SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2dpg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DVT_A_FLPA125_1
(TRANSTHYRETIN)		 2dpg GLUCOSE 6-PHOSPHATE
DEHYDROGENASE
(Leuconostoc
mesenteroides) 		4 / 8 LEU A 381
ALA A 367
LEU A 369
LEU A 320
 None
 0.94A 1dvtA-2dpgA:
undetectable
1dvtB-2dpgA:
undetectable		 1dvtA-2dpgA:
13.40
1dvtB-2dpgA:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I00_A_D16A315_1
(THYMIDYLATE SYNTHASE)		 2dpg GLUCOSE 6-PHOSPHATE
DEHYDROGENASE
(Leuconostoc
mesenteroides) 		5 / 9 ILE A 146
ASP A 163
LEU A 160
GLY A 124
PHE A 123
 None
 1.39A 1i00A-2dpgA:
undetectable		 1i00A-2dpgA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_D_BEZD507_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 2dpg GLUCOSE 6-PHOSPHATE
DEHYDROGENASE
(Leuconostoc
mesenteroides) 		4 / 7 PHE A 332
ALA A 249
ILE A 349
ILE A 188
 None
 0.79A 1oniD-2dpgA:
undetectable
1oniF-2dpgA:
1.0		 1oniD-2dpgA:
16.46
1oniF-2dpgA:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_A_SAMA801_1
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 2dpg GLUCOSE 6-PHOSPHATE
DEHYDROGENASE
(Leuconostoc
mesenteroides) 		4 / 6 TYR A 333
ASP A 479
ASN A 477
GLU A 458
 None
 1.32A 1rjdA-2dpgA:
6.4		 1rjdA-2dpgA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TV8_B_SAMB2501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 2dpg GLUCOSE 6-PHOSPHATE
DEHYDROGENASE
(Leuconostoc
mesenteroides) 		4 / 7 TYR A 179
GLU A 416
THR A 411
VAL A 185
 None
 1.09A 1tv8B-2dpgA:
2.1		 1tv8B-2dpgA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQT_A_AINA596_1
(LACTOPEROXIDASE)		 2dpg GLUCOSE 6-PHOSPHATE
DEHYDROGENASE
(Leuconostoc
mesenteroides) 		4 / 6 HIS A 178
GLU A 147
PHE A 123
PRO A 120
 None
 1.32A 2qqtA-2dpgA:
undetectable		 2qqtA-2dpgA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7P_A_SALA1001_1
(LYSR-TYPE REGULATORY
PROTEIN)		 2dpg GLUCOSE 6-PHOSPHATE
DEHYDROGENASE
(Leuconostoc
mesenteroides) 		4 / 6 MET A 465
SER A 215
ARG A 346
TRP A 481
 None
 1.49A 2y7pA-2dpgA:
1.7		 2y7pA-2dpgA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZH_A_D2VA602_2
(CYTOCHROME P450 2R1)		 2dpg GLUCOSE 6-PHOSPHATE
DEHYDROGENASE
(Leuconostoc
mesenteroides) 		3 / 3 LEU A  35
GLU A 416
ILE A 419
 None
 0.54A 3czhA-2dpgA:
undetectable		 3czhA-2dpgA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_A_CHDA153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 2dpg GLUCOSE 6-PHOSPHATE
DEHYDROGENASE
(Leuconostoc
mesenteroides) 		4 / 5 ILE A 146
THR A 422
PHE A  10
TYR A 115
 None
 1.23A 3em0A-2dpgA:
0.7		 3em0A-2dpgA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GCL_A_AINA609_1
(LACTOPEROXIDASE)		 2dpg GLUCOSE 6-PHOSPHATE
DEHYDROGENASE
(Leuconostoc
mesenteroides) 		4 / 6 HIS A 178
GLU A 147
PHE A 123
PRO A 120
 None
 1.35A 3gclA-2dpgA:
undetectable		 3gclA-2dpgA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_G_TFPG201_1
(PROTEIN S100-A4)		 2dpg GLUCOSE 6-PHOSPHATE
DEHYDROGENASE
(Leuconostoc
mesenteroides) 		5 / 9 GLY A 435
PHE A 269
ILE A 237
PHE A 332
PHE A 322
 None
 1.42A 3ko0F-2dpgA:
0.1
3ko0G-2dpgA:
0.0		 3ko0F-2dpgA:
14.91
3ko0G-2dpgA:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LB3_B_4CHB192_0
(DEHALOPEROXIDASE A)		 2dpg GLUCOSE 6-PHOSPHATE
DEHYDROGENASE
(Leuconostoc
mesenteroides) 		4 / 6 PHE A 284
PHE A 442
TYR A 275
VAL A 334
 None
 1.27A 3lb3B-2dpgA:
undetectable		 3lb3B-2dpgA:
13.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5V_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 2dpg GLUCOSE 6-PHOSPHATE
DEHYDROGENASE
(Leuconostoc
mesenteroides) 		4 / 7 ARG A 335
VAL A 285
PHE A 315
GLU A 468
 None
 1.36A 3n5vA-2dpgA:
undetectable
3n5vB-2dpgA:
undetectable		 3n5vA-2dpgA:
22.18
3n5vB-2dpgA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5V_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 2dpg GLUCOSE 6-PHOSPHATE
DEHYDROGENASE
(Leuconostoc
mesenteroides) 		4 / 7 PHE A 315
GLU A 468
ARG A 335
VAL A 285
 None
 1.39A 3n5vA-2dpgA:
undetectable
3n5vB-2dpgA:
undetectable		 3n5vA-2dpgA:
22.18
3n5vB-2dpgA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QG2_B_CP6B709_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 2dpg GLUCOSE 6-PHOSPHATE
DEHYDROGENASE
(Leuconostoc
mesenteroides) 		5 / 11 ILE A 126
PHE A  11
ILE A  99
LEU A 130
THR A  87
 None
None
None
None
NAP  A 799 ( 4.8A)
 1.23A 3qg2B-2dpgA:
2.6		 3qg2B-2dpgA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFA_A_SAMA406_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE N)		 2dpg GLUCOSE 6-PHOSPHATE
DEHYDROGENASE
(Leuconostoc
mesenteroides) 		5 / 12 PHE A  10
PRO A 414
SER A  25
VAL A   8
ILE A 113
 None
 1.36A 3rfaA-2dpgA:
3.0		 3rfaA-2dpgA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROD_D_NCAD302_0
(NICOTINAMIDE
N-METHYLTRANSFERASE)		 2dpg GLUCOSE 6-PHOSPHATE
DEHYDROGENASE
(Leuconostoc
mesenteroides) 		4 / 7 LEU A 457
ASP A 453
ALA A 455
TYR A 450
 None
 1.08A 3rodD-2dpgA:
undetectable		 3rodD-2dpgA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3V_A_TOPA193_1
(DIHYDROFOLATE
REDUCTASE)		 2dpg GLUCOSE 6-PHOSPHATE
DEHYDROGENASE
(Leuconostoc
mesenteroides) 		4 / 5 ASP A 163
LEU A 160
ILE A 126
PHE A 122
 None
None
None
NAP  A 799 ( 4.7A)
 0.97A 3s3vA-2dpgA:
1.8		 3s3vA-2dpgA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2dpg GLUCOSE 6-PHOSPHATE
DEHYDROGENASE
(Leuconostoc
mesenteroides) 		4 / 7 ARG A 335
VAL A 285
PHE A 315
GLU A 468
 None
 1.38A 3ufoA-2dpgA:
undetectable
3ufoB-2dpgA:
undetectable		 3ufoA-2dpgA:
22.18
3ufoB-2dpgA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DU2_B_LDPB501_1
(CYTOCHROME P450 BM3
VARIANT B7)		 2dpg GLUCOSE 6-PHOSPHATE
DEHYDROGENASE
(Leuconostoc
mesenteroides) 		4 / 7 ALA A 317
PHE A 315
ALA A 287
ALA A 469
 None
 0.90A 4du2B-2dpgA:
undetectable		 4du2B-2dpgA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2dpg GLUCOSE 6-PHOSPHATE
DEHYDROGENASE
(Leuconostoc
mesenteroides) 		4 / 6 ARG A 335
VAL A 285
PHE A 315
GLU A 468
 None
 1.48A 4imwA-2dpgA:
undetectable
4imwB-2dpgA:
undetectable		 4imwA-2dpgA:
22.18
4imwB-2dpgA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J4V_A_SVRA301_1
(NUCLEOCAPSID PROTEIN)		 2dpg GLUCOSE 6-PHOSPHATE
DEHYDROGENASE
(Leuconostoc
mesenteroides) 		5 / 11 GLY A 318
VAL A 334
MET A 242
PHE A 442
ILE A 446
 None
 1.36A 4j4vA-2dpgA:
0.3		 4j4vA-2dpgA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J4V_D_SVRD301_1
(NUCLEOCAPSID PROTEIN)		 2dpg GLUCOSE 6-PHOSPHATE
DEHYDROGENASE
(Leuconostoc
mesenteroides) 		5 / 11 GLY A 318
VAL A 334
MET A 242
PHE A 442
ILE A 446
 None
 1.43A 4j4vD-2dpgA:
0.0
4j4vE-2dpgA:
0.3		 4j4vD-2dpgA:
19.22
4j4vE-2dpgA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_A_ADNA2414_1
(RNA-DIRECTED RNA
POLYMERASE L)		 2dpg GLUCOSE 6-PHOSPHATE
DEHYDROGENASE
(Leuconostoc
mesenteroides) 		4 / 6 GLU A   3
PHE A  39
PHE A 106
HIS A  38
 None
 1.11A 4uciA-2dpgA:
undetectable		 4uciA-2dpgA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2dpg GLUCOSE 6-PHOSPHATE
DEHYDROGENASE
(Leuconostoc
mesenteroides) 		4 / 7 PHE A 315
GLU A 468
ARG A 335
VAL A 285
 None
 1.48A 5ad4A-2dpgA:
undetectable
5ad4B-2dpgA:
undetectable		 5ad4A-2dpgA:
22.18
5ad4B-2dpgA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_C_ADNC502_2
(ADENOSYLHOMOCYSTEINA
SE)		 2dpg GLUCOSE 6-PHOSPHATE
DEHYDROGENASE
(Leuconostoc
mesenteroides) 		4 / 5 THR A 422
THR A   9
HIS A  84
LEU A 130
 None
 1.21A 5axaC-2dpgA:
4.6		 5axaC-2dpgA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CPR_B_SAMB402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 2dpg GLUCOSE 6-PHOSPHATE
DEHYDROGENASE
(Leuconostoc
mesenteroides) 		5 / 12 GLY A 463
ALA A 341
PHE A 315
SER A 336
GLU A 303
 None
 1.47A 5cprB-2dpgA:
undetectable		 5cprB-2dpgA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESG_A_1YNA701_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2dpg GLUCOSE 6-PHOSPHATE
DEHYDROGENASE
(Leuconostoc
mesenteroides) 		4 / 4 LEU A  57
TYR A 115
PRO A  24
ILE A  62
 None
 1.31A 5esgA-2dpgA:
undetectable		 5esgA-2dpgA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I8F_A_ML1A211_1
(PHENOLIC OXIDATIVE
COUPLING PROTEIN)		 2dpg GLUCOSE 6-PHOSPHATE
DEHYDROGENASE
(Leuconostoc
mesenteroides) 		4 / 6 VAL A 449
LYS A 454
ALA A 455
VAL A 280
 None
 1.05A 5i8fA-2dpgA:
undetectable		 5i8fA-2dpgA:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_G_ACTG702_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 2dpg GLUCOSE 6-PHOSPHATE
DEHYDROGENASE
(Leuconostoc
mesenteroides) 		3 / 3 GLY A 231
THR A 314
ASN A 312
 None
 0.64A 5odiG-2dpgA:
2.8		 5odiG-2dpgA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U4S_A_BEZA301_0
(PUTATIVE SHORT CHAIN
DEHYDROGENASE)		 2dpg GLUCOSE 6-PHOSPHATE
DEHYDROGENASE
(Leuconostoc
mesenteroides) 		4 / 7 ASN A 142
ILE A 126
LEU A 130
LEU A 136
 None
 0.96A 5u4sA-2dpgA:
6.0		 5u4sA-2dpgA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U4S_B_BEZB301_0
(PUTATIVE SHORT CHAIN
DEHYDROGENASE)		 2dpg GLUCOSE 6-PHOSPHATE
DEHYDROGENASE
(Leuconostoc
mesenteroides) 		4 / 8 ASN A 142
ILE A 126
LEU A 130
LEU A 136
 None
 0.93A 5u4sB-2dpgA:
3.7		 5u4sB-2dpgA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNV_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2dpg GLUCOSE 6-PHOSPHATE
DEHYDROGENASE
(Leuconostoc
mesenteroides) 		4 / 6 ARG A 335
VAL A 285
PHE A 315
GLU A 468
 None
 1.35A 5unvA-2dpgA:
undetectable
5unvB-2dpgA:
undetectable		 5unvA-2dpgA:
22.18
5unvB-2dpgA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNV_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2dpg GLUCOSE 6-PHOSPHATE
DEHYDROGENASE
(Leuconostoc
mesenteroides) 		4 / 6 PHE A 315
GLU A 468
ARG A 335
VAL A 285
 None
 1.45A 5unvA-2dpgA:
undetectable
5unvB-2dpgA:
undetectable		 5unvA-2dpgA:
22.18
5unvB-2dpgA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_C_CHDC401_0
(BILE SALT HYDROLASE)		 2dpg GLUCOSE 6-PHOSPHATE
DEHYDROGENASE
(Leuconostoc
mesenteroides) 		4 / 8 LEU A 340
TYR A 460
LEU A 233
ALA A 232
 None
 0.82A 5y7pC-2dpgA:
undetectable		 5y7pC-2dpgA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YOD_F_BEZF201_0
(NS3 PROTEASE)		 2dpg GLUCOSE 6-PHOSPHATE
DEHYDROGENASE
(Leuconostoc
mesenteroides) 		4 / 5 ALA A  18
SER A 117
TYR A 115
TYR A 415
 None
NAP  A 799 ( 4.2A)
None
None
 1.45A 5yodF-2dpgA:
0.0		 5yodF-2dpgA:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CP4_A_CAMA422_0
(CYTOCHROME P450CAM)		 2dpg GLUCOSE 6-PHOSPHATE
DEHYDROGENASE
(Leuconostoc
mesenteroides) 		4 / 8 LEU A 180
VAL A 185
VAL A 212
VAL A 347
 None
 1.07A 6cp4A-2dpgA:
undetectable		 6cp4A-2dpgA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D9H_R_ADNR400_1
(CHIMERA PROTEIN OF
MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4 AND
ADENOSINE RECEPTOR
A1)		 2dpg GLUCOSE 6-PHOSPHATE
DEHYDROGENASE
(Leuconostoc
mesenteroides) 		5 / 10 VAL A 334
THR A 241
LEU A 233
ASN A 313
ILE A 446
 None
 1.21A 6d9hR-2dpgA:
undetectable		 6d9hR-2dpgA:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA825_0
(GEPHYRIN)		 2dpg GLUCOSE 6-PHOSPHATE
DEHYDROGENASE
(Leuconostoc
mesenteroides) 		3 / 3 LYS A 408
VAL A 403
ASP A 405
 None
 0.50A 6fgdA-2dpgA:
2.8		 6fgdA-2dpgA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2dpg GLUCOSE 6-PHOSPHATE
DEHYDROGENASE
(Leuconostoc
mesenteroides) 		3 / 3 ARG A 262
PHE A 168
PHE A 430
 None
 1.00A 6nknC-2dpgA:
undetectable
6nknJ-2dpgA:
undetectable		 6nknC-2dpgA:
19.83
6nknJ-2dpgA:
8.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6R2E_A_FFOA403_0
(THYMIDYLATE SYNTHASE)		 2dpg GLUCOSE 6-PHOSPHATE
DEHYDROGENASE
(Leuconostoc
mesenteroides) 		5 / 12 PHE A 284
ILE A 237
ASN A 240
LEU A 234
GLY A 231
 None
 1.21A 6r2eA-2dpgA:
undetectable		 6r2eA-2dpgA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6R2E_C_FFOC404_0
(THYMIDYLATE SYNTHASE)		 2dpg GLUCOSE 6-PHOSPHATE
DEHYDROGENASE
(Leuconostoc
mesenteroides) 		5 / 10 PHE A 284
ILE A 237
ASN A 240
LEU A 234
GLY A 231
 None
 1.18A 6r2eC-2dpgA:
undetectable		 6r2eC-2dpgA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6R2E_E_FFOE403_0
(THYMIDYLATE SYNTHASE)		 2dpg GLUCOSE 6-PHOSPHATE
DEHYDROGENASE
(Leuconostoc
mesenteroides) 		5 / 12 PHE A 284
ILE A 237
ASN A 240
LEU A 234
GLY A 231
 None
 1.18A 6r2eE-2dpgA:
undetectable		 6r2eE-2dpgA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6R2E_H_FFOH403_0
(THYMIDYLATE SYNTHASE)		 2dpg GLUCOSE 6-PHOSPHATE
DEHYDROGENASE
(Leuconostoc
mesenteroides) 		5 / 12 PHE A 284
ILE A 237
ASN A 240
LEU A 234
GLY A 231
 None
 1.18A 6r2eH-2dpgA:
undetectable		 6r2eH-2dpgA:
19.84