SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2dpk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_C_EAAC223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 2dpk SODIUM/CALCIUM
EXCHANGER 1
(Canis
lupus) 		4 / 8 GLY A 398
LEU A 401
VAL A 405
PHE A 375
 None
 1.01A 1gsfC-2dpkA:
undetectable		 1gsfC-2dpkA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC5_A_NCAA2001_0
(NAD-DEPENDENT
DEACETYLASE)		 2dpk SODIUM/CALCIUM
EXCHANGER 1
(Canis
lupus) 		4 / 7 ILE A 496
ASP A 499
ILE A 445
ASP A 421
 None
CA  A4001 (-2.7A)
None
CA  A1001 ( 2.5A)
 0.85A 1yc5A-2dpkA:
undetectable		 1yc5A-2dpkA:
20.88