SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2dt7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HXY_B_ACAB502_1
(PLM1)		 2dt7 SPLICING FACTOR 3
SUBUNIT 1
(Homo
sapiens) 		4 / 7 VAL B 166
SER B 160
GLN B 194
LEU B 204
 None
 1.24A 4hxyB-2dt7B:
undetectable		 4hxyB-2dt7B:
9.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UDC_A_DEXA1778_2
(GLUCOCORTICOID
RECEPTOR)		 2dt7 SPLICING FACTOR 3
SUBUNIT 1
(Homo
sapiens) 		3 / 3 MET B 186
GLN B 194
TYR B 193
 None
 0.81A 4udcA-2dt7B:
undetectable		 4udcA-2dt7B:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_C_P06C801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 2dt7 SPLICING FACTOR 3
SUBUNIT 1
(Homo
sapiens) 		4 / 7 ILE B 153
VAL B 166
ILE B 159
PHE B 162
 None
 0.96A 5hieC-2dt7B:
undetectable		 5hieC-2dt7B:
13.85