SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2dna'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4R29_A_SAMA301_0 (UNCHARACTERIZED PROTEIN)	2dna	UNNAMED PROTEIN PRODUCT (Mus musculus)	5 / 12	ALA A 36 ALA A 28 MET A 29 GLY A 30 PHE A 31	None	1.14A	4r29A-2dnaA: undetectable	4r29A-2dnaA: 17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4R29_B_SAMB301_0 (UNCHARACTERIZED PROTEIN)	2dna	UNNAMED PROTEIN PRODUCT (Mus musculus)	5 / 12	ALA A 36 ALA A 28 MET A 29 GLY A 30 PHE A 31	None	1.07A	4r29B-2dnaA: undetectable	4r29B-2dnaA: 17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4R29_C_SAMC301_0 (UNCHARACTERIZED PROTEIN)	2dna	UNNAMED PROTEIN PRODUCT (Mus musculus)	5 / 12	ALA A 36 ALA A 28 MET A 29 GLY A 30 PHE A 31	None	1.11A	4r29C-2dnaA: undetectable	4r29C-2dnaA: 17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4R29_D_SAMD301_0 (UNCHARACTERIZED PROTEIN)	2dna	UNNAMED PROTEIN PRODUCT (Mus musculus)	5 / 12	ALA A 36 ALA A 28 MET A 29 GLY A 30 PHE A 31	None	1.06A	4r29D-2dnaA: undetectable	4r29D-2dnaA: 17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6MA7_A_TPFA602_0 (CYTOCHROME P450 3A4)	2dna	UNNAMED PROTEIN PRODUCT (Mus musculus)	4 / 7	SER A 58 ALA A 36 ILE A 42 ALA A 43	None	0.82A	6ma7A-2dnaA: undetectable	6ma7A-2dnaA: 24.42

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["4R29_A_SAMA301_0","UNCHARACTERIZED PROTEIN","2dna","UNNAMED PROTEIN PRODUCT","Mus musculus",5,"ALA A  36;ALA A  28;MET A  29;GLY A  30;PHE A  31","None","1.14A","4r29A-2dnaA:undetectable","4r29A-2dnaA:17.37"],["4R29_B_SAMB301_0","UNCHARACTERIZED PROTEIN","2dna","UNNAMED PROTEIN PRODUCT","Mus musculus",5,"ALA A  36;ALA A  28;MET A  29;GLY A  30;PHE A  31","None","1.07A","4r29B-2dnaA:undetectable","4r29B-2dnaA:17.37"],["4R29_C_SAMC301_0","UNCHARACTERIZED PROTEIN","2dna","UNNAMED PROTEIN PRODUCT","Mus musculus",5,"ALA A  36;ALA A  28;MET A  29;GLY A  30;PHE A  31","None","1.11A","4r29C-2dnaA:undetectable","4r29C-2dnaA:17.37"],["4R29_D_SAMD301_0","UNCHARACTERIZED PROTEIN","2dna","UNNAMED PROTEIN PRODUCT","Mus musculus",5,"ALA A  36;ALA A  28;MET A  29;GLY A  30;PHE A  31","None","1.06A","4r29D-2dnaA:undetectable","4r29D-2dnaA:17.37"],["6MA7_A_TPFA602_0","CYTOCHROME P450 3A4","2dna","UNNAMED PROTEIN PRODUCT","Mus musculus",4,"SER A  58;ALA A  36;ILE A  42;ALA A  43","None","0.82A","6ma7A-2dnaA:undetectable","6ma7A-2dnaA:24.42"]]