 0.94A 4dr2I-2dl2A:
undetectable
4dr2J-2dl2A:
undetectable		 4dr2I-2dl2A:
19.40
4dr2J-2dl2A:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OR0_B_NPSB603_1
(SERUM ALBUMIN)		 2dl2 PROTEIN (MHC CLASS I
NK CELL RECEPTOR
PRECURSOR (P58
NATURAL KILLER CELL
RECEPTOR CLONE
CL-43))
(Homo
sapiens) 		5 / 11 LEU A  39
ARG A  41
VAL A  24
LEU A  49
LEU A  10
 None
 1.16A 4or0B-2dl2A:
undetectable		 4or0B-2dl2A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OTW_A_DB8A1101_2
(RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-3)		 2dl2 PROTEIN (MHC CLASS I
NK CELL RECEPTOR
PRECURSOR (P58
NATURAL KILLER CELL
RECEPTOR CLONE
CL-43))
(Homo
sapiens) 		3 / 3 LEU A  97
LEU A  49
ASN A  63
 None
 0.73A 4otwA-2dl2A:
undetectable		 4otwA-2dl2A:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 2dl2 PROTEIN (MHC CLASS I
NK CELL RECEPTOR
PRECURSOR (P58
NATURAL KILLER CELL
RECEPTOR CLONE
CL-43))
(Homo
sapiens) 		5 / 10 ALA A 169
THR A 170
ALA A 120
VAL A 124
GLY A 173
 None
 0.99A 4qvyK-2dl2A:
undetectable
4qvyL-2dl2A:
undetectable		 4qvyK-2dl2A:
22.75
4qvyL-2dl2A:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 2dl2 PROTEIN (MHC CLASS I
NK CELL RECEPTOR
PRECURSOR (P58
NATURAL KILLER CELL
RECEPTOR CLONE
CL-43))
(Homo
sapiens) 		5 / 10 ALA A 169
THR A 170
ALA A 120
VAL A 124
GLY A 173
 None
 0.99A 4qvyY-2dl2A:
undetectable
4qvyZ-2dl2A:
undetectable		 4qvyY-2dl2A:
22.75
4qvyZ-2dl2A:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_D_29SD601_2
(ESTROGEN RECEPTOR)		 2dl2 PROTEIN (MHC CLASS I
NK CELL RECEPTOR
PRECURSOR (P58
NATURAL KILLER CELL
RECEPTOR CLONE
CL-43))
(Homo
sapiens) 		3 / 3 LEU A  39
ASP A  47
ILE A  25
 None
 0.66A 4xi3D-2dl2A:
undetectable		 4xi3D-2dl2A:
24.29