SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ds2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_A_VIBA501_1
(YKOF)		 2ds2 SWEET PROTEIN
MABINLIN-2 CHAIN B
(Capparis
masaikai) 		4 / 8 PHE B  49
LEU B  45
ILE B  38
ILE B  39
 None
 0.77A 1sbrA-2ds2B:
undetectable		 1sbrA-2ds2B:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_E_ASDE1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 2ds2 SWEET PROTEIN
MABINLIN-2 CHAIN A
SWEET PROTEIN
MABINLIN-2 CHAIN B
(Capparis
masaikai) 		5 / 9 LEU B   7
LEU B  14
ALA A  17
LEU A  15
ALA B  29
 None
 1.24A 2vcvE-2ds2B:
undetectable		 2vcvE-2ds2B:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_G_FK5G201_1
(FK506-BINDING
PROTEIN 1)		 2ds2 SWEET PROTEIN
MABINLIN-2 CHAIN B
(Capparis
masaikai) 		3 / 3 ILE B  61
PRO B  62
ILE B  64
 None
 0.28A 5hw8F-2ds2B:
undetectable		 5hw8F-2ds2B:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1N_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 2ds2 SWEET PROTEIN
MABINLIN-2 CHAIN B
(Capparis
masaikai) 		3 / 3 ALA B  51
ASN B  54
LEU B  55
 None
 0.23A 5i1nC-2ds2B:
undetectable		 5i1nC-2ds2B:
27.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1O_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 2ds2 SWEET PROTEIN
MABINLIN-2 CHAIN B
(Capparis
masaikai) 		3 / 3 ALA B  51
ASN B  54
LEU B  55
 None
 0.25A 5i1oC-2ds2B:
undetectable		 5i1oC-2ds2B:
27.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1P_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 2ds2 SWEET PROTEIN
MABINLIN-2 CHAIN B
(Capparis
masaikai) 		3 / 3 ALA B  51
ASN B  54
LEU B  55
 None
 0.26A 5i1pA-2ds2B:
undetectable		 5i1pA-2ds2B:
29.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1P_G_DVAG9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 2ds2 SWEET PROTEIN
MABINLIN-2 CHAIN B
(Capparis
masaikai) 		3 / 3 ALA B  51
ASN B  54
LEU B  55
 None
 0.32A 5i1pD-2ds2B:
undetectable		 5i1pD-2ds2B:
29.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_A_RITA602_2
(CYTOCHROME P450 3A5)		 2ds2 SWEET PROTEIN
MABINLIN-2 CHAIN A
SWEET PROTEIN
MABINLIN-2 CHAIN B
(Capparis
masaikai) 		3 / 3 ARG A  24
PHE B  49
LEU B  55
 None
 0.62A 5veuA-2ds2A:
undetectable		 5veuA-2ds2A:
5.47