SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2dlz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_B_SVRB512_2
(PHOSPHOLIPASE A2)		 2dlz PROTEIN VAV-2
(Homo
sapiens) 		4 / 7 VAL A  68
LYS A  66
ILE A  65
LEU A  32
 None
 0.85A 3bjwB-2dlzA:
undetectable		 3bjwB-2dlzA:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_3
(PHOSPHOLIPASE A2)		 2dlz PROTEIN VAV-2
(Homo
sapiens) 		4 / 7 VAL A  68
LYS A  66
ILE A  65
LEU A  32
 None
 0.90A 3bjwF-2dlzA:
undetectable		 3bjwF-2dlzA:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G8I_A_RO7A1_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR ALPHA)		 2dlz PROTEIN VAV-2
(Homo
sapiens) 		4 / 7 LEU A  31
LEU A 104
VAL A  62
LEU A  88
 None
 0.94A 3g8iA-2dlzA:
undetectable		 3g8iA-2dlzA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y03_A_SALA801_1
(PROTEIN POLYBROMO-1)		 2dlz PROTEIN VAV-2
(Homo
sapiens) 		4 / 7 ILE A  76
LEU A  85
ALA A  53
ILE A  65
 None
 0.84A 4y03A-2dlzA:
undetectable		 4y03A-2dlzA:
21.05