SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2duy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_B_CHDB2503_0
(FERROCHELATASE)		 2duy COMPETENCE PROTEIN
COMEA-RELATED
PROTEIN
(Thermus
thermophilus) 		4 / 4 LEU A  66
PRO A  63
LEU A  56
ARG A  51
 None
 1.01A 1hrkB-2duyA:
undetectable		 1hrkB-2duyA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_C_115C4_1
(HMG-COA REDUCTASE)		 2duy COMPETENCE PROTEIN
COMEA-RELATED
PROTEIN
(Thermus
thermophilus) 		4 / 7 ARG A  74
VAL A  19
SER A  20
ASN A  22
 None
 1.37A 1hwiC-2duyA:
undetectable		 1hwiC-2duyA:
11.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_D_115D3_2
(HMG-COA REDUCTASE)		 2duy COMPETENCE PROTEIN
COMEA-RELATED
PROTEIN
(Thermus
thermophilus) 		4 / 7 ARG A  74
VAL A  19
SER A  20
ASN A  22
 None
 1.37A 1hwiD-2duyA:
undetectable		 1hwiD-2duyA:
11.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_B_CHDB1604_0
(FERROCHELATASE)		 2duy COMPETENCE PROTEIN
COMEA-RELATED
PROTEIN
(Thermus
thermophilus) 		4 / 4 LEU A  66
PRO A  63
LEU A  56
ARG A  51
 None
 0.99A 2hrcB-2duyA:
undetectable		 2hrcB-2duyA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2duy COMPETENCE PROTEIN
COMEA-RELATED
PROTEIN
(Thermus
thermophilus) 		4 / 4 LEU A  66
PRO A  63
LEU A  56
ARG A  51
 None
 1.07A 2pnjB-2duyA:
undetectable		 2pnjB-2duyA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD2_A_CHDA426_0
(FERROCHELATASE)		 2duy COMPETENCE PROTEIN
COMEA-RELATED
PROTEIN
(Thermus
thermophilus) 		4 / 4 LEU A  66
PRO A  63
LEU A  56
ARG A  51
 None
 1.11A 2qd2A-2duyA:
undetectable		 2qd2A-2duyA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AI9_X_SAMX501_0
(UPF0217 PROTEIN
MJ1640)		 2duy COMPETENCE PROTEIN
COMEA-RELATED
PROTEIN
(Thermus
thermophilus) 		5 / 9 LEU A  32
ILE A  35
GLY A  34
LEU A  73
LEU A  66
 None
 0.99A 3ai9X-2duyA:
undetectable		 3ai9X-2duyA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCO_A_CHDA3_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2duy COMPETENCE PROTEIN
COMEA-RELATED
PROTEIN
(Thermus
thermophilus) 		4 / 4 LEU A  66
PRO A  63
LEU A  56
ARG A  51
 None
 1.22A 3hcoA-2duyA:
undetectable		 3hcoA-2duyA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCO_B_CHDB1_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2duy COMPETENCE PROTEIN
COMEA-RELATED
PROTEIN
(Thermus
thermophilus) 		4 / 4 LEU A  66
PRO A  63
LEU A  56
ARG A  51
 None
 1.17A 3hcoB-2duyA:
undetectable		 3hcoB-2duyA:
16.79