SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2dmh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9Q_A_CHDA459_0
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 2dmh MYOFERLIN
(Homo
sapiens) 		4 / 6 ASP A 126
LEU A 127
VAL A 128
ILE A 129
 None
 0.91A 1s9qA-2dmhA:
undetectable		 1s9qA-2dmhA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FXR_A_ASCA3001_0
(LYSR TYPE REGULATOR
OF TSAMBCD)		 2dmh MYOFERLIN
(Homo
sapiens) 		4 / 8 ILE A  19
ASN A  50
PRO A  29
PRO A  27
 None
 0.83A 3fxrA-2dmhA:
undetectable		 3fxrA-2dmhA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKD_A_CYZA266_2
(GLUTAMATE RECEPTOR 2)		 2dmh MYOFERLIN
(Homo
sapiens) 		4 / 5 ILE A  64
PRO A  65
SER A 139
GLY A  63
 None
 1.00A 3tkdB-2dmhA:
undetectable		 3tkdB-2dmhA:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKD_B_CYZB267_1
(GLUTAMATE RECEPTOR 2)		 2dmh MYOFERLIN
(Homo
sapiens) 		4 / 5 ILE A  64
PRO A  65
SER A 139
GLY A  63
 None
 0.99A 3tkdA-2dmhA:
undetectable		 3tkdA-2dmhA:
23.38