SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2dnw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BU8_A_TF4A1379_1
(PYRUVATE
DEHYDROGENASE KINASE
ISOENZYME 2)		 2dnw ACYL CARRIER PROTEIN
(Homo
sapiens) 		4 / 8 LEU A  24
ILE A  81
ILE A  55
ILE A  56
 None
 0.82A 2bu8A-2dnwA:
undetectable		 2bu8A-2dnwA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X9G_A_LYAA1270_2
(PTERIDINE REDUCTASE)		 2dnw ACYL CARRIER PROTEIN
(Homo
sapiens) 		3 / 3 MET A  76
VAL A  23
GLU A  60
 None
 0.86A 2x9gA-2dnwA:
undetectable		 2x9gA-2dnwA:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AQ7_A_LEUA902_0
(LEUCINE--TRNA LIGASE)		 2dnw ACYL CARRIER PROTEIN
(Homo
sapiens) 		4 / 7 LEU A  45
ASP A  44
SER A  39
GLU A  33
 None
 1.15A 4aq7A-2dnwA:
undetectable		 4aq7A-2dnwA:
8.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		 2dnw ACYL CARRIER PROTEIN
(Homo
sapiens) 		4 / 8 VAL A  23
GLN A  52
PRO A  78
ILE A  81
 None
 1.07A 6hzpA-2dnwA:
undetectable		 6hzpA-2dnwA:
11.82