SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2dn7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EGV_B_SAMB1400_0 (UPF0088 PROTEIN AQ_165)	2dn7	RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE F (Homo sapiens)	5 / 12	ASN A 83 GLY A 88 GLY A 7 LEU A 38 LEU A 37	None	0.98A	2egvB-2dn7A: undetectable	2egvB-2dn7A: 19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U9U_A_ACTA1502_0 (NA(+)-TRANSLOCATING NADH-QUINONE REDUCTASE SUBUNIT F)	2dn7	RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE F (Homo sapiens)	4 / 5	GLY A 86 ALA A 85 GLY A 7 PRO A 8	None	0.88A	4u9uA-2dn7A: undetectable	4u9uA-2dn7A: 16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U9U_B_ACTB1502_0 (NA(+)-TRANSLOCATING NADH-QUINONE REDUCTASE SUBUNIT F)	2dn7	RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE F (Homo sapiens)	4 / 5	GLY A 86 ALA A 85 GLY A 7 PRO A 8	None	0.87A	4u9uB-2dn7A: undetectable	4u9uB-2dn7A: 16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZCP_P_CHDP306_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	2dn7	RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE F (Homo sapiens)	4 / 6	GLN A 62 PHE A 57 LEU A 42 PHE A 77	None	1.12A	5zcpP-2dn7A: undetectable 5zcpW-2dn7A: undetectable	5zcpP-2dn7A: 18.77 5zcpW-2dn7A: 19.63

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2EGV_B_SAMB1400_0","UPF0088 PROTEIN AQ_165","2dn7","RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE F","Homo sapiens",5,"ASN A  83;GLY A  88;GLY A   7;LEU A  38;LEU A  37","None","0.98A","2egvB-2dn7A:undetectable","2egvB-2dn7A:19.05"],["4U9U_A_ACTA1502_0","NA(+)-TRANSLOCATING NADH-QUINONE REDUCTASE SUBUNIT F","2dn7","RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE F","Homo sapiens",4,"GLY A  86;ALA A  85;GLY A   7;PRO A   8","None","0.88A","4u9uA-2dn7A:undetectable","4u9uA-2dn7A:16.01"],["4U9U_B_ACTB1502_0","NA(+)-TRANSLOCATING NADH-QUINONE REDUCTASE SUBUNIT F","2dn7","RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE F","Homo sapiens",4,"GLY A  86;ALA A  85;GLY A   7;PRO A   8","None","0.87A","4u9uB-2dn7A:undetectable","4u9uB-2dn7A:16.01"],["5ZCP_P_CHDP306_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","2dn7","RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE F","Homo sapiens",4,"GLN A  62;PHE A  57;LEU A  42;PHE A  77","None","1.12A","5zcpP-2dn7A:undetectable;5zcpW-2dn7A:undetectable","5zcpP-2dn7A:18.77;5zcpW-2dn7A:19.63"]]