SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2dut'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_A_PFLA4002_1
(SERUM ALBUMIN)		 2dut HETEROCHROMATIN-ASSO
CIATED PROTEIN MENT
(Gallus
gallus) 		3 / 3 PHE A 149
LEU A 340
SER A 343
 None
 0.86A 1e7aA-2dutA:
undetectable		 1e7aA-2dutA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FXV_B_PNNB1001_0
(PENICILLIN ACYLASE)		 2dut HETEROCHROMATIN-ASSO
CIATED PROTEIN MENT
(Gallus
gallus) 		4 / 7 MET A  54
SER A   7
ALA A  40
PHE A  98
 None
 1.08A 1fxvA-2dutA:
undetectable
1fxvB-2dutA:
undetectable		 1fxvA-2dutA:
19.71
1fxvB-2dutA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_C_CCSC47_0
(GLUTATHIONE
S-TRANSFERASE)		 2dut HETEROCHROMATIN-ASSO
CIATED PROTEIN MENT
(Gallus
gallus) 		4 / 6 THR A  42
LEU A  44
GLY A 333
TYR A 132
 None
 1.21A 1gtiC-2dutA:
undetectable		 1gtiC-2dutA:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_F_CCSF47_0
(GLUTATHIONE
S-TRANSFERASE)		 2dut HETEROCHROMATIN-ASSO
CIATED PROTEIN MENT
(Gallus
gallus) 		4 / 5 THR A  42
LEU A  44
GLY A 333
TYR A 132
 None
 1.37A 1gtiF-2dutA:
undetectable		 1gtiF-2dutA:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_G_FUAG708_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2dut HETEROCHROMATIN-ASSO
CIATED PROTEIN MENT
(Gallus
gallus) 		5 / 11 PHE A 402
PHE A 203
LEU A 301
VAL A 383
PHE A 387
 None
 1.25A 1q23G-2dutA:
0.0		 1q23G-2dutA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUA_L_ACTL611_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 2dut HETEROCHROMATIN-ASSO
CIATED PROTEIN MENT
(Gallus
gallus) 		4 / 5 LEU A 114
TRP A  33
ASN A 106
LEU A 102
 None
 1.49A 1ruaH-2dutA:
0.0
1ruaL-2dutA:
0.0		 1ruaH-2dutA:
19.43
1ruaL-2dutA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUK_L_ACTL611_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 2dut HETEROCHROMATIN-ASSO
CIATED PROTEIN MENT
(Gallus
gallus) 		4 / 6 LEU A 114
TRP A  33
ASN A 106
LEU A 102
 None
 1.48A 1rukH-2dutA:
undetectable
1rukL-2dutA:
undetectable		 1rukH-2dutA:
19.43
1rukL-2dutA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUL_L_ACTL611_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 2dut HETEROCHROMATIN-ASSO
CIATED PROTEIN MENT
(Gallus
gallus) 		4 / 5 LEU A 114
TRP A  33
ASN A 106
LEU A 102
 None
 1.49A 1rulH-2dutA:
0.6
1rulL-2dutA:
0.0		 1rulH-2dutA:
19.43
1rulL-2dutA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_A_BEZA11_0
(CES1 PROTEIN)		 2dut HETEROCHROMATIN-ASSO
CIATED PROTEIN MENT
(Gallus
gallus) 		4 / 4 LEU A 312
SER A 349
LEU A  19
LEU A  15
 None
 1.15A 1yajA-2dutA:
undetectable		 1yajA-2dutA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BDM_A_TMIA501_1
(CYTOCHROME P450 2B4)		 2dut HETEROCHROMATIN-ASSO
CIATED PROTEIN MENT
(Gallus
gallus) 		4 / 7 MET A  54
LEU A  44
GLY A 333
THR A 335
 None
 1.11A 2bdmA-2dutA:
undetectable		 2bdmA-2dutA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BDM_A_TMIA501_1
(CYTOCHROME P450 2B4)		 2dut HETEROCHROMATIN-ASSO
CIATED PROTEIN MENT
(Gallus
gallus) 		4 / 7 SER A   7
LEU A  58
THR A 315
ILE A 310
 None
 1.01A 2bdmA-2dutA:
undetectable		 2bdmA-2dutA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OGY_B_C2FB4000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 2dut HETEROCHROMATIN-ASSO
CIATED PROTEIN MENT
(Gallus
gallus) 		5 / 12 PHE A 105
LEU A  15
GLY A   9
SER A   5
ILE A 399
 None
 1.14A 2ogyB-2dutA:
undetectable		 2ogyB-2dutA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BRF_A_SORA2_0
(LIN-12 AND GLP-1
PHENOTYPE PROTEIN 1,
ISOFORM A)		 2dut HETEROCHROMATIN-ASSO
CIATED PROTEIN MENT
(Gallus
gallus) 		3 / 3 LYS A   1
LYS A  94
VAL A   4
 None
 0.86A 3brfA-2dutA:
undetectable		 3brfA-2dutA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LB3_A_4CHA191_0
(DEHALOPEROXIDASE A)		 2dut HETEROCHROMATIN-ASSO
CIATED PROTEIN MENT
(Gallus
gallus) 		4 / 6 PHE A 195
TYR A 249
THR A 358
VAL A 351
 None
 1.30A 3lb3A-2dutA:
undetectable		 3lb3A-2dutA:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEL_B_QELB1_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
EPSILON-2)		 2dut HETEROCHROMATIN-ASSO
CIATED PROTEIN MENT
(Gallus
gallus) 		5 / 11 ILE A 391
PHE A 390
THR A 208
PRO A 302
GLU A 355
 None
 1.20A 3qelA-2dutA:
undetectable
3qelB-2dutA:
undetectable		 3qelA-2dutA:
21.67
3qelB-2dutA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEL_D_QELD2_2
(GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
EPSILON-2)		 2dut HETEROCHROMATIN-ASSO
CIATED PROTEIN MENT
(Gallus
gallus) 		5 / 9 ILE A 391
PHE A 390
THR A 208
PRO A 302
GLU A 355
 None
 1.20A 3qelD-2dutA:
undetectable		 3qelD-2dutA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AQL_A_TXCA1452_2
(GUANINE DEAMINASE)		 2dut HETEROCHROMATIN-ASSO
CIATED PROTEIN MENT
(Gallus
gallus) 		4 / 5 HIS A  59
LEU A 312
LEU A  19
ASP A 314
 None
 1.13A 4aqlA-2dutA:
undetectable		 4aqlA-2dutA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2X_A_TMQA202_2
(DIHYDROFOLATE
REDUCTASE)		 2dut HETEROCHROMATIN-ASSO
CIATED PROTEIN MENT
(Gallus
gallus) 		3 / 3 TRP A 163
GLN A 155
THR A 162
 None
 0.99A 4m2xA-2dutA:
undetectable		 4m2xA-2dutA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_C_29SC601_1
(ESTROGEN RECEPTOR)		 2dut HETEROCHROMATIN-ASSO
CIATED PROTEIN MENT
(Gallus
gallus) 		5 / 12 THR A  42
LEU A  44
ALA A  45
LEU A 133
LEU A 187
 None
 0.96A 4xi3C-2dutA:
undetectable		 4xi3C-2dutA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWJ_D_QELD503_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		 2dut HETEROCHROMATIN-ASSO
CIATED PROTEIN MENT
(Gallus
gallus) 		5 / 12 ILE A 391
PHE A 390
THR A 208
PRO A 302
GLU A 355
 None
 1.18A 5ewjC-2dutA:
undetectable
5ewjD-2dutA:
undetectable		 5ewjC-2dutA:
21.31
5ewjD-2dutA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEP_A_VDYA201_2
(CDL2.3B)		 2dut HETEROCHROMATIN-ASSO
CIATED PROTEIN MENT
(Gallus
gallus) 		5 / 9 ILE A  35
VAL A 164
LEU A 175
ILE A 172
LEU A 316
 None
 1.31A 5iepA-2dutA:
undetectable		 5iepA-2dutA:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA504_1
(CYTOCHROME P450 2C9)		 2dut HETEROCHROMATIN-ASSO
CIATED PROTEIN MENT
(Gallus
gallus) 		4 / 8 PHE A 195
ILE A 193
PHE A 401
PRO A  32
 None
 1.15A 5x23A-2dutA:
undetectable		 5x23A-2dutA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_D_CHDD401_0
(BILE SALT HYDROLASE)		 2dut HETEROCHROMATIN-ASSO
CIATED PROTEIN MENT
(Gallus
gallus) 		5 / 10 LEU A 102
ILE A 193
LEU A  39
ALA A  40
LEU A  41
 None
 1.18A 5y7pD-2dutA:
undetectable		 5y7pD-2dutA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_G_CHDG401_0
(BILE SALT HYDROLASE)		 2dut HETEROCHROMATIN-ASSO
CIATED PROTEIN MENT
(Gallus
gallus) 		5 / 10 LEU A 102
ILE A 193
LEU A  39
ALA A  40
LEU A  41
 None
 1.14A 5y7pG-2dutA:
undetectable		 5y7pG-2dutA:
20.37