SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2doc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IJX_H_HCZH800_1 (GLUTAMATE RECEPTOR 2)	2doc	NEURAL CELL ADHESION MOLECULE 2 (Homo sapiens)	4 / 5	PRO A 112 SER A 114 LEU A 29 SER A 30	None	1.41A	3ijxH-2docA: undetectable	3ijxH-2docA: 25.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ILU_H_HFZH800_1 (GLUTAMATE RECEPTOR 2)	2doc	NEURAL CELL ADHESION MOLECULE 2 (Homo sapiens)	4 / 5	PRO A 112 SER A 114 LEU A 29 SER A 30	None	1.48A	3iluH-2docA: undetectable	3iluH-2docA: 25.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SUF_B_SUEB1201_3 (NS3 PROTEASE, NS4A PROTEIN)	2doc	NEURAL CELL ADHESION MOLECULE 2 (Homo sapiens)	4 / 5	SER A 37 PRO A 21 TYR A 22 VAL A 91	None	1.40A	3sufC-2docA: undetectable	3sufC-2docA: 20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5M0O_A_EPAA502_1 (TERMINAL OLEFIN-FORMING FATTY ACID DECARBOXYLASE)	2doc	NEURAL CELL ADHESION MOLECULE 2 (Homo sapiens)	5 / 10	PRO A 18 ILE A 66 ARG A 68 VAL A 91 PRO A 41	None	1.34A	5m0oA-2docA: undetectable	5m0oA-2docA: 13.52

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3IJX_H_HCZH800_1","GLUTAMATE RECEPTOR 2","2doc","NEURAL CELL ADHESION MOLECULE 2","Homo sapiens",4,"PRO A 112;SER A 114;LEU A  29;SER A  30","None","1.41A","3ijxH-2docA:undetectable","3ijxH-2docA:25.85"],["3ILU_H_HFZH800_1","GLUTAMATE RECEPTOR 2","2doc","NEURAL CELL ADHESION MOLECULE 2","Homo sapiens",4,"PRO A 112;SER A 114;LEU A  29;SER A  30","None","1.48A","3iluH-2docA:undetectable","3iluH-2docA:25.85"],["3SUF_B_SUEB1201_3","NS3 PROTEASE, NS4A PROTEIN;NS3 PROTEASE, NS4A PROTEIN","2doc","NEURAL CELL ADHESION MOLECULE 2","Homo sapiens",4,"SER A  37;PRO A  21;TYR A  22;VAL A  91","None","1.40A","3sufC-2docA:undetectable","3sufC-2docA:20.19"],["5M0O_A_EPAA502_1","TERMINAL OLEFIN-FORMING FATTY ACID DECARBOXYLASE","2doc","NEURAL CELL ADHESION MOLECULE 2","Homo sapiens",5,"PRO A  18;ILE A  66;ARG A  68;VAL A  91;PRO A  41","None","1.34A","5m0oA-2docA:undetectable","5m0oA-2docA:13.52"]]