SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2dnx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R2V_D_ACTD37_0
(GCN4 LEUCINE ZIPPER)		 2dnx SYNTAXIN-12
(Homo
sapiens) 		3 / 3 LYS A  34
ARG A 112
VAL A 114
 None
 0.92A 2r2vC-2dnxA:
undetectable
2r2vD-2dnxA:
undetectable		 2r2vC-2dnxA:
17.89
2r2vD-2dnxA:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TJY_A_BEZA304_0
(4-HYDROXY-TETRAHYDRO
DIPICOLINATE
REDUCTASE)		 2dnx SYNTAXIN-12
(Homo
sapiens) 		3 / 3 MET A  37
GLU A 116
ARG A 113
 None
 0.77A 5tjyA-2dnxA:
undetectable		 5tjyA-2dnxA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TJZ_A_BEZA302_0
(4-HYDROXY-TETRAHYDRO
DIPICOLINATE
REDUCTASE)		 2dnx SYNTAXIN-12
(Homo
sapiens) 		3 / 3 MET A  37
GLU A 116
ARG A 113
 None
 0.83A 5tjzA-2dnxA:
undetectable		 5tjzA-2dnxA:
20.66