SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2dlu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CEV_A_GAIA407_0
(PROTEIN (ARGINASE))		 2dlu INAD-LIKE PROTEIN
(Homo
sapiens) 		4 / 6 ARG A  96
HIS A  62
LEU A  64
ASP A  61
 None
 1.23A 4cevA-2dluA:
undetectable
4cevB-2dluA:
undetectable		 4cevA-2dluA:
17.29
4cevB-2dluA:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CEV_C_GAIC409_0
(PROTEIN (ARGINASE))		 2dlu INAD-LIKE PROTEIN
(Homo
sapiens) 		4 / 6 ASP A  61
ARG A  96
HIS A  62
LEU A  64
 None
 1.22A 4cevA-2dluA:
undetectable
4cevC-2dluA:
undetectable		 4cevA-2dluA:
17.29
4cevC-2dluA:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CEV_D_GAID410_0
(PROTEIN (ARGINASE))		 2dlu INAD-LIKE PROTEIN
(Homo
sapiens) 		4 / 6 ARG A  96
HIS A  62
LEU A  64
ASP A  61
 None
 1.20A 4cevD-2dluA:
undetectable
4cevE-2dluA:
undetectable		 4cevD-2dluA:
17.29
4cevE-2dluA:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CEV_F_GAIF411_0
(PROTEIN (ARGINASE))		 2dlu INAD-LIKE PROTEIN
(Homo
sapiens) 		4 / 6 ARG A  96
HIS A  62
LEU A  64
ASP A  61
 None
 1.20A 4cevE-2dluA:
undetectable
4cevF-2dluA:
undetectable		 4cevE-2dluA:
17.29
4cevF-2dluA:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0S_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 2dlu INAD-LIKE PROTEIN
(Homo
sapiens) 		5 / 12 VAL A  19
LEU A  83
ILE A  45
VAL A  42
VAL A  40
 None
 0.97A 4y0sA-2dluA:
undetectable		 4y0sA-2dluA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZB_C_ACTC401_0
(PROTON-GATED ION
CHANNEL)		 2dlu INAD-LIKE PROTEIN
(Homo
sapiens) 		4 / 7 ILE A  32
PHE A  30
VAL A  79
ILE A  66
 None
 0.83A 4zzbC-2dluA:
undetectable
4zzbD-2dluA:
undetectable		 4zzbC-2dluA:
16.77
4zzbD-2dluA:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWX_A_SAMA301_0
(GLYCINE SARCOSINE
N-METHYLTRANSFERASE)		 2dlu INAD-LIKE PROTEIN
(Homo
sapiens) 		5 / 12 ALA A  51
GLY A  49
GLY A  27
SER A  26
GLY A  55
 None
 1.00A 5gwxA-2dluA:
undetectable		 5gwxA-2dluA:
20.29