SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2dqa'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJG_B_ADNB1502_1
(235AA LONG
HYPOTHETICAL
BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 2dqa LYSOZYME
(Ruditapes
philippinarum) 		4 / 7 LYS A  68
ASN A  64
PRO A   3
ALA A   2
 None
 1.35A 2ejgB-2dqaA:
undetectable		 2ejgB-2dqaA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_D_DVAD8_0
(GRAMICIDIN A)		 2dqa LYSOZYME
(Ruditapes
philippinarum) 		3 / 3 TRP A  46
VAL A  70
TRP A  56
 None
 1.33A 2xdcC-2dqaA:
undetectable
2xdcD-2dqaA:
undetectable		 2xdcC-2dqaA:
6.25
2xdcD-2dqaA:
6.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_F_DVAF8_0
(GRAMICIDIN A)		 2dqa LYSOZYME
(Ruditapes
philippinarum) 		3 / 3 TRP A  46
VAL A  70
TRP A  56
 None
 1.32A 2xdcE-2dqaA:
undetectable
2xdcF-2dqaA:
undetectable		 2xdcE-2dqaA:
6.25
2xdcF-2dqaA:
6.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_F_DVAF8_0
(VAL-GRAMICIDIN A)		 2dqa LYSOZYME
(Ruditapes
philippinarum) 		3 / 3 TRP A  46
VAL A  70
TRP A  56
 None
 1.31A 2y5mE-2dqaA:
undetectable
2y5mF-2dqaA:
undetectable		 2y5mE-2dqaA:
6.25
2y5mF-2dqaA:
6.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_D_DVAD8_0
(VAL-GRAMICIDIN A)		 2dqa LYSOZYME
(Ruditapes
philippinarum) 		3 / 3 TRP A  46
VAL A  70
TRP A  56
 None
 1.30A 2y6nC-2dqaA:
undetectable
2y6nD-2dqaA:
undetectable		 2y6nC-2dqaA:
6.25
2y6nD-2dqaA:
6.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_F_DVAF8_0
(VAL-GRAMICIDIN A)		 2dqa LYSOZYME
(Ruditapes
philippinarum) 		3 / 3 TRP A  46
VAL A  70
TRP A  56
 None
 1.30A 2y6nE-2dqaA:
undetectable
2y6nF-2dqaA:
undetectable		 2y6nE-2dqaA:
6.25
2y6nF-2dqaA:
6.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9R_A_ACTA700_0
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 2dqa LYSOZYME
(Ruditapes
philippinarum) 		4 / 6 GLY A  97
TYR A  81
GLU A  93
GLY A 100
 None
 1.09A 3e9rA-2dqaA:
undetectable		 3e9rA-2dqaA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9R_C_ACTC700_0
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 2dqa LYSOZYME
(Ruditapes
philippinarum) 		4 / 6 GLY A  97
TYR A  81
GLU A  93
GLY A 100
 None
 1.09A 3e9rC-2dqaA:
undetectable		 3e9rC-2dqaA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A3U_A_ACTA1358_0
(NADH:FLAVIN
OXIDOREDUCTASE/NADH
OXIDASE)		 2dqa LYSOZYME
(Ruditapes
philippinarum) 		5 / 9 ALA A   2
PRO A   3
GLN A   8
ASN A  64
SER A  67
 None
 1.36A 4a3uA-2dqaA:
undetectable		 4a3uA-2dqaA:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LRB_A_ACRA1003_1
(ALPHA-1,4 GLUCAN
PHOSPHORYLASE)		 2dqa LYSOZYME
(Ruditapes
philippinarum) 		4 / 6 GLU A  18
THR A 106
TYR A 109
TYR A  45
 None
 0.92A 5lrbA-2dqaA:
undetectable		 5lrbA-2dqaA:
7.97