SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2dos'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_A_CHDA1501_0
(FERROCHELATASE)		 2dos ATAXIN-3
(Homo
sapiens) 		5 / 12 LEU A  33
PHE A  28
LEU A  91
VAL A 165
VAL A  86
 None
 1.21A 1hrkA-2dosA:
undetectable		 1hrkA-2dosA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_B_CHDB1605_0
(FERROCHELATASE)		 2dos ATAXIN-3
(Homo
sapiens) 		5 / 12 LEU A  33
PHE A  28
LEU A  91
VAL A 165
VAL A  86
 None
 1.18A 2hrcB-2dosA:
undetectable		 2hrcB-2dosA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_A_CHDA501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2dos ATAXIN-3
(Homo
sapiens) 		5 / 12 LEU A  33
PHE A  28
LEU A  91
VAL A 165
VAL A  86
 None
 1.10A 2po5A-2dosA:
undetectable		 2po5A-2dosA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_B_CHDB501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2dos ATAXIN-3
(Homo
sapiens) 		5 / 11 LEU A  33
PHE A  28
LEU A  91
VAL A 165
VAL A  86
 None
 1.10A 2po5B-2dosA:
undetectable		 2po5B-2dosA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO7_A_CHDA501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2dos ATAXIN-3
(Homo
sapiens) 		5 / 12 LEU A  33
PHE A  28
LEU A  91
VAL A 165
VAL A  86
 None
 1.21A 2po7A-2dosA:
undetectable		 2po7A-2dosA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OJ4_A_DIFA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2dos ATAXIN-3
(Homo
sapiens) 		4 / 8 CYH A  18
LEU A  84
LEU A  89
VAL A 165
 None
 0.92A 4oj4A-2dosA:
undetectable		 4oj4A-2dosA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HQA_A_ACRA705_2
(ALPHA-GLUCOSIDASE)		 2dos ATAXIN-3
(Homo
sapiens) 		4 / 8 ASN A  82
TRP A 120
PHE A  75
THR A  60
 None
 1.41A 5hqaA-2dosA:
undetectable		 5hqaA-2dosA:
14.08