SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2dqi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IG3_B_VIBB501_1
(THIAMIN
PYROPHOSPHOKINASE)		 2dqi LYSOZYME BINDING IG
KAPPA CHAIN V23-J2
REGION
(Mus
musculus) 		4 / 7 ASP L  82
SER L  18
SER L  74
ASN L  76
 None
 1.25A 1ig3A-2dqiL:
undetectable
1ig3B-2dqiL:
undetectable		 1ig3A-2dqiL:
15.59
1ig3B-2dqiL:
15.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ME7_A_MOAA600_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 2dqi LYSOZYME BINDING IG
KAPPA CHAIN V23-J2
REGION
(Mus
musculus) 		4 / 8 ASN L  32
ILE L  29
GLY L  68
GLY L  64
 None
 0.73A 1me7A-2dqiL:
undetectable		 1me7A-2dqiL:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SV9_A_DIFA701_1
(PHOSPHOLIPASE A2)		 2dqi LYSOZYME BINDING IG
KAPPA CHAIN V23-J2
REGION
(Mus
musculus) 		4 / 8 LEU L  33
ALA L  25
ILE L   2
GLY L  99
 None
 0.83A 1sv9A-2dqiL:
undetectable		 1sv9A-2dqiL:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCN_B_CHDB2_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2dqi LYSOZYME BINDING IG
KAPPA CHAIN V23-J2
REGION
(Mus
musculus) 		3 / 3 LEU L  21
LEU L  73
ARG L  61
 None
 0.74A 3hcnB-2dqiL:
undetectable		 3hcnB-2dqiL:
14.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F7L_B_ACTB503_0
(AMINE OXIDASE LKCE)		 2dqi LYSOZYME BINDING IG
KAPPA CHAIN V23-J2
REGION
(Mus
musculus) 		3 / 3 VAL L  78
GLU L  79
ILE L  75
 None
 0.65A 6f7lB-2dqiL:
undetectable		 6f7lB-2dqiL:
14.38