SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2dmg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS6_A_DXCA75_0
(PPCA)		 2dmg KIAA1228 PROTEIN
(Homo
sapiens) 		4 / 8 ILE A  37
LEU A 111
LYS A  68
GLY A 101
 None
 1.00A 1os6A-2dmgA:
undetectable		 1os6A-2dmgA:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T86_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 2dmg KIAA1228 PROTEIN
(Homo
sapiens) 		4 / 8 THR A  70
THR A  64
VAL A  97
VAL A  48
 None
 0.73A 1t86A-2dmgA:
undetectable		 1t86A-2dmgA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FUM_D_MIXD3539_2
(PROBABLE
SERINE/THREONINE-PRO
TEIN KINASE PKNB)		 2dmg KIAA1228 PROTEIN
(Homo
sapiens) 		3 / 3 VAL A  66
VAL A  48
ASP A 107
 None
 0.68A 2fumD-2dmgA:
undetectable		 2fumD-2dmgA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SEL_X_DXCX75_0
(CYTOCHROME C7)		 2dmg KIAA1228 PROTEIN
(Homo
sapiens) 		4 / 8 ILE A  37
LEU A 111
LYS A  68
GLY A 101
 None
 0.91A 3selX-2dmgA:
undetectable		 3selX-2dmgA:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SJ1_X_DXCX75_0
(CYTOCHROME C7)		 2dmg KIAA1228 PROTEIN
(Homo
sapiens) 		4 / 6 ILE A  37
LEU A 111
LYS A  68
GLY A 101
 None
 0.89A 3sj1X-2dmgA:
undetectable		 3sj1X-2dmgA:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A3P_A_ACTA1223_0
(UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 15)		 2dmg KIAA1228 PROTEIN
(Homo
sapiens) 		4 / 5 ASP A  94
THR A  92
LEU A 115
LYS A 113
 None
 1.27A 4a3pA-2dmgA:
undetectable		 4a3pA-2dmgA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HB8_A_DXCA75_0
(PPCA)		 2dmg KIAA1228 PROTEIN
(Homo
sapiens) 		4 / 8 ILE A  37
LEU A 111
LYS A  68
GLY A 101
 None
 0.74A 4hb8A-2dmgA:
undetectable		 4hb8A-2dmgA:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HBF_A_DXCA75_0
(PPCA)		 2dmg KIAA1228 PROTEIN
(Homo
sapiens) 		4 / 7 ILE A  37
LEU A 111
LYS A  68
GLY A 101
 None
 0.97A 4hbfA-2dmgA:
undetectable		 4hbfA-2dmgA:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HC3_A_DXCA75_0
(PPCA)		 2dmg KIAA1228 PROTEIN
(Homo
sapiens) 		4 / 7 ILE A  37
LEU A 111
LYS A  68
GLY A 101
 None
 0.92A 4hc3A-2dmgA:
undetectable		 4hc3A-2dmgA:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNW_B_RTZB602_1
(CYTOCHROME P450 2D6)		 2dmg KIAA1228 PROTEIN
(Homo
sapiens) 		5 / 12 GLY A  11
LEU A 133
ALA A  32
VAL A  97
VAL A 116
 None
 1.12A 4wnwB-2dmgA:
undetectable		 4wnwB-2dmgA:
16.63