SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2dm9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CTR_A_TFPA153_1
(CALMODULIN)		 2dm9 V-TYPE ATP SYNTHASE
SUBUNIT E
(Pyrococcus
horikoshii) 		5 / 9 GLU A 104
ILE A 150
GLU A 140
GLU A 144
VAL A 148
 None
 1.14A 1ctrA-2dm9A:
undetectable		 1ctrA-2dm9A:
26.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_B_BEZB12_0
(CES1 PROTEIN)		 2dm9 V-TYPE ATP SYNTHASE
SUBUNIT E
(Pyrococcus
horikoshii) 		4 / 4 GLY A 160
SER A 126
VAL A 106
LEU A  94
 None
 1.28A 1yajB-2dm9A:
undetectable		 1yajB-2dm9A:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WQ4_A_ACTA403_0
(TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE)		 2dm9 V-TYPE ATP SYNTHASE
SUBUNIT E
(Pyrococcus
horikoshii) 		3 / 3 VAL A 106
LEU A 110
VAL A 162
 None
 0.41A 4wq4A-2dm9A:
undetectable		 4wq4A-2dm9A:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMW_F_RBFF201_1
(GLYOXALASE/BLEOMYCIN
RESISANCE
PROTEIN/DIOXYGENASE)		 2dm9 V-TYPE ATP SYNTHASE
SUBUNIT E
(Pyrococcus
horikoshii) 		4 / 7 LEU A  87
VAL A 162
TYR A 102
SER A 126
 None
 1.20A 5umwA-2dm9A:
undetectable
5umwF-2dm9A:
undetectable		 5umwA-2dm9A:
13.07
5umwF-2dm9A:
13.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXN_B_SAMB901_0
(DIPHTHAMIDE
BIOSYNTHESIS ENZYME
DPH2)		 2dm9 V-TYPE ATP SYNTHASE
SUBUNIT E
(Pyrococcus
horikoshii) 		5 / 12 LEU A 133
GLY A 132
LYS A 111
VAL A 148
ILE A 150
 None
 1.45A 6bxnB-2dm9A:
3.1		 6bxnB-2dm9A:
23.31