SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2dry'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_A_SPMA202_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 2dry 29-KDA
GALACTOSE-BINDING
LECTIN
(Lumbricus
terrestris) 		4 / 8 GLU A 196
GLU A 199
GLN A 197
ILE A 242
 None
 0.95A 4mj8A-2dryA:
undetectable		 4mj8A-2dryA:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_B_FK5B201_1
(FK506-BINDING
PROTEIN 1)		 2dry 29-KDA
GALACTOSE-BINDING
LECTIN
(Lumbricus
terrestris) 		5 / 11 PHE A 134
VAL A 214
ILE A 198
ILE A 158
ILE A 242
 None
 0.92A 5hw8B-2dryA:
undetectable		 5hw8B-2dryA:
25.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_G_FK5G201_2
(FK506-BINDING
PROTEIN 1)		 2dry 29-KDA
GALACTOSE-BINDING
LECTIN
(Lumbricus
terrestris) 		5 / 11 PHE A 134
VAL A 214
ILE A 219
ILE A 198
ILE A 242
 None
 1.26A 5hw8G-2dryA:
undetectable		 5hw8G-2dryA:
25.17